Development Level

Tbio 10 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 7 | 11,493
Congenital heart disease 5 | 93
psoriasis 5 | 6,694
Cardiomyopathy 4 | 116
Cardiomyopathy, Dilated 4 | 83
Myocardial Infarction 4 | 151
Abnormality of metabolism/homeostasis 3 | 134
Atrial Fibrillation 3 | 124
Atrial Septal Defects 3 | 85
Autosomal recessive predisposition 3 | 1,442
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Conduction disorder of the heart 3 | 79
Dilated cardiomyopathy 3 | 56
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Familial isolated dilated cardiomyopathy 3 | 41
Feeding difficulties 3 | 127
Hypertrophic Cardiomyopathy 3 | 117
Hypothyroidism 3 | 122
Kidney cancer 3 | 2,613
LEFT VENTRICULAR NONCOMPACTION 10 3 | 40
LEFT VENTRICULAR NONCOMPACTION 8 3 | 40
Myopathy 3 | 185
Tetralogy of Fallot 3 | 63
acute quadriplegic myopathy 3 | 1,158
Asymmetric Septal Hypertrophy 2 | 7
Atrial heart septal defect 2 | 18
Attention deficit hyperactivity disorder 2 | 278
Bell Palsy 2 | 58
Blepharoptosis 2 | 231
Cardiomyopathy, Familial Hypertrophic, 1 2 | 6
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 2 | 7
Cardiomyopathy, Hypertrophic, Familial 2 | 9
Cerebrovascular disease 2 | 238
Cleft Palate 2 | 271
Congestive heart failure 2 | 113
Creatine phosphokinase serum increased 2 | 110
Cryptorchidism 2 | 296
Deglutition Disorders 2 | 132
Distal arthrogryposis 2 | 42
Double Outlet Right Ventricle 2 | 11
Ebstein anomaly 2 | 16
Elevated creatine kinase 2 | 110
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Failure to gain weight 2 | 365
Fatigue 2 | 182
Fever 2 | 138
Heart Defects, Congenital 2 | 37
Heart disease 2 | 306
Heart failure 2 | 162
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Liver cancer 2 | 604
Melanoma 2 | 711
Muscle hypotonia 2 | 571
Narrow face 2 | 54
Ostium secundum atrial septal defect 2 | 9
Parkinson's disease 2 | 392
Patent ductus arteriosus 2 | 90
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Right atrial isomerism 2 | 29
Skin cancer 2 | 469
Subaortic stenosis 2 | 9
Sudden death 2 | 16
Thin face 2 | 54
Umbilical hernia 2 | 93
Ventricular Septal Defects 2 | 119
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
CLEFT CHIN 1 | 9
Dermal Necrosis 1 | 6
Diagnostic Test for Pheochromocytoma 1 | 6
Erectile abnormalities 1 | 16
Headache disorder 1 | 19
Hypertension Secondary to Pheochromocytoma 1 | 6
Hypertensive emergency 1 | 3
Influenza-like symptoms 1 | 16
Myotonic Dystrophy 1 | 3
Paroxysmal hypertension 1 | 6
Prevention of Hypertension in Pheochromocytoma 1 | 6
Prevention of Posterior Synechiae 1 | 4
Rectal pain 1 | 3
Reverse Mydriasis from Ophthalmic Adrenergic or Anticholinergic Agent 1 | 2
Seasonal allergic rhinitis 1 | 9
Sense of smell impaired 1 | 21
Sinus headache 1 | 16
Ventricular Remodeling 1 | 5
Wheezing 1 | 7

Tissue

Cardiovascular System 11 | 15,192
Female tissues 11 | 17,400
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Liver and Pancreas 10 | 16,750
Blood and immune system 9 | 16,909
Male tissues 9 | 17,142
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Nervous System 8 | 16,725
Respiratory system 7 | 16,393

Target Family

Non-IDG 5 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

adult heart development 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.36066 28.2 70
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
Myosin-7 MYH7 Tbio Non-IDG -2.64013 417.6 176
Bone morphogenetic protein 10 BMP10 Tbio Non-IDG -1.43436 26.2 268
Heart- and neural crest derivatives-expressed protein 2 HAND2 Tbio Transcription Factor -2.99854 926.7 220
CDK-activating kinase assembly factor MAT1 MNAT1 Tbio Enzyme -2.13005 133.6 161
Telethonin TCAP Tbio Non-IDG -3.33021 2076.3 97
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385