Development Level

Tbio 22 | 11,445
Tclin 13 | 613
Tchem 8 | 1,598

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal bone structure 5 | 187
decreased bone mineral content 4 | 151
decreased vertical activity 4 | 208
decreased lean body mass 3 | 135
increased heart weight 3 | 62
increased startle reflex 3 | 112
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased body length 2 | 101
decreased bone mineral density 2 | 126
improved glucose tolerance 2 | 79
increased circulating calcium ... 2 | 34
increased total body fat amoun... 2 | 134
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal male genitalia morpho... 1 | 3
abnormal ovary morphology 1 | 7
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased IgE level 1 | 6
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
enlarged heart atrium 1 | 4
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating lipase l... 1 | 3
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
polysyndactyly 1 | 2
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 32 | 11,493
psoriasis 18 | 6,694
ovarian cancer 17 | 8,520
Kidney cancer 14 | 2,613
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
adult high grade glioma 12 | 3,801
astrocytic glioma 12 | 2,597
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 11 | 4,679
lung cancer 11 | 4,740
Astrocytoma, Pilocytic 10 | 3,081
Cancer 10 | 2,499
Bipolar Disorder 9 | 666
oligodendroglioma 9 | 2,850
Obesity 8 | 678
Osteoporosis 8 | 363
diabetes mellitus 8 | 1,728
group 3 medulloblastoma 8 | 4,104
lung carcinoma 8 | 2,843
pancreatic cancer 8 | 2,398
Adenoma 7 | 167
Autosomal recessive predisposition 7 | 1,442
Breast cancer 7 | 3,578
Depressive disorder 7 | 409
Hypertension 7 | 396
Hypoparathyroidism 7 | 41
Hypothyroidism 7 | 122
Pseudohypoparathyroidism 7 | 18
group 4 medulloblastoma 7 | 1,855
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
Alcoholic Intoxication, Chronic 6 | 289
Epilepsy 6 | 792
Hyperthyroidism 6 | 53
Schizophrenia 6 | 1,160
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
Acquired metabolic disease 5 | 336
Acromegaly 5 | 51
Brachydactyly 5 | 156
Cushing's syndrome 5 | 48
Hyperactive behavior 5 | 91
Hypercalcemia 5 | 59
Hyperparathyroidism 5 | 48
Hypertensive disease 5 | 292
Hypogonadism 5 | 173
Hypophosphatemia 5 | 40
Kidney disease 5 | 430
Liver cancer 5 | 604
Polycystic ovary syndrome 5 | 360
Short stature 5 | 531
Substance Withdrawal Syndrome 5 | 55
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
ulcerative colitis 5 | 1,819
Acrodysostosis 4 | 12
Adrenal gland cancer 4 | 12
Alzheimer's disease 4 | 658
Attention deficit hyperactivity disorder 4 | 278
Fibrous dysplasia 4 | 15
Hyperkinesis 4 | 32
Hyperphosphatemia 4 | 32
Infertility 4 | 188
Intellectual disability 4 | 1,016
Major Depressive Disorder 4 | 301
McCune Albright syndrome 4 | 19
Melanoma 4 | 711
Mental Depression 4 | 333
Migraine 4 | 83
Multiple Endocrine Neoplasia Type 1 4 | 29
Osteosclerosis 4 | 31
Pick disease 4 | 1,894
Pituitary adenoma 4 | 38
Plummer's disease 4 | 11
Seizures 4 | 596
Skin cancer 4 | 469
Thyroid cancer 4 | 36
Unipolar Depression 4 | 250
Dystonia 3 | 164
Hypoglycemia 3 | 152
Isolated cases 3 | 72
Mood Disorders 3 | 184
Rickets 3 | 49
Short metacarpal 3 | 43
Thyrotoxicosis 3 | 38
head and neck cancer 3 | 271
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
substance-related disorder 3 | 162
tuberculosis 3 | 2,010

Tissue

Endocrine System 39 | 18,159
Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Nervous System 33 | 16,725
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Male tissues 31 | 17,142
Respiratory system 31 | 16,393
Blood and immune system 30 | 16,909
Cardiovascular System 28 | 15,192

Target Family

GPCR 21 | 408
Non-IDG 13 | 12,091
Enzyme 9 | 4,145

GO Process

adenylate cyclase-activating G... 43 | 43
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Urocortin-2 UCN2 Tbio Non-IDG -2.05990 129.7 107
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.61657 45.3 134
Adenylate cyclase type 4 ADCY4 Tbio Enzyme -2.04603 107.6 156
ADM2 ADM2 Tbio Non-IDG -2.49800 325.5 139