Development Level

Tbio 8 | 11,651
Tchem 3 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased bone mineral content 1 | 151
decreased circulating potassiu... 1 | 20
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased circulating potassiu... 1 | 29
small superior vagus ganglion 1 | 74

Disease

glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Cancer 6 | 2,499
Carcinoma 6 | 11,493
osteosarcoma 6 | 7,950
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
tuberculosis 5 | 2,010
Breast cancer 4 | 3,578
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
group 4 medulloblastoma 4 | 1,855
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
primitive neuroectodermal tumor 4 | 3,035
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Duchenne muscular dystrophy 3 | 601
Pick disease 3 | 1,894
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
Autoimmune lymphoproliferative syndrome 2 | 11
Becker muscular dystrophy 2 | 191
Down syndrome 2 | 499
Kidney cancer 2 | 2,613
Rheumatoid arthritis 2 | 1,191
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
Adenocarcinoma 1 | 122
Breast Neoplasms 1 | 445
Cerebral Hemorrhage 1 | 42
Colorectal Neoplasms 1 | 243
Congenital anomaly of face 1 | 56
Conn's syndrome 1 | 22
Craniofacial Abnormalities 1 | 151
Decreased liver function 1 | 24
Degenerative brain disorder 1 | 100
Distortion of face 1 | 46
Downward slant of palpebral fissure 1 | 158
Dysmorphic facies 1 | 46
Encephalopathies 1 | 43
Esophageal Neoplasms 1 | 69
Fetal alcohol spectrum disorder 1 | 7
Fragile X syndrome 1 | 34
Funny looking face 1 | 46
Gaucher disease type 1 1 | 180
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Large nose 1 | 23
Liver dysfunction, mild 1 | 24
Lymphadenopathy 1 | 62
Lymphoid leukemia 1 | 160
Mammary Neoplasms 1 | 425
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Pneumonia 1 | 174
Reactive airway disease 1 | 21
Recurrent infections 1 | 48
Retrognathia 1 | 54
Sensorineural Hearing Loss (disorder) 1 | 284
Somatic mutation 1 | 61
Spina bifida occulta 1 | 19
Supratentorial atrophy 1 | 94
Systemic lupus erythematosus 1 | 194
Telangiectasis 1 | 36
Testicular cancer 1 | 25
Uterine Cervical Neoplasm 1 | 25
Uterine Cervical Neoplasms 1 | 26
facial deformity 1 | 46
fascioscapulohumeral muscular dystrophy 1 | 100
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

GO Process

activation of cysteine-type en... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aspartyl/asparaginyl beta-hydroxylase ASPH Tbio Enzyme -2.70558 505.4 235
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.03990 107.3 474
Cell death activator CIDE-B CIDEB Tbio Non-IDG -1.29216 23.6 249
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Cytoplasmic FMR1-interacting protein 2 CYFIP2 Tbio Non-IDG -1.50813 23.0 99
TBC1 domain family member 10A TBC1D10A Tbio Non-IDG -0.65759 0.00000 99
p53 apoptosis effector related to PMP-22 PERP Tbio Non-IDG -2.35251 224.2 191
Gamma-interferon-inducible protein 16 IFI16 Tbio Non-IDG -1.96972 112.7 246
Bcl-2 homologous antagonist/killer BAK1 Tbio Non-IDG -2.29199 175.9 554