Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased bone mineral content 1 | 151
decreased circulating insulin ... 1 | 76
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
small superior vagus ganglion 1 | 74

Disease

Cancer 11 | 2,499
ovarian cancer 9 | 8,520
psoriasis 9 | 6,694
Carcinoma 8 | 11,493
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
Astrocytoma, Pilocytic 6 | 3,081
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
malignant mesothelioma 6 | 3,232
Prostatic Neoplasms 5 | 495
cutaneous lupus erythematosus 5 | 1,057
ependymoma 5 | 4,679
tuberculosis 5 | 2,010
Arthritis 4 | 290
Autoimmune lymphoproliferative syndrome 4 | 11
Hypersensitivity reaction type II disease 4 | 253
Multiple Sclerosis 4 | 540
Rheumatoid arthritis 4 | 1,191
Splenomegaly 4 | 190
Vascular disease 4 | 319
adult high grade glioma 4 | 3,801
gastric carcinoma 4 | 807
lung carcinoma 4 | 2,843
subependymal giant cell astrocytoma 4 | 2,287
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Cerebral Hemorrhage 3 | 42
Colonic Neoplasms 3 | 142
Esophageal Neoplasms 3 | 69
Fatigue 3 | 182
Hepatomegaly 3 | 285
Kidney cancer 3 | 2,613
Leukemia 3 | 104
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Liver disease 3 | 237
Lung Neoplasms 3 | 232
Mammary Neoplasms 3 | 425
Systemic lupus erythematosus 3 | 194
Vasculitis 3 | 80
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
medulloblastoma, large-cell 3 | 6,241
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
ulcerative colitis 3 | 1,819
Abdominal Pain 2 | 98
Abortion, Spontaneous 2 | 109
Adenocarcinoma 2 | 122
Anemia 2 | 365
Arthralgia 2 | 90
Autoimmune thrombocytopenia 2 | 22
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Non-Small-Cell Lung 2 | 107
Cardiomyopathies 2 | 110
Cardiomyopathy, Dilated 2 | 83
Chest Pain 2 | 38
Colorectal Neoplasms 2 | 243
Craniofacial Abnormalities 2 | 151
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease of anatomical entity 2 | 32
Ecchymosis 2 | 66
Eosinophilia 2 | 28
Fever 2 | 138
Gaucher disease type 3 2 | 67
Idiopathic thrombocytopenia 2 | 22
Immune thrombocytopenic purpura 2 | 24
Increased IgM levels 2 | 16
Increased tendency to bruise 2 | 66
Inflammatory bowel disease 2 | 151
Liver Cirrhosis 2 | 181
Liver Dysfunction 2 | 99
Liver Failure, Acute 2 | 29
Liver carcinoma 2 | 240
Lymphoma, T-Cell, Cutaneous 2 | 22
Melanoma 2 | 711
Myocardial Infarction 2 | 151
Neoplasm Metastasis 2 | 168
Non-alcoholic Fatty Liver Disease 2 | 42
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pneumonia 2 | 174
Polycystic ovary syndrome 2 | 360
Sensorineural Hearing Loss (disorder) 2 | 284
Somatic mutation 2 | 61
Spontaneous abortion 2 | 113
Squamous cell carcinoma of the head and neck 2 | 29
Thrombocytopenia 2 | 197
Urticaria 2 | 67
Uterine Cervical Neoplasms 2 | 26
Venous Thrombosis 2 | 47
non-small cell lung carcinoma 2 | 317

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 9 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

activation of cysteine-type en... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526
Tumor necrosis factor ligand superfamily member 6 FASLG Tbio Non-IDG -3.53551 3585.2 953
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.90485 75.1 549
Tumor necrosis factor receptor type 1-associated DEATH domain protein TRADD Tbio Non-IDG -2.04155 97.1 383
Apoptosis regulator BAX BAX Tchem Non-IDG -2.57834 248.4 1395
Tumor necrosis factor receptor superfamily member 10A TNFRSF10A Tchem Non-IDG -3.41373 2664.2 812