Development Level

Tbio 103 | 11,445
Tdark 65 | 6,588
Tchem 27 | 1,598
Tclin 14 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal seminal vesicle morph... 4 | 114
decreased lean body mass 4 | 135
embryonic lethality prior to t... 4 | 278
decreased lymphocyte cell numb... 3 | 83
enlarged heart 3 | 210
increased erythrocyte cell num... 3 | 39
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
embryonic lethality prior to o... 2 | 239
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart position or ori... 1 | 1
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased spleen weight 1 | 10
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged RR interval 1 | 8
thrombocytopenia 1 | 56

Disease

Carcinoma 93 | 11,493
osteosarcoma 86 | 7,950
ovarian cancer 61 | 8,520
psoriasis 60 | 6,694
interstitial cystitis 58 | 2,312
lung cancer 57 | 4,740
lung carcinoma 53 | 2,843
Cancer 51 | 2,499
glioblastoma 48 | 5,792
tuberculosis 46 | 2,010
cutaneous lupus erythematosus 45 | 1,057
medulloblastoma, large-cell 42 | 6,241
ulcerative colitis 39 | 1,819
primary Sjogren syndrome 38 | 735
invasive ductal carcinoma 36 | 2,951
Astrocytoma, Pilocytic 31 | 3,081
adult high grade glioma 27 | 3,801
lung adenocarcinoma 27 | 2,716
subependymal giant cell astrocytoma 27 | 2,287
non-small cell lung cancer 26 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
Breast cancer 24 | 3,578
atypical teratoid / rhabdoid tumor 24 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
malignant mesothelioma 22 | 3,232
pancreatic cancer 21 | 2,398
Autosomal recessive predisposition 20 | 1,442
Rheumatoid arthritis 20 | 1,191
ependymoma 19 | 4,679
diabetes mellitus 18 | 1,728
oligodendroglioma 18 | 2,850
Kidney cancer 17 | 2,613
mucosa-associated lymphoid tissue lymphoma 17 | 484
cystic fibrosis 16 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
periodontitis 16 | 293
Multiple Sclerosis 15 | 540
Immunologic Deficiency Syndromes 14 | 113
Multiple myeloma 14 | 1,332
Schizophrenia 14 | 1,160
active Crohn's disease 14 | 922
colon cancer 14 | 1,478
ductal carcinoma in situ 14 | 1,745
group 3 medulloblastoma 14 | 4,104
head and neck cancer and chronic obstructive pulmonary disease 14 | 239
juvenile dermatomyositis 14 | 1,187
primitive neuroectodermal tumor 14 | 3,035
Anemia 13 | 365
Arthritis 13 | 290
Diarrhea 13 | 253
Liver Cirrhosis, Experimental 13 | 769
astrocytoma 13 | 1,146
group 4 medulloblastoma 13 | 1,855
Bipolar Disorder 12 | 666
Crohn's disease 12 | 321
Melanoma 12 | 711
acute myeloid leukemia 12 | 783
dermatomyositis 12 | 966
sarcoidosis 12 | 370
Asthma 11 | 385
Fever 11 | 138
Hypersensitivity reaction type II disease 11 | 253
Lymphoproliferative syndrome 11 | 58
Waldenstrons macroglobulinemia 11 | 765
astrocytic glioma 11 | 2,597
esophageal adenocarcinoma 11 | 737
Chronic Lymphocytic Leukemia 10 | 262
Severe combined immunodeficiency 10 | 51
Splenomegaly 10 | 190
active ulcerative colitis 10 | 764
breast carcinoma 10 | 1,638
chronic lymphosyte leukemia 10 | 204
gastric cancer 10 | 459
nasopharyngeal carcinoma 10 | 1,058
Common variable immunodeficiency 9 | 101
Encephalitis 9 | 64
Failure to gain weight 9 | 365
Fatigue 9 | 182
Hepatitis B 9 | 108
Pediatric failure to thrive 9 | 365
Pneumonia 9 | 174
pancreatic carcinoma 9 | 562
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pituitary cancer 9 | 1,972
primary pancreatic ductal adenocarcinoma 9 | 1,109
Hepatomegaly 8 | 285
Human immunodeficiency virus infectious disease 8 | 138
Influenza 8 | 142
Meningitis 8 | 67
Pick disease 8 | 1,894
Recurrent respiratory infections 8 | 141
Thrombocytopenia 8 | 197
pediatric high grade glioma 8 | 1,064
Allergic hypersensitivity disease 7 | 126
Atopic dermatitis 7 | 952
Chronic otitis media 7 | 52
Infantile onset 7 | 238
Kidney disease 7 | 430
Prostatic Neoplasms 7 | 495
ear infection chronic 7 | 52

Tissue

Blood and immune system 135 | 16,909
Female tissues 131 | 17,400
Skin and soft tissues 131 | 17,230
Endocrine System 130 | 18,159
Digestive Tract 129 | 17,369
Liver and Pancreas 129 | 16,750
Urinary Tract 129 | 16,678
Male tissues 127 | 17,142
Respiratory system 127 | 16,393
Cardiovascular System 118 | 15,192
Nervous System 116 | 16,725

Target Family

Non-IDG 164 | 12,091
Kinase 21 | 634
Enzyme 13 | 4,145
Ion Channel 4 | 344
Transcription Factor 4 | 1,400
GPCR 2 | 408
TF/Epigenetic 1 | 38

GO Process

adaptive immune response 209 | 209
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin heavy variable 7-4-1 IGHV7-4-1 Tdark Non-IDG 0.00000 0
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Immunoglobulin kappa variable 1D-13 IGKV1D-13 Tdark Non-IDG 0.00000 0
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor FCAMR Tbio Non-IDG -0.94276 7.33 36
Immunoglobulin lambda variable 5-39 IGLV5-39 Tdark Non-IDG 0.00000 0
Cytotoxic and regulatory T-cell molecule CRTAM Tbio Non-IDG -1.11760 15.6 131