Development Level

Tchem 44 | 1,890
Tbio 40 | 10,625
Tclin 14 | 602
Tdark 3 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
decreased circulating insulin ... 3 | 75
abnormal bone structure 2 | 131
decreased bone mineral content 2 | 157
decreased kidney weight 2 | 7
decreased lumbar vertebrae num... 2 | 62
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased circulating HDL chol... 2 | 63
increased fasted circulating g... 2 | 68
increased mean corpuscular hem... 2 | 93
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
dilated heart left ventricle 1 | 10
enlarged heart 1 | 111
female infertility 1 | 34
hydrops fetalis 1 | 22
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
male infertility 1 | 62
narrow eye opening 1 | 15
polydactyly 1 | 22
short tibia 1 | 82
thrombocytopenia 1 | 46

Disease

ovarian cancer 55 | 8,484
osteosarcoma 53 | 7,933
Cancer 51 | 2,346
psoriasis 50 | 6,685
glioblastoma 49 | 5,572
medulloblastoma, large-cell 44 | 6,234
lung cancer 36 | 4,466
atypical teratoid / rhabdoid tumor 31 | 4,369
pilocytic astrocytoma 30 | 3,086
ulcerative colitis 30 | 2,087
non-small cell lung cancer 29 | 2,798
invasive ductal carcinoma 28 | 2,950
pancreatic cancer 27 | 2,300
lung adenocarcinoma 26 | 2,713
lung carcinoma 26 | 2,844
malignant mesothelioma 26 | 3,162
pediatric high grade glioma 26 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
Breast cancer 23 | 3,094
interstitial cystitis 23 | 2,299
ependymoma 22 | 2,514
astrocytic glioma 21 | 2,241
diabetes mellitus 21 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
Carcinoma 20 | 2,147
oligodendroglioma 20 | 2,849
tuberculosis 19 | 1,557
group 3 medulloblastoma 17 | 2,254
pituitary cancer 17 | 1,972
subependymal giant cell astrocytoma 17 | 2,287
adrenocortical carcinoma 16 | 1,427
group 4 medulloblastoma 16 | 1,875
primitive neuroectodermal tumor 16 | 3,031
colon cancer 15 | 1,475
cystic fibrosis 15 | 1,665
ductal carcinoma in situ 15 | 1,745
posterior fossa group A ependymoma 15 | 1,511
Alzheimer's disease 14 | 644
Rheumatoid Arthritis 14 | 1,160
breast carcinoma 14 | 1,614
astrocytoma 13 | 1,493
juvenile dermatomyositis 13 | 1,189
Mammary Neoplasms 12 | 410
Multiple myeloma 12 | 1,327
Vascular disease 12 | 281
posterior fossa group B ependymoma 12 | 1,530
primary pancreatic ductal adenocarcinoma 12 | 1,271
Arthritis 11 | 248
Down syndrome 11 | 548
Nerve Degeneration 11 | 73
Obesity 11 | 616
Prostatic Neoplasms 11 | 471
adult high grade glioma 11 | 2,148
cutaneous lupus erythematosus 11 | 1,056
dermatomyositis 11 | 933
esophageal adenocarcinoma 11 | 737
medulloblastoma 11 | 1,524
Heart disease 10 | 279
Kidney disease 10 | 396
Pick disease 10 | 1,893
Pulmonary Fibrosis 10 | 66
Schizophrenia 10 | 501
acute myeloid leukemia 10 | 780
pancreatic carcinoma 10 | 567
Asthma 9 | 349
Atherosclerosis 9 | 275
Atopic dermatitis 9 | 944
Bipolar Disorder 9 | 266
Endometriosis 9 | 535
Myocardial Ischemia 9 | 169
Neoplasm Metastasis 9 | 138
Reperfusion Injury 9 | 84
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
Cleft palate 8 | 125
Hyperalgesia 8 | 71
Lung Neoplasms 8 | 171
Neoplasm Invasiveness 8 | 127
Parkinson's disease 8 | 364
Stomach Neoplasms 8 | 282
Toxic encephalopathy 8 | 131
gastric carcinoma 8 | 832
hepatocellular carcinoma 8 | 532
mucosa-associated lymphoid tissue lymphoma 8 | 480
Brain Ischemia 7 | 87
Cardiomyopathies 7 | 90
Coronary artery disease 7 | 240
Lung disease 7 | 132
Melanoma 7 | 261
Multiple Sclerosis 7 | 498
Polycystic Ovary Syndrome 7 | 332
Waldenstrons macroglobulinemia 7 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
inflammatory breast cancer 7 | 404
nasopharyngeal carcinoma 7 | 1,056
non primary Sjogren syndrome sicca 7 | 840
spina bifida 7 | 1,064
Duchenne muscular dystrophy 6 | 602
acute quadriplegic myopathy 6 | 1,157
sonic hedgehog group medulloblastoma 6 | 1,482

Tissue

Blood and immune system 101 | 17,995
Endocrine System 101 | 18,512
Female tissues 101 | 18,647
Liver and Pancreas 101 | 18,136
Nervous System 101 | 18,561
Respiratory system 101 | 17,484
Urinary Tract 101 | 18,444
Cardiovascular System 100 | 17,958
Digestive Tract 100 | 18,473
Male tissues 100 | 17,969
Skin and soft tissues 100 | 18,115

Target Family

Non-IDG 44 | 11,971
Kinase 29 | 634
Enzyme 15 | 4,146
GPCR 10 | 406
Ion Channel 2 | 341
Transcription Factor 1 | 1,400

GO Process

activation of MAPK activity 101 | 101
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Beta-arrestin-1 ARRB1 Tchem Non-IDG -2.54226 366.3 416
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.83055 69.0 145
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.59556 4267.5 575
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -3.97848 10115.4 658