Development Level

Tchem 17 | 1,598
Tbio 16 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal bone structure 2 | 187
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased mean platelet volume 1 | 45
thin ventricular wall 1 | 24

Disease

Carcinoma 29 | 11,493
ovarian cancer 18 | 8,520
osteosarcoma 17 | 7,950
Cancer 16 | 2,499
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
lung cancer 12 | 4,740
Kidney cancer 11 | 2,613
medulloblastoma, large-cell 11 | 6,241
ependymoma 10 | 4,679
tuberculosis 10 | 2,010
Astrocytoma, Pilocytic 9 | 3,081
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pancreatic cancer 8 | 2,398
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
Pick disease 6 | 1,894
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
Chronic Myelocytic Leukemia Accelerated Phase 5 | 59
Rheumatoid arthritis 5 | 1,191
adrenocortical carcinoma 5 | 1,428
cystic fibrosis 5 | 1,696
group 3 medulloblastoma 5 | 4,104
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819
Asthma 4 | 385
Blastic phase chronic myeloid leukemia 4 | 58
Breast cancer 4 | 3,578
Lung Neoplasms 4 | 232
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
group 4 medulloblastoma 4 | 1,855
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
Acute myeloid leukemia, disease 3 | 30
Aggressive systemic mastocytosis 3 | 20
Allergic hypersensitivity disease 3 | 126
Cataract 7 3 | 32
Chronic Lymphocytic Leukemia 3 | 262
Dental caries 3 | 164
Down syndrome 3 | 499
Hepatomegaly 3 | 285
Intellectual disability 3 | 1,016
Mast cell leukemia 3 | 13
Melanoma 3 | 711
Osteoporosis 3 | 363
Renal Cell Carcinoma 3 | 214
Schizophrenia 3 | 1,160
Splenomegaly 3 | 190
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
gastric carcinoma 3 | 807
pediatric high grade glioma 3 | 1,064
sarcoidosis 3 | 370
Allergic rhinitis 2 | 94
Anemia 2 | 365
Arthritis 2 | 290
Atopic dermatitis 2 | 952
Broad flat nasal bridge 2 | 236
Diarrhea 2 | 253
Epilepsy 2 | 792
Hypersensitivity 2 | 63
Hypertension 2 | 396
Infertility 2 | 188
Long philtrum 2 | 137
Low Vision 2 | 174
Microcephaly 2 | 166
Multiple Sclerosis 2 | 540
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Urticaria 2 | 67
Vascular disease 2 | 319
Visual Impairment 2 | 174
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
head and neck cancer 2 | 271
hereditary spastic paraplegia 2 | 318
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Nervous System 32 | 16,725
Cardiovascular System 31 | 15,192

Target Family

Kinase 17 | 634
Non-IDG 13 | 12,091
Enzyme 5 | 4,145

GO Process

activation of JUN kinase activ... 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 Tchem Kinase -1.76819 60.5 0
Mitogen-activated protein kinase kinase kinase 10 MAP3K10 Tchem Kinase -1.20048 15.1 221
Mitogen-activated protein kinase kinase kinase 2 MAP3K2 Tchem Kinase -1.47034 26.6 199
Mitogen-activated protein kinase kinase kinase kinase 2 MAP4K2 Tchem Kinase -1.60423 35.3 193
Mitogen-activated protein kinase kinase kinase 21 MAP3K21 Tdark Kinase -0.42420 4.24 174
Mitogen-activated protein kinase kinase kinase 20 MAP3K20 Tchem Kinase -1.18567 14.9 215
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Protein Wnt-7b WNT7B Tbio Non-IDG -1.76807 52.2 46
DNA excision repair protein ERCC-6 ERCC6 Tbio Non-IDG -2.31776 361.5 163
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.66356 3766.3 513