Development Level

Tclin 9 | 613
Tbio 8 | 11,445
Tchem 8 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal seminal vesicle morph... 1 | 114
abnormal vocalization 1 | 21
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 23 | 11,493
psoriasis 17 | 6,694
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
lung cancer 11 | 4,740
Cancer 10 | 2,499
invasive ductal carcinoma 10 | 2,951
medulloblastoma, large-cell 10 | 6,241
ovarian cancer 10 | 8,520
malignant mesothelioma 9 | 3,232
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
lung adenocarcinoma 8 | 2,716
Schizophrenia 7 | 1,160
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
subependymal giant cell astrocytoma 7 | 2,287
Hypertension 6 | 396
Obesity 6 | 678
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
Asthma 5 | 385
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Heart disease 5 | 306
Hypertensive disease 5 | 292
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
cutaneous lupus erythematosus 5 | 1,057
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Bipolar Disorder 4 | 666
Craniofacial Abnormalities 4 | 151
Depressive disorder 4 | 409
Heart failure 4 | 162
Kidney disease 4 | 430
Major Depressive Disorder 4 | 301
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pituitary cancer 4 | 1,972
Anemia 3 | 365
Arthritis 3 | 290
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Attention deficit hyperactivity disorder 3 | 278
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Diabetes Mellitus, Experimental 3 | 108
Essential Hypertension 3 | 94
Kidney cancer 3 | 2,613
Mental Depression 3 | 333
Multiple Sclerosis 3 | 540
Pick disease 3 | 1,894
Seizures 3 | 596
Unipolar Depression 3 | 250
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
pulmonary arterial hypertension 3 | 75
tuberculosis 3 | 2,010
Adenoma 2 | 167
Alcoholic Intoxication, Chronic 2 | 289
Allergic rhinitis 2 | 94
Cardiovascular Diseases 2 | 59
Dermatitis 2 | 157
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease Progression 2 | 136
Down syndrome 2 | 499
Endometriosis 2 | 540
Epilepsy 2 | 792
Focal glomerulosclerosis 2 | 37
Glomerulosclerosis, Focal Segmental 2 | 28
Hypersensitivity reaction type II disease 2 | 253
IGA Glomerulonephritis 2 | 50
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Lung disease 2 | 142
Melanoma 2 | 711
Mood Disorders 2 | 184
Myocardial Ischemia 2 | 169
Parkinson's disease 2 | 392
Peripheral vascular disease 2 | 87
Reperfusion Injury 2 | 86
Skin cancer 2 | 469
Urticaria 2 | 67
Vascular disease 2 | 319
Vomiting 2 | 116
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
esophageal adenocarcinoma 2 | 737
head and neck cancer 2 | 271
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064

Tissue

Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Skin and soft tissues 25 | 17,230
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Urinary Tract 24 | 16,678
Blood and immune system 23 | 16,909
Female tissues 23 | 17,400
Respiratory system 23 | 16,393
Cardiovascular System 22 | 15,192
Nervous System 22 | 16,725

Target Family

GPCR 13 | 408
Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Kinase 3 | 634

GO Process

activation of phospholipase C ... 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rho GTPase-activating protein 6 ARHGAP6 Tbio Enzyme -0.85601 8.06 45
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
5-hydroxytryptamine receptor 2A HTR2A Tclin GPCR -3.33563 2152.8 231
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Endothelin-1 receptor EDNRA Tclin GPCR -2.86513 644.6 259
Lysophosphatidic acid receptor 2 LPAR2 Tchem GPCR -1.98394 89.3 265