Development Level

Tbio 92 | 10,625
Tchem 26 | 1,890
Tdark 11 | 7,003
Tclin 10 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 26
GPCR: IDG Consortium (Targets) 1 | 127

IMPC Phenotype

decreased lean body mass 4 | 195
preweaning lethality, complete... 4 | 633
embryonic lethality prior to t... 3 | 187
decreased bone mineral content 2 | 157
decreased circulating alanine ... 2 | 53
decreased total body fat amoun... 2 | 186
abnormal eye posterior chamber... 1 | 3
abnormal heart position or ori... 1 | 1
abnormal seminal vesicle morph... 1 | 47
decreased body weight 1 | 174
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased heart rate 1 | 10
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
female infertility 1 | 34
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD8 alpha bet... 1 | 2
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260
prolonged RR interval 1 | 2

Disease

osteosarcoma 74 | 7,933
ovarian cancer 58 | 8,491
lung cancer 50 | 4,473
psoriasis 49 | 6,685
interstitial cystitis 48 | 2,299
lung carcinoma 47 | 2,844
Cancer 44 | 2,346
glioblastoma 43 | 5,572
cutaneous lupus erythematosus 41 | 1,056
ulcerative colitis 39 | 2,087
medulloblastoma, large-cell 37 | 6,234
primary Sjogren syndrome 37 | 788
tuberculosis 34 | 1,563
invasive ductal carcinoma 32 | 2,950
pilocytic astrocytoma 30 | 3,086
subependymal giant cell astrocytoma 28 | 2,287
non-small cell lung cancer 24 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
lung adenocarcinoma 21 | 2,714
malignant mesothelioma 21 | 3,163
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
pancreatic cancer 20 | 2,300
Rheumatoid Arthritis 19 | 1,170
atypical teratoid / rhabdoid tumor 18 | 4,369
pediatric high grade glioma 18 | 2,712
Breast cancer 17 | 3,098
oligodendroglioma 17 | 2,849
cystic fibrosis 16 | 1,670
diabetes mellitus 16 | 1,663
Multiple Sclerosis 15 | 498
Carcinoma 14 | 2,147
adult high grade glioma 14 | 2,148
colon cancer 14 | 1,475
head and neck cancer and chronic obstructive pulmonary disease 14 | 237
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
mucosa-associated lymphoid tissue lymphoma 14 | 480
astrocytoma 13 | 1,493
ductal carcinoma in situ 13 | 1,745
Crohn's disease 12 | 304
Multiple myeloma 12 | 1,327
active Crohn's disease 12 | 918
ependymoma 12 | 2,514
juvenile dermatomyositis 12 | 1,189
periodontitis 12 | 269
primitive neuroectodermal tumor 12 | 3,031
sarcoidosis 12 | 368
IGA Glomerulonephritis 11 | 454
acute myeloid leukemia 11 | 785
dermatomyositis 11 | 966
group 4 medulloblastoma 11 | 1,875
Hypersensitivity reaction type II disease 10 | 235
Waldenstrons macroglobulinemia 10 | 764
chronic lymphocytic leukemia 10 | 244
esophageal adenocarcinoma 10 | 737
gastric cancer 10 | 436
primary pancreatic ductal adenocarcinoma 10 | 1,271
Asthma 9 | 349
Hepatitis B 9 | 103
astrocytic glioma 9 | 2,241
breast carcinoma 9 | 1,614
chronic lymphosyte leukemia 9 | 232
group 3 medulloblastoma 9 | 2,254
nasopharyngeal carcinoma 9 | 1,056
posterior fossa group A ependymoma 9 | 1,511
Anemia 8 | 252
Arthritis 8 | 248
Common variable immunodeficiency 8 | 98
Hepatitis C 8 | 90
Human immunodeficiency virus infectious disease 8 | 129
Influenza 8 | 142
Lupus erythematosus 8 | 80
Melanoma 8 | 261
Pick disease 8 | 1,893
medulloblastoma 8 | 1,524
pancreatic carcinoma 8 | 567
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
pituitary cancer 8 | 1,972
Allergic hypersensitivity disease 7 | 123
Kidney disease 7 | 397
Leprosy 7 | 77
Severe Combined Immunodeficiency 7 | 46
tuberculosis and treatment for 3 months 7 | 327
Adult T-Cell Lymphoma/Leukemia 6 | 30
Agammaglobulinemia 6 | 24
Atopic dermatitis 6 | 944
Autistic Disorder 6 | 320
Blastic phase chronic myeloid leukemia 6 | 58
Celiac disease 6 | 112
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
Liver disease 6 | 219
Peripheral Neuropathy 6 | 303
gastric carcinoma 6 | 832
inflammatory breast cancer 6 | 404
progressive supranuclear palsy 6 | 674
sonic hedgehog group medulloblastoma 6 | 1,482
tuberculosis and treatment for 6 months 6 | 686
Duchenne muscular dystrophy 5 | 602
Prostatic Neoplasms 5 | 471
Schizophrenia 5 | 503
adrenocortical carcinoma 5 | 1,427

Tissue

Nervous System 136 | 18,560
Digestive Tract 135 | 18,472
Female tissues 134 | 18,646
Urinary Tract 133 | 18,443
Skin and soft tissues 131 | 18,114
Blood and immune system 130 | 17,994
Endocrine System 129 | 18,511
Liver and Pancreas 126 | 18,135
Cardiovascular System 125 | 17,957
Respiratory system 124 | 17,483
Male tissues 120 | 17,968

Target Family

Non-IDG 100 | 11,969
Kinase 19 | 634
Enzyme 11 | 4,146
Transcription Factor 4 | 1,400
GPCR 2 | 408
Ion Channel 2 | 341
TF/Epigenetic 1 | 38

GO Process

adaptive immune response 139 | 139
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoplasmic reticulum aminopeptidase 2 ERAP2 Tchem Enzyme -1.68056 46.0 70
E3 ubiquitin-protein ligase RNF19B RNF19B Tbio Enzyme -0.75299 6.71 85
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.28015 198.7 195
Protein artemis DCLRE1C Tbio Non-IDG -2.25361 45.4 225
Membrane cofactor protein CD46 Tbio Non-IDG -2.92514 849.0 564
Junctional adhesion molecule C JAM3 Tbio Non-IDG -1.89346 55.4 183
Tumor necrosis factor ligand superfamily member 18 TNFSF18 Tbio Non-IDG -1.73179 58.4 291
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.00230 103.9 435
C-type lectin domain family 4 member A CLEC4A Tbio Non-IDG -1.61906 47.0 180
SLAM family member 7 SLAMF7 Tclin Non-IDG -1.63615 47.5 269