Development Level

Tchem 23 | 1,598
Tbio 20 | 11,445
Tclin 6 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 5 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased fasted circulating g... 2 | 65
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased caudal vertebrae num... 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
pale yolk sac 1 | 25
pallor 1 | 34
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
tremors 1 | 39

Disease

Carcinoma 42 | 11,493
osteosarcoma 28 | 7,950
ovarian cancer 27 | 8,520
lung cancer 24 | 4,740
Cancer 23 | 2,499
psoriasis 22 | 6,694
glioblastoma 21 | 5,792
ependymoma 18 | 4,679
malignant mesothelioma 18 | 3,232
medulloblastoma, large-cell 18 | 6,241
Breast cancer 16 | 3,578
non-small cell lung cancer 16 | 2,890
adult high grade glioma 15 | 3,801
atypical teratoid / rhabdoid tumor 15 | 5,112
group 3 medulloblastoma 14 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
pancreatic cancer 13 | 2,398
Astrocytoma, Pilocytic 12 | 3,081
Kidney cancer 12 | 2,613
lung carcinoma 12 | 2,843
lung adenocarcinoma 11 | 2,716
astrocytic glioma 10 | 2,597
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
Hypertensive disease 9 | 292
Schizophrenia 9 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
oligodendroglioma 9 | 2,850
tuberculosis 9 | 2,010
Hypertension 8 | 396
cystic fibrosis 8 | 1,696
invasive ductal carcinoma 8 | 2,951
Liver Cirrhosis, Experimental 7 | 769
Autosomal recessive predisposition 6 | 1,442
Depressive disorder 6 | 409
Endometriosis 6 | 540
Parkinson's disease 6 | 392
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
dermatomyositis 6 | 966
ductal carcinoma in situ 6 | 1,745
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer's disease 5 | 658
Coronary artery disease 5 | 268
Kidney disease 5 | 430
Obesity 5 | 678
Pick disease 5 | 1,894
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
pancreatic carcinoma 5 | 562
ulcerative colitis 5 | 1,819
Adenoma 4 | 167
Atopic dermatitis 4 | 952
Attention deficit hyperactivity disorder 4 | 278
Autistic Disorder 4 | 364
Bipolar Disorder 4 | 666
Blastic phase chronic myeloid leukemia 4 | 58
Chronic Myelocytic Leukemia Accelerated Phase 4 | 59
Cleft Palate 4 | 271
Epilepsy 4 | 792
Osteoporosis 4 | 363
Polycystic ovary syndrome 4 | 360
Proliferative vitreoretinopathy 4 | 17
Seizures 4 | 596
Type 2 diabetes mellitus 4 | 272
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
Alcoholic Intoxication, Chronic 3 | 289
Anxiety 3 | 136
Anxiety disease 3 | 113
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Byzanthine arch palate 3 | 194
Cardiomegaly 3 | 116
Cerebrovascular disease 3 | 238
Colonic Neoplasms 3 | 142
Hernia, Inguinal 3 | 89
Hyperactive behavior 3 | 91
Lung Neoplasms 3 | 232
Lung diseases 3 | 50
Mental Depression 3 | 333
Migraine Disorders 3 | 76
Mood Disorders 3 | 184
Proteinuria 3 | 144
Recurrent infections 3 | 48
Squamous cell carcinoma 3 | 129
Substance-Related Disorders 3 | 115
Waldenstrons macroglobulinemia 3 | 765
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
interstitial lung disease 3 | 298
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Male tissues 48 | 17,142
Digestive Tract 47 | 17,369
Liver and Pancreas 47 | 16,750
Nervous System 47 | 16,725
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230
Cardiovascular System 45 | 15,192
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909

Target Family

Kinase 29 | 634
Non-IDG 16 | 12,091
GPCR 2 | 408
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

activation of protein kinase a... 50 | 50
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Serine/threonine-protein kinase OSR1 OXSR1 Tbio Kinase -0.99836 9.44 355
Serine/threonine-protein kinase 10 STK10 Tchem Kinase -2.33522 213.0 236
Targeting protein for Xklp2 TPX2 Tbio Non-IDG -2.21148 180.0 435
Serine/threonine-protein kinase Nek1 NEK1 Tchem Kinase -1.62443 47.0 85
Mitogen-activated protein kinase kinase kinase 19 MAP3K19 Tchem Kinase 0.08 1.74 33
Serine/threonine-protein kinase Nek4 NEK4 Tbio Kinase -1.15584 11.5 142
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma PPP2R3C Tbio Enzyme -1.08253 12.2 118