Development Level

Tbio 13 | 11,445
Tchem 5 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal lens morphology 1 | 81
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148

Disease

Carcinoma 14 | 11,493
ovarian cancer 13 | 8,520
osteosarcoma 10 | 7,950
glioblastoma 9 | 5,792
Cancer 8 | 2,499
lung cancer 8 | 4,740
atypical teratoid / rhabdoid tumor 7 | 5,112
psoriasis 7 | 6,694
medulloblastoma, large-cell 6 | 6,241
Astrocytoma, Pilocytic 5 | 3,081
acute quadriplegic myopathy 5 | 1,158
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
Arthritis 4 | 290
Hypersensitivity reaction type II disease 4 | 253
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
ependymoma 4 | 4,679
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Breast cancer 3 | 3,578
Multiple Sclerosis 3 | 540
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Age related macular degeneration 2 | 72
Alzheimer's disease 2 | 658
Anemia 2 | 365
Arthritis, Rheumatoid 2 | 174
Asthma 2 | 385
Autosomal recessive predisposition 2 | 1,442
Coronary artery disease 2 | 268
Fatigue 2 | 182
Kidney cancer 2 | 2,613
Liver disease 2 | 237
Lung disease 2 | 142
Lymphoma 2 | 81
Pelvic inflammatory disease 2 | 21
Schizophrenia 2 | 1,160
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
interstitial cystitis 2 | 2,312
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
Agenesis of teeth 1 | 21
Arthropathy 1 | 43
B-Cell Lymphomas 1 | 12
Biliary cirrhosis 1 | 45
Carcinoma, squamous cell of head and neck 1 | 31
Cholestasis, Extrahepatic 1 | 25
Congenital sensorineural hearing loss 1 | 12
Diffuse large B-cell lymphoma 1 | 39
Drug allergy 1 | 36
Familial primary gastric lymphoma 1 | 4
Felty's syndrome 1 | 7
Gastric lymphoma 1 | 7
Gastrointestinal stromal tumor 1 | 62
Gastrointestinal system disease 1 | 54
Hamman-Rich syndrome 1 | 34
Hanot's cirrhosis 1 | 8
Herpes simplex 1 | 18
Hypotension, Orthostatic 1 | 18
Increased hepatocellular carcinoma risk 1 | 27
Increased incidence of hepatocellular carcinoma 1 | 27
Infiltrate of lung 1 | 17
Inflammatory Bowel Diseases 1 | 35
Leprosy 1 | 73
Liver Neoplasms, Experimental 1 | 59
MALT lymphoma 1 | 6
Mitral regurgitation, mild 1 | 32
Mulibrey nanism 1 | 13
Mumps 1 | 10
Nausea 1 | 20
Neoplasms 1 | 63
Pancreatic Neuroendocrine Tumor 1 | 45
Psoriatic arthritis 1 | 86
Reduced number of teeth 1 | 21
Short thumb terminal phalanx 1 | 5
Squamous cell carcinoma of the head and neck 1 | 29

Tissue

Blood and immune system 18 | 16,909
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Skin and soft tissues 18 | 17,230
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Respiratory system 17 | 16,393
Urinary Tract 17 | 16,678

Target Family

Non-IDG 11 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

activation of NF-kappaB-induci... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TNF receptor-associated factor 4 TRAF4 Tbio Non-IDG -1.67380 54.4 234
Caspase recruitment domain-containing protein 10 CARD10 Tbio Enzyme -1.49849 26.7 177
Caspase recruitment domain-containing protein 14 CARD14 Tbio Enzyme -1.63054 42.9 127
Toll-like receptor 6 TLR6 Tbio Non-IDG -2.18033 129.1 692
COP9 signalosome complex subunit 8 COPS8 Tbio Non-IDG -1.20410 15.8 166
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.82180 732.9 299
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Toll-like receptor 3 TLR3 Tbio Non-IDG -3.09062 1260.4 874
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.90485 75.1 549