Development Level

Tbio 13 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 13 | 11,493
ependymoma 8 | 4,679
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Kidney cancer 6 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
medulloblastoma, large-cell 6 | 6,241
atypical teratoid / rhabdoid tumor 5 | 5,112
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
esophageal adenocarcinoma 4 | 737
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
subependymal giant cell astrocytoma 4 | 2,287
astrocytoma 3 | 1,146
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
Anemia 2 | 365
Anemia, Hemolytic 2 | 55
Anemia, hereditary spherocytic hemolytic 2 | 5
Atrophy of cerebellum 2 | 103
Autosomal recessive predisposition 2 | 1,442
Cerebellar degeneration 2 | 103
Congenital hemolytic anemia 2 | 32
Duchenne muscular dystrophy 2 | 601
Elliptocytosis, Hereditary 2 | 9
Hereditary elliptocytosis 2 | 22
Hereditary spherocytosis 2 | 16
Hyperreflexia 2 | 209
Infantile onset 2 | 238
Infratentorial atrophy 2 | 103
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Melanoma 2 | 711
Neuropathy 2 | 261
Osteoporosis 2 | 363
Polycystic ovary syndrome 2 | 360
Schizophrenia 2 | 1,160
Spherocytosis 2 | 5
Weight Gain 2 | 100
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Abnormal coordination 1 | 15
Amyloidosis 1 | 67
Ataxia, Appendicular 1 | 25
Ataxia, Spinocerebellar 1 | 16
Bulbar palsy 1 | 19
Bulbar weakness 1 | 19
COPD 1 | 118
Carcinoma, Renal Cell 1 | 124
Cerebellar Dysmetria 1 | 56
Chemical and Drug Induced Liver Injury 1 | 195
DOID:9917 1 | 31
Dacryoadenitis 1 | 10
Doyne honeycomb retinal dystrophy 1 | 9
Dysdiadochokinesis 1 | 25
Elliptocytosis found 1 | 7
Epileptic encephalopathy 1 | 26
Fractures, Bone 1 | 13
Gaucher disease type 1 1 | 180
Gestational diabetes 1 | 26
Hypercalcemia 1 | 59
Hypsarrhythmia 1 | 25
Increased bilirubin level (finding) 1 | 18
Lymphoid leukemia 1 | 160
Nephrotic Syndrome 1 | 78
Neurodegenerative Disorders 1 | 79
Nystagmus, End-Position 1 | 12
Osteomalacia 1 | 35
Peripheral Neuropathy 1 | 134
Postpartum depression 1 | 8
Pre-Eclampsia 1 | 68
Progressive microcephaly 1 | 32
Renal Cell Carcinoma 1 | 214
Rickets 1 | 49
Spastic Quadriplegia 1 | 42
Spinocerebellar Ataxias 1 | 34
Vesicoureteral reflux 1 | 32
West Syndrome 1 | 28
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 13 | 16,909
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Skin and soft tissues 13 | 17,230
Digestive Tract 12 | 17,369
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 13 | 12,091

GO Process

actin filament capping 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spectrin beta chain, non-erythrocytic 2 SPTBN2 Tbio Non-IDG -1.73436 53.8 237
Adseverin SCIN Tbio Non-IDG -1.90989 89.8 72
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Spectrin alpha chain, erythrocytic 1 SPTA1 Tbio Non-IDG -2.93650 850.7 86
Spectrin beta chain, erythrocytic SPTB Tbio Non-IDG -2.45982 275.1 59
Gelsolin GSN Tbio Non-IDG -3.11676 1340.4 481
Spectrin beta chain, non-erythrocytic 4 SPTBN4 Tbio Non-IDG -1.35996 22.3 58
Villin-1 VIL1 Tbio Non-IDG -2.20137 162.5 349
Dematin DMTN Tbio Non-IDG -1.73686 56.6 158
Villin-like protein VILL Tbio Non-IDG -1.29743 18.2 79