Development Level

Tbio 24 | 11,651
Tdark 4 | 6,593
Tchem 3 | 1,388

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal stomach morphology 1 | 10
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
glioblastoma 12 | 5,792
medulloblastoma, large-cell 11 | 6,241
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 9 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
psoriasis 9 | 6,694
Autosomal recessive predisposition 8 | 1,442
lung cancer 8 | 4,740
Cerebellar Ataxia 6 | 304
breast carcinoma 6 | 1,638
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Optic Atrophy 5 | 242
Poor school performance 5 | 645
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
Breast cancer 4 | 3,578
Epilepsy 4 | 792
Heart failure 4 | 162
Increased serum lactate 4 | 60
Nystagmus 4 | 317
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
adult high grade glioma 4 | 3,801
cytochrome-c oxidase deficiency disease 4 | 19
diabetes mellitus 4 | 1,728
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
Abdominal Pain 3 | 98
Acidosis, Lactic 3 | 97
Atopic dermatitis 3 | 952
Blepharoptosis 3 | 231
Cancer 3 | 2,499
Cardiomyopathies 3 | 110
Congestive heart failure 3 | 113
Cytochrome-c Oxidase Deficiency 3 | 17
Dysarthria 3 | 192
Dystonia 3 | 164
Fatigue 3 | 182
Hypertensive disease 3 | 292
Infantile onset 3 | 238
Lactic acidemia 3 | 95
Muscle hypotonia 3 | 571
Nausea and vomiting 3 | 97
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Obesity 3 | 678
Ophthalmoplegia 3 | 106
Paraganglioma 3 | 15
Persistent generalized lymphadenopathy 3 | 15
Pick disease 3 | 1,894
Retinitis Pigmentosa 3 | 226
Sensorineural Hearing Loss (disorder) 3 | 284
Strabismus 3 | 270
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
Animal Mammary Neoplasms 2 | 136
Big calvaria 2 | 147
CSF lactate increased 2 | 33
Chondroma 2 | 15
Congenital deafness 2 | 185
Deafness 2 | 198
Hearing Loss, Partial 2 | 185
Hyperhidrosis disorder 2 | 81
Hypertrophic Cardiomyopathy 2 | 117
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased sweating 2 | 81
Intestinal Obstruction 2 | 31
Lipoma 2 | 32
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Melanocytic nevus 2 | 43
Mood swings 2 | 77
Muscle Weakness 2 | 170
Noncancerous mole 2 | 28
Nonsyndromic deafness 2 | 142
Respiratory Failure 2 | 104
Sweating 2 | 81
Tinnitus 2 | 19
Weight decreased 2 | 103
hearing impairment 2 | 199
inflammatory breast cancer 2 | 286

Tissue

Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Respiratory system 30 | 16,393

Target Family

Enzyme 14 | 4,145
Non-IDG 14 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

GO Process

aerobic respiration 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-c1 complex subunit 6-like, mitochondrial UQCRHL Tdark Non-IDG -0.84371 11.5 0
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 CHCHD5 Tbio Non-IDG -1.04467 11.6 88
Pantothenate kinase 2, mitochondrial PANK2 Tbio Kinase -2.24581 177.7 253
Mitochondrial fission regulator 2 MTFR2 Tdark Non-IDG 0.02 1.03 46
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.06552 12.3 194
Cytochrome b-c1 complex subunit 7 UQCRB Tbio Non-IDG -1.29421 22.8 112
Mitochondrial-processing peptidase subunit beta PMPCB Tbio Enzyme -1.79941 62.1 118
Cytochrome c oxidase protein 20 homolog COX20 Tbio Enzyme -0.89632 8.42 52
Surfeit locus protein 1 SURF1 Tbio Non-IDG -2.05564 112.5 104
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial SDHB Tbio Enzyme -2.68774 460.2 321