Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thin ventricular wall 1 | 24

Disease

Cancer 4 | 2,499
Carcinoma 4 | 11,493
Multiple myeloma 3 | 1,332
Neurodegenerative disease 3 | 414
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Big calvaria 2 | 147
Dementia 2 | 175
Depressive disorder 2 | 409
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Fetal Growth Retardation 2 | 189
Frontal bossing 2 | 157
Gait abnormality 2 | 135
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Nerve Degeneration 2 | 121
Ovarian Neoplasms 2 | 102
Pick disease 2 | 1,894
Short stature 2 | 531
astrocytoma 2 | 1,146
glioblastoma 2 | 5,792
progressive supranuclear palsy 2 | 676
Abnormal brain FDG positron emission tomography 1 | 9
Abnormality of the calcaneus 1 | 2
Absent frontal sinuses 1 | 8
Alexia 1 | 6
Aplasia of frontal sinus 1 | 8
Apraxias 1 | 27
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 13
Back Pain 1 | 7
Behavioral variant of frontotemporal dementia 1 | 8
Biliary cirrhosis 1 | 45
Bronchioloalveolar Adenocarcinoma 1 | 14
Compulsive hoarding 1 | 7
Decreased calcification of skull 1 | 10
Decreased pneumatization of frontal sinus 1 | 6
Defect of skull ossification 1 | 10
Developmental arithmetic disorder 1 | 8
Difficulty making arithmetical calculations 1 | 8
Dysphasia 1 | 23
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Fasciculation, Tongue 1 | 8
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Fibrous Dysplasia of Bone 1 | 2
Frontotemporal cerebral atrophy 1 | 8
Grammar-specific speech disorder 1 | 6
Hammer Toe 1 | 23
High pitched voice 1 | 23
Hyperorality 1 | 7
Hypoplastic frontal sinuses 1 | 6
Hypoplastic iliac wing 1 | 19
Hypotrophic frontal sinus 1 | 6
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Irritation - emotion 1 | 68
Learning Disorders 1 | 29
Leprosy 1 | 73
Liver Cirrhosis, Biliary 1 | 33
Lower limb hyperreflexia 1 | 10
Memory Disorders 1 | 40
Metaphyseal chondrodysplasia 1 | 7
Mild Mental Retardation 1 | 70
Mulibrey nanism 1 | 13
Muscle Cramp 1 | 55
Osteitis Fibrosa Disseminata 1 | 2
Ovarian Cysts 1 | 41
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
Platyspondyly 1 | 56
Primary Progressive Nonfluent Aphasia 1 | 7
Problems speaking 1 | 37
Progressive non-fluent aphasia 1 | 7
Reflex, Ankle, Absent 1 | 8
Repeated speech 1 | 9
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Retinitis pigmentosa 18 1 | 16
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Secondary Parkinson Disease 1 | 10
Semantic Dementia 1 | 7
Short hands 1 | 50
Shoulder girdle muscle atrophy 1 | 6
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Spoken Word Recognition Deficit 1 | 6
Temporal cortical atrophy 1 | 6
Winged scapula 1 | 23
Xerostomia 1 | 42
Young onset Parkinson disease 1 | 10

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 3 | 4,145
Epigenetic 1 | 242
Non-IDG 1 | 12,091

GO Process

aggresome assembly 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25892 1754.8 177
Ubiquitin D UBD Tbio Non-IDG -2.35231 223.1 210
E3 ubiquitin-protein ligase parkin PRKN Tbio Enzyme -2.99618 1004.1 533
Histone deacetylase 6 HDAC6 Tclin Epigenetic -2.72354 545.3 725
Transitional endoplasmic reticulum ATPase VCP Tchem Enzyme -2.84978 736.4 416