Development Level

Tbio 17 | 10,625
Tchem 7 | 1,890
Tclin 5 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

abnormal behavior 4 | 226
hyperactivity 2 | 108
hypoactivity 2 | 89
increased circulating alkaline... 2 | 119
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal snout morphology 1 | 18
abnormal spine curvature 1 | 7
abnormal tooth morphology 1 | 24
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased respiratory quotient 1 | 12
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
increased circulating HDL chol... 1 | 63
increased circulating glucose ... 1 | 16
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased kidney weight 1 | 4
increased lean body mass 1 | 107
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
rib fusion 1 | 2
syndactyly 1 | 4
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

glioblastoma 16 | 5,572
osteosarcoma 16 | 7,933
medulloblastoma, large-cell 15 | 6,234
atypical teratoid / rhabdoid tumor 14 | 4,369
oligodendroglioma 14 | 2,849
lung carcinoma 11 | 2,844
pilocytic astrocytoma 11 | 3,086
lung cancer 10 | 4,466
ovarian cancer 10 | 8,484
psoriasis 10 | 6,685
subependymal giant cell astrocytoma 10 | 2,287
astrocytic glioma 9 | 2,241
pediatric high grade glioma 9 | 2,712
Parkinson's disease 8 | 364
adult high grade glioma 8 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
posterior fossa group A ependymoma 7 | 1,511
primitive neuroectodermal tumor 7 | 3,031
Pick disease 6 | 1,893
ependymoma 6 | 2,514
medulloblastoma 6 | 1,524
Breast cancer 5 | 3,094
Cancer 5 | 2,346
Carcinoma 5 | 2,147
Epilepsy 5 | 346
Neurodegenerative disease 5 | 383
group 3 medulloblastoma 5 | 2,254
invasive ductal carcinoma 5 | 2,950
malignant mesothelioma 5 | 3,162
pituitary cancer 5 | 1,972
Intellectual disability 4 | 573
Obesity 4 | 616
atypical teratoid/rhabdoid tumor 4 | 1,095
cutaneous lupus erythematosus 4 | 1,056
group 4 medulloblastoma 4 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
posterior fossa group B ependymoma 4 | 1,530
Amphetamine-Related Disorders 3 | 74
Atopic dermatitis 3 | 944
Autistic Disorder 3 | 320
Catalepsy 3 | 15
Cerebellar Ataxia 3 | 72
Down syndrome 3 | 548
General anesthesia 3 | 53
Movement Disorders 3 | 21
Neuropathy 3 | 210
Parkinson Disease 3 | 102
Parkinsonism 3 | 19
Schizophrenia 3 | 501
Seizures 3 | 95
astrocytoma 3 | 1,493
glioblastoma multiforme 3 | 347
interstitial cystitis 3 | 2,299
lung adenocarcinoma 3 | 2,713
non-small cell lung cancer 3 | 2,798
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis 3 | 1,557
Acromegaly 2 | 40
Adenoma 2 | 165
Alcohol dependence 2 | 107
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 431
Anorexia nervosa 2 | 59
Ataxia 2 | 15
Attention deficit hyperactivity disorder 2 | 156
Bipolar Disorder 2 | 266
Bipolar disorder in remission 2 | 19
Bradycardia 2 | 24
Brain disease 2 | 83
Cocaine-Related Disorders 2 | 88
Dementia 2 | 129
Dyskinesia, Drug-Induced 2 | 15
Dystonia 2 | 77
Endometriosis 2 | 535
Gastroesophageal reflux disease 2 | 37
Heroin dependence 2 | 30
Huntington's disease 2 | 72
Hyperactive behavior 2 | 31
Hypertensive disease 2 | 193
Hypogonadism 2 | 70
Hypotension 2 | 53
Itching of skin 2 | 19
Migraine 2 | 79
Narcolepsy 2 | 58
Nicotine dependence 2 | 53
PARKINSON DISEASE, LATE-ONSET 2 | 18
Pain 2 | 70
Pathological gambling 2 | 16
Pituitary adenoma 2 | 35
Postencephalitic parkinsonism 2 | 12
Renal Cell Carcinoma 2 | 199
Tachycardia 2 | 17
aldosterone-producing adenoma 2 | 664
cystic fibrosis 2 | 1,665
ductal carcinoma in situ 2 | 1,745
head and neck cancer 2 | 270
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795

Tissue

Cardiovascular System 29 | 17,958
Digestive Tract 29 | 18,473
Endocrine System 29 | 18,512
Female tissues 29 | 18,647
Liver and Pancreas 29 | 18,136
Male tissues 29 | 17,969
Nervous System 29 | 18,561
Skin and soft tissues 29 | 18,115
Urinary Tract 29 | 18,444
Blood and immune system 28 | 17,995
Respiratory system 28 | 17,484

Target Family

Non-IDG 13 | 11,971
Ion Channel 5 | 341
Enzyme 3 | 4,146
Transcription Factor 3 | 1,400
GPCR 2 | 406
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

adult walking behavior 29 | 29
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.15613 15.9 85
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.66342 512.8 226
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.55598 368.4 441
ATP-sensitive inward rectifier potassium channel 10 KCNJ10 Tchem Ion Channel -2.36059 245.7 127
Ephrin type-A receptor 4 EPHA4 Tchem Kinase -2.31936 234.5 411
Disabled homolog 1 DAB1 Tbio Non-IDG -0.36015 3.38 368
Spectrin beta chain, non-erythrocytic 4 SPTBN4 Tbio Non-IDG -1.18108 16.6 22
Ubiquitin carboxyl-terminal hydrolase isozyme L1 UCHL1 Tchem Enzyme -3.12706 1364.7 1241
Beta-arrestin-2 ARRB2 Tbio Non-IDG -2.64309 434.6 229