Development Level

Tbio 48 | 11,651
Tchem 41 | 1,388
Tclin 15 | 612
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 4 | 499
decreased circulating insulin ... 3 | 76
decreased total body fat amoun... 3 | 207
increased fasted circulating g... 3 | 76
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal optic disc morphology 2 | 10
cataract 2 | 92
decreased threshold for audito... 2 | 26
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
abnormal cecum morphology 1 | 7
abnormal clavicle morphology 1 | 6
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
female infertility 1 | 60
fused cornea and lens 1 | 5
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
limb grasping 1 | 41
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 65 | 11,493
ovarian cancer 59 | 8,520
osteosarcoma 56 | 7,950
psoriasis 54 | 6,694
Cancer 53 | 2,499
glioblastoma 51 | 5,792
medulloblastoma, large-cell 46 | 6,241
ependymoma 42 | 4,679
lung cancer 39 | 4,740
atypical teratoid / rhabdoid tumor 38 | 5,112
non-small cell lung cancer 32 | 2,890
invasive ductal carcinoma 30 | 2,951
Breast cancer 29 | 3,578
Astrocytoma, Pilocytic 28 | 3,081
astrocytic glioma 28 | 2,597
malignant mesothelioma 28 | 3,232
ulcerative colitis 28 | 1,819
adult high grade glioma 27 | 3,801
lung adenocarcinoma 27 | 2,716
lung carcinoma 27 | 2,843
pancreatic cancer 27 | 2,398
Schizophrenia 26 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
group 3 medulloblastoma 24 | 4,104
interstitial cystitis 24 | 2,312
oligodendroglioma 23 | 2,850
tuberculosis 23 | 2,010
diabetes mellitus 22 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
subependymal giant cell astrocytoma 18 | 2,287
Bipolar Disorder 17 | 666
group 4 medulloblastoma 17 | 1,855
pituitary cancer 17 | 1,972
primitive neuroectodermal tumor 17 | 3,035
adrenocortical carcinoma 16 | 1,428
cystic fibrosis 16 | 1,696
ductal carcinoma in situ 16 | 1,745
Alzheimer's disease 15 | 658
Autosomal recessive predisposition 15 | 1,442
Depressive disorder 15 | 409
Kidney cancer 15 | 2,613
Liver Cirrhosis, Experimental 15 | 769
Rheumatoid arthritis 15 | 1,191
Vascular disease 15 | 319
colon cancer 15 | 1,478
breast carcinoma 14 | 1,638
juvenile dermatomyositis 14 | 1,187
Arthritis 13 | 290
Breast Neoplasms 13 | 445
Multiple myeloma 13 | 1,332
dermatomyositis 13 | 966
Mammary Neoplasms 12 | 425
Mental Depression 12 | 333
Nerve Degeneration 12 | 121
Pick disease 12 | 1,894
Short stature 12 | 531
primary pancreatic ductal adenocarcinoma 12 | 1,109
Intellectual disability 11 | 1,016
Kidney disease 11 | 430
Lung Neoplasms 11 | 232
Major Depressive Disorder 11 | 301
Neoplasm Invasiveness 11 | 161
Neoplasm Metastasis 11 | 168
Parkinson's disease 11 | 392
Prostatic Neoplasms 11 | 495
Pulmonary Fibrosis 11 | 106
Unipolar Depression 11 | 250
acute myeloid leukemia 11 | 783
astrocytoma 11 | 1,146
esophageal adenocarcinoma 11 | 737
pediatric high grade glioma 11 | 1,064
Coronary artery disease 10 | 268
Down syndrome 10 | 499
Epilepsy 10 | 792
Heart disease 10 | 306
Melanoma 10 | 711
Obesity 10 | 678
Reperfusion Injury 10 | 86
Toxic encephalopathy 10 | 141
cutaneous lupus erythematosus 10 | 1,057
pancreatic carcinoma 10 | 562
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Asthma 9 | 385
Cleft Palate 9 | 271
Cognitive delay 9 | 608
Dull intelligence 9 | 645
Endometriosis 9 | 540
Global developmental delay 9 | 608
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental and motor retardation 9 | 608
Mental deficiency 9 | 645
Myocardial Ischemia 9 | 169
Orbital separation excessive 9 | 244
Poor school performance 9 | 645
Waldenstrons macroglobulinemia 9 | 765
mucosa-associated lymphoid tissue lymphoma 9 | 484
nasopharyngeal carcinoma 9 | 1,058
non primary Sjogren syndrome sicca 9 | 891

Tissue

Endocrine System 107 | 18,159
Female tissues 106 | 17,400
Blood and immune system 105 | 16,909
Digestive Tract 105 | 17,369
Liver and Pancreas 104 | 16,750
Nervous System 104 | 16,725
Skin and soft tissues 104 | 17,230
Urinary Tract 104 | 16,678
Male tissues 103 | 17,142
Respiratory system 101 | 16,393
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 49 | 12,091
Kinase 28 | 634
Enzyme 16 | 4,145
GPCR 11 | 408
Ion Channel 2 | 344
Transcription Factor 1 | 1,400

GO Process

activation of MAPK activity 107 | 107
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Tumor necrosis factor TNF Tclin Non-IDG -4.71806 50345.6 2958
Amyloid-beta A4 protein APP Tchem Non-IDG -3.99225 9853.3 2781
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Cyclin-dependent kinase 1 CDK1 Tchem Kinase -3.28086 1790.3 1933
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Mitogen-activated protein kinase 14 MAPK14 Tchem Kinase -3.36007 2240.8 1574
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.81927 6905.8 1289