Development Level

Tbio 51 | 11,445
Tchem 21 | 1,598
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal lens morphology 3 | 81
abnormal bone structure 2 | 187
abnormal gait 2 | 69
cataract 2 | 92
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
abnormal behavior 1 | 298
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal eyelid morphology 1 | 7
abnormal kidney morphology 1 | 65
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating free fat... 1 | 20
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
limb grasping 1 | 41
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

osteosarcoma 48 | 7,950
ovarian cancer 48 | 8,520
Cancer 45 | 2,499
Carcinoma 43 | 11,493
psoriasis 39 | 6,694
lung cancer 34 | 4,740
glioblastoma 32 | 5,792
medulloblastoma, large-cell 32 | 6,241
malignant mesothelioma 30 | 3,232
atypical teratoid / rhabdoid tumor 27 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
pancreatic cancer 25 | 2,398
group 3 medulloblastoma 23 | 4,104
tuberculosis 23 | 2,010
ependymoma 21 | 4,679
ulcerative colitis 20 | 1,819
Astrocytoma, Pilocytic 19 | 3,081
adult high grade glioma 19 | 3,801
lung carcinoma 19 | 2,843
Breast cancer 18 | 3,578
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
primitive neuroectodermal tumor 18 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
non-small cell lung cancer 17 | 2,890
oligodendroglioma 17 | 2,850
diabetes mellitus 16 | 1,728
invasive ductal carcinoma 16 | 2,951
pituitary cancer 16 | 1,972
Autosomal recessive predisposition 14 | 1,442
cutaneous lupus erythematosus 14 | 1,057
cystic fibrosis 14 | 1,696
lung adenocarcinoma 14 | 2,716
subependymal giant cell astrocytoma 14 | 2,287
Kidney cancer 12 | 2,613
interstitial cystitis 12 | 2,312
Prostatic Neoplasms 11 | 495
adrenocortical carcinoma 11 | 1,428
breast carcinoma 11 | 1,638
pediatric high grade glioma 11 | 1,064
primary pancreatic ductal adenocarcinoma 11 | 1,109
Bipolar Disorder 10 | 666
Hypersensitivity reaction type II disease 10 | 253
Multiple Sclerosis 10 | 540
Multiple myeloma 10 | 1,332
Renal Cell Carcinoma 10 | 214
Schizophrenia 10 | 1,160
dermatomyositis 10 | 966
nasopharyngeal carcinoma 10 | 1,058
Alzheimer's disease 9 | 658
Arthritis 9 | 290
Atopic dermatitis 9 | 952
Nerve Degeneration 9 | 121
Rheumatoid arthritis 9 | 1,191
Stomach Neoplasms 9 | 300
Waldenstrons macroglobulinemia 9 | 765
astrocytic glioma 9 | 2,597
colon cancer 9 | 1,478
esophageal adenocarcinoma 9 | 737
gastric carcinoma 9 | 807
Adenocarcinoma 8 | 122
Atherosclerosis 8 | 291
Inflammation 8 | 120
Intellectual disability 8 | 1,016
Liver carcinoma 8 | 240
Melanoma 8 | 711
Neurodegenerative disease 8 | 414
Parkinson's disease 8 | 392
Pick disease 8 | 1,894
Toxic encephalopathy 8 | 141
active ulcerative colitis 8 | 764
hepatocellular carcinoma 8 | 547
mucosa-associated lymphoid tissue lymphoma 8 | 484
pancreatic carcinoma 8 | 562
primary Sjogren syndrome 8 | 735
Amyotrophic lateral sclerosis 7 | 451
Carcinoma, Hepatocellular 7 | 228
Carcinoma, Renal Cell 7 | 124
Cerebrovascular disease 7 | 238
Colorectal Neoplasms 7 | 243
Depressive disorder 7 | 409
Kidney disease 7 | 430
Liver Cirrhosis, Experimental 7 | 769
Liver disease 7 | 237
Lung Neoplasms 7 | 232
Vascular disease 7 | 319
active Crohn's disease 7 | 922
acute quadriplegic myopathy 7 | 1,158
atypical teratoid/rhabdoid tumor 7 | 357
ductal carcinoma in situ 7 | 1,745
gastric cancer 7 | 459
Chronic Lymphocytic Leukemia 6 | 262
Coronary artery disease 6 | 268
Crohn's disease 6 | 321
Diabetes Mellitus, Type 2 6 | 142
Inflammatory bowel disease 6 | 151
Liver neoplasms 6 | 130
Seizures 6 | 596
Status Epilepticus 6 | 98
astrocytoma 6 | 1,146

Tissue

Digestive Tract 78 | 17,369
Endocrine System 78 | 18,159
Female tissues 78 | 17,400
Liver and Pancreas 78 | 16,750
Male tissues 78 | 17,142
Skin and soft tissues 78 | 17,230
Urinary Tract 78 | 16,678
Blood and immune system 77 | 16,909
Nervous System 77 | 16,725
Respiratory system 77 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 59 | 12,091
Enzyme 10 | 4,145
Kinase 5 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

activation of cysteine-type en... 80 | 80
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
CASP8-associated protein 2 CASP8AP2 Tbio Non-IDG 0.00000 0
Interferon alpha-inducible protein 27, mitochondrial IFI27 Tbio Non-IDG -1.51419 33.3 0
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Death domain-containing protein CRADD CRADD Tbio Non-IDG -1.34614 23.0 400
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Mitochondrial carrier homolog 1 MTCH1 Tbio Non-IDG -0.76817 7.07 103
Protein BEX3 BEX3 Tbio Non-IDG -1.94670 88.1 199