Development Level

Tbio 59 | 11,445
Tdark 25 | 6,588
Tchem 5 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
embryonic growth retardation 2 | 106
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
pale yolk sac 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small seminal vesicle 1 | 10
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 63 | 11,493
ovarian cancer 42 | 8,520
osteosarcoma 41 | 7,950
psoriasis 34 | 6,694
medulloblastoma, large-cell 28 | 6,241
glioblastoma 27 | 5,792
atypical teratoid / rhabdoid tumor 26 | 5,112
ependymoma 23 | 4,679
Kidney cancer 21 | 2,613
adult high grade glioma 21 | 3,801
lung cancer 19 | 4,740
Cancer 18 | 2,499
Breast cancer 17 | 3,578
group 3 medulloblastoma 17 | 4,104
invasive ductal carcinoma 17 | 2,951
oligodendroglioma 17 | 2,850
lung carcinoma 14 | 2,843
malignant mesothelioma 14 | 3,232
tuberculosis 14 | 2,010
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung adenocarcinoma 13 | 2,716
non-small cell lung cancer 13 | 2,890
Astrocytoma, Pilocytic 12 | 3,081
interstitial cystitis 12 | 2,312
subependymal giant cell astrocytoma 12 | 2,287
Pick disease 11 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
primitive neuroectodermal tumor 11 | 3,035
astrocytoma 9 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
ductal carcinoma in situ 8 | 1,745
pancreatic cancer 8 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
ulcerative colitis 8 | 1,819
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
Bipolar Disorder 6 | 666
Rheumatoid arthritis 6 | 1,191
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
cutaneous lupus erythematosus 6 | 1,057
diabetes mellitus 6 | 1,728
primary Sjogren syndrome 6 | 735
sonic hedgehog group medulloblastoma 6 | 467
Atopic dermatitis 5 | 952
Liver Cirrhosis, Experimental 5 | 769
Multiple Sclerosis 5 | 540
active Crohn's disease 5 | 922
pituitary cancer 5 | 1,972
Endometriosis 4 | 540
Intellectual disability 4 | 1,016
Obesity 4 | 678
Schizophrenia 4 | 1,160
Status Epilepticus 4 | 98
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
Alzheimer's disease 3 | 658
Cardiovascular system disease 3 | 246
Chronic Lymphocytic Leukemia 3 | 262
Cognitive delay 3 | 608
Crohn's disease 3 | 321
Dull intelligence 3 | 645
Epilepsy 3 | 792
Glaucoma 3 | 239
Global developmental delay 3 | 608
Hypersensitivity reaction type II disease 3 | 253
Liver cancer 3 | 604
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Mood Disorders 3 | 184
Neuropathy 3 | 261
Poor school performance 3 | 645
Type 2 diabetes mellitus 3 | 272
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
gastric carcinoma 3 | 807
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
sarcoidosis 3 | 370
spina bifida 3 | 1,074
tuberculosis and treatment for 3 months 3 | 179
Arthritis, Juvenile 2 | 126
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Juvenile arthritis 2 | 126
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 559
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676

Tissue

Endocrine System 90 | 18,159
Blood and immune system 87 | 16,909
Digestive Tract 84 | 17,369
Male tissues 84 | 17,142
Skin and soft tissues 84 | 17,230
Urinary Tract 84 | 16,678
Female tissues 83 | 17,400
Liver and Pancreas 83 | 16,750
Respiratory system 82 | 16,393
Nervous System 79 | 16,725
Cardiovascular System 78 | 15,192

Target Family

Non-IDG 69 | 12,091
Enzyme 11 | 4,145
Kinase 7 | 634
GPCR 2 | 408
Transcription Factor 1 | 1,400

GO Process

activation of GTPase activity 90 | 90
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
TBC1 domain family member 13 TBC1D13 Tdark Non-IDG -0.10266 1.34 92
Rab GTPase-activating protein 1 RABGAP1 Tbio Enzyme -0.72004 3.69 184
TBC1 domain family member 26 TBC1D26 Tdark Non-IDG 0.00000 1.00 47
TBC1 domain family member 3G TBC1D3G Tdark Non-IDG 0.00000 5
TBC1 domain family member 8 TBC1D8 Tdark Non-IDG 0.21 0.48 69
TBC1 domain family member 9B TBC1D9B Tdark Non-IDG 0.66 0.43 29
TBC1 domain family member 2A TBC1D2 Tbio Non-IDG -1.28188 18.5 80
Ral GTPase-activating protein subunit alpha-1 RALGAPA1 Tbio Enzyme -1.56324 36.8 56