Development Level

Tbio 17 | 11,445
Tclin 13 | 613
Tchem 12 | 1,598
Tdark 1 | 6,588

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 4 | 298
preweaning lethality, complete... 4 | 979
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased vertical activity 2 | 208
hyperactivity 2 | 148
increased circulating calcium ... 2 | 34
increased fasted circulating g... 2 | 76
abnormal coat-hair pigmentatio... 1 | 64
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
decreased IgE level 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
edema 1 | 59
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating lipase l... 1 | 3
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small testis 1 | 58
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 33 | 11,493
medulloblastoma, large-cell 19 | 6,241
psoriasis 16 | 6,694
osteosarcoma 15 | 7,950
glioblastoma 14 | 5,792
atypical teratoid / rhabdoid tumor 13 | 5,112
adult high grade glioma 12 | 3,801
group 3 medulloblastoma 12 | 4,104
lung carcinoma 12 | 2,843
colon cancer 11 | 1,478
ovarian cancer 11 | 8,520
ependymoma 10 | 4,679
invasive ductal carcinoma 10 | 2,951
lung adenocarcinoma 10 | 2,716
lung cancer 10 | 4,740
non-small cell lung cancer 10 | 2,890
astrocytic glioma 9 | 2,597
primitive neuroectodermal tumor 9 | 3,035
Bipolar Disorder 8 | 666
Obesity 8 | 678
Parkinson's disease 8 | 392
oligodendroglioma 8 | 2,850
ulcerative colitis 8 | 1,819
Cancer 7 | 2,499
Depressive disorder 7 | 409
breast carcinoma 7 | 1,638
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Allergic rhinitis 6 | 94
Asthma 6 | 385
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
Epilepsy 6 | 792
Kidney cancer 6 | 2,613
Major Depressive Disorder 6 | 301
Mood Disorders 6 | 184
Schizophrenia 6 | 1,160
Autosomal recessive predisposition 5 | 1,442
Common cold 5 | 67
Headache disorder 5 | 19
Hypertension 5 | 396
Hypotension 5 | 82
Influenza-like symptoms 5 | 16
Sinus headache 5 | 16
adrenocortical carcinoma 5 | 1,428
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
Acute exacerbation of asthma 4 | 14
Alcoholic Intoxication, Chronic 4 | 289
Asthma management 4 | 19
Bronchitis 4 | 43
Crohn's disease 4 | 321
Fever 4 | 138
Hypertensive disorder 4 | 56
Liver Cirrhosis, Experimental 4 | 769
Mental Depression 4 | 333
Multiple Sclerosis 4 | 540
Nasal congestion 4 | 21
Nasal discharge 4 | 24
Orthostatic hypotension 4 | 9
Pick disease 4 | 1,894
Pulmonary emphysema 4 | 48
Seizures 4 | 596
Substance Withdrawal Syndrome 4 | 55
Unipolar Depression 4 | 250
adrenocortical adenoma 4 | 131
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Administration of Local Anesthetic Nerve Block 3 | 14
Alcohol dependence 3 | 107
Anorexia 3 | 43
Anxiety Disorders 3 | 38
Cardiomyopathies 3 | 110
Dyspnea 3 | 76
Endometriosis 3 | 540
Heart disease 3 | 306
Heart failure 3 | 162
Hyperlipidemia 3 | 43
Local anesthesia, by infiltration 3 | 14
Lung diseases 3 | 50
Open-angle glaucoma 3 | 27
Panic disorder 3 | 61
Rhinitis 3 | 54
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
medulloblastoma 3 | 720
post-traumatic stress disorder 3 | 40
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 42 | 18,159
Digestive Tract 39 | 17,369
Skin and soft tissues 38 | 17,230
Blood and immune system 37 | 16,909
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 35 | 16,393
Urinary Tract 35 | 16,678
Cardiovascular System 29 | 15,192

Target Family

GPCR 24 | 408
Non-IDG 13 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344

GO Process

adenylate cyclase-modulating G... 43 | 43
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Tsukushin TSKU Tdark Non-IDG -2.65097 441.7 48
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.90666 762.6 254
Alpha-1B adrenergic receptor ADRA1B Tclin GPCR -2.30594 201.5 364
Beta-3 adrenergic receptor ADRB3 Tclin GPCR -2.73090 568.4 254