Development Level

Tbio 19 | 11,445
Tchem 7 | 1,598
Tclin 6 | 613

IMPC Phenotype

abnormal behavior 2 | 298
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
increased circulating alkaline... 2 | 122
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased cardiac stroke volum... 1 | 1
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 22 | 8,520
Cancer 20 | 2,499
psoriasis 19 | 6,694
Carcinoma 16 | 11,493
osteosarcoma 14 | 7,950
medulloblastoma, large-cell 13 | 6,241
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
lung cancer 12 | 4,740
Breast cancer 11 | 3,578
adult high grade glioma 11 | 3,801
diabetes mellitus 11 | 1,728
ependymoma 11 | 4,679
invasive ductal carcinoma 11 | 2,951
malignant mesothelioma 11 | 3,232
Schizophrenia 10 | 1,160
Alzheimer's disease 9 | 658
astrocytic glioma 9 | 2,597
Cardiomegaly 8 | 116
Kidney disease 8 | 430
Neurodegenerative disease 8 | 414
ductal carcinoma in situ 8 | 1,745
Astrocytoma, Pilocytic 7 | 3,081
Bipolar Disorder 7 | 666
Depressive disorder 7 | 409
Epilepsy 7 | 792
Heart disease 7 | 306
Hypertension 7 | 396
Kidney cancer 7 | 2,613
Parkinson's disease 7 | 392
breast carcinoma 7 | 1,638
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
Breast Neoplasms 6 | 445
Intellectual disability 6 | 1,016
Mammary Neoplasms 6 | 425
Obesity 6 | 678
Osteoporosis 6 | 363
Polycystic ovary syndrome 6 | 360
Vascular disease 6 | 319
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Amyotrophic lateral sclerosis 5 | 451
Arthritis 5 | 290
Asthma 5 | 385
Brain disease 5 | 96
Cerebrovascular disease 5 | 238
Hyperglycemia 5 | 137
Mental Depression 5 | 333
Mood Disorders 5 | 184
Neoplasm Invasiveness 5 | 161
Neuropathy 5 | 261
Prostatic Neoplasms 5 | 495
Seizures 5 | 596
Unipolar Depression 5 | 250
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Adult onset 4 | 82
Anemia 4 | 365
Atherosclerosis 4 | 291
Attention deficit hyperactivity disorder 4 | 278
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Coronary artery disease 4 | 268
Dyspnea 4 | 76
Fetal Growth Retardation 4 | 189
Global developmental delay 4 | 608
Heart failure 4 | 162
Hyperalgesia 4 | 83
Hyperinsulinism 4 | 133
Hypertensive disease 4 | 292
Hypothyroidism 4 | 122
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Liver Cirrhosis, Experimental 4 | 769
Liver disease 4 | 237
Lung disease 4 | 142
Major Depressive Disorder 4 | 301
Mental and motor retardation 4 | 608
Nerve Degeneration 4 | 121
Parkinson Disease 4 | 64
Peripheral vascular disease 4 | 87
Toxic encephalopathy 4 | 141
acute quadriplegic myopathy 4 | 1,158
fibroadenoma 4 | 559
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074

Tissue

Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Male tissues 31 | 17,142

Target Family

Non-IDG 19 | 12,091
Kinase 8 | 634
GPCR 3 | 408
Enzyme 2 | 4,145

GO Process

activation of protein kinase B... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
Serine/threonine-protein kinase mTOR MTOR Tclin Kinase -3.89596 7790.5 1195
3-phosphoinositide-dependent protein kinase 1 PDPK1 Tchem Kinase -2.12025 204.9 608
Protein kinase C zeta type PRKCZ Tchem Kinase -2.13834 126.9 626
Pro-neuregulin-1, membrane-bound isoform NRG1 Tbio Non-IDG -2.93105 922.4 560
Protein/nucleic acid deglycase DJ-1 PARK7 Tbio Enzyme -2.89261 835.5 625
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Insulin-like growth factor I IGF1 Tbio Non-IDG -4.32790 22748.0 913