Development Level

Tbio 27 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
increased or absent threshold ... 3 | 101
absent pinna reflex 2 | 23
decreased circulating insulin ... 2 | 76
decreased spleen weight 2 | 10
improved glucose tolerance 2 | 79
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coping response 1 | 1
abnormal cranium morphology 1 | 36
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased vertical activity 1 | 24
limb grasping 1 | 41
short tibia 1 | 97
small testis 1 | 58
stereotypic behavior 1 | 3
thrombocytopenia 1 | 56
trunk curl 1 | 16

Disease

Carcinoma 25 | 11,493
glioblastoma 19 | 5,792
medulloblastoma, large-cell 19 | 6,241
ovarian cancer 18 | 8,520
osteosarcoma 17 | 7,950
psoriasis 14 | 6,694
ependymoma 13 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
lung cancer 13 | 4,740
Astrocytoma, Pilocytic 12 | 3,081
group 3 medulloblastoma 12 | 4,104
astrocytic glioma 11 | 2,597
oligodendroglioma 11 | 2,850
Cancer 10 | 2,499
atypical teratoid / rhabdoid tumor 10 | 5,112
interstitial cystitis 10 | 2,312
pancreatic cancer 10 | 2,398
Breast cancer 9 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
ulcerative colitis 9 | 1,819
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
invasive ductal carcinoma 7 | 2,951
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Duchenne muscular dystrophy 6 | 601
esophageal adenocarcinoma 6 | 737
lung adenocarcinoma 6 | 2,716
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Kidney cancer 5 | 2,613
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
colon cancer 5 | 1,478
malignant mesothelioma 5 | 3,232
Liver Cirrhosis, Experimental 4 | 769
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Animal Mammary Neoplasms 3 | 136
Atopic dermatitis 3 | 952
Becker muscular dystrophy 3 | 191
Down syndrome 3 | 499
Intellectual disability 3 | 1,016
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Nonsyndromic deafness 3 | 142
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
chronic lymphosyte leukemia 3 | 204
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
gastric cancer 3 | 459
group 4 medulloblastoma 3 | 1,855
mucosa-associated lymphoid tissue lymphoma 3 | 484
urothelial carcinoma 3 | 318
Arthritis, Rheumatoid 2 | 174
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Barrett's esophagus 2 | 182
Bipolar Disorder 2 | 666
Cataract 2 | 297
Degenerative polyarthritis 2 | 115
Difficulties with night vision 2 | 87
Dull intelligence 2 | 645
Electroretinogram abnormal 2 | 95
Hypertension 2 | 396
Lens Opacities 2 | 231
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Night Blindness 2 | 101
Osteoarthritis 2 | 184
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Retinitis Pigmentosa 2 | 226
Sensorineural Hearing Loss (disorder) 2 | 284
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
dentatorubral-pallidoluysian atrophy 2 | 21
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
primary Sjogren syndrome 2 | 735
sarcoidosis 2 | 370

Tissue

Blood and immune system 31 | 16,909
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Digestive Tract 30 | 17,369
Nervous System 30 | 16,725
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 7 | 4,145

GO Process

actin filament bundle assembly 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 BAIAP2L1 Tbio Non-IDG -1.09082 14.4 138
Myristoylated alanine-rich C-kinase substrate MARCKS Tbio Enzyme -2.67762 525.7 663
Alpha-actinin-4 ACTN4 Tbio Non-IDG -2.22522 178.2 300
Espin-like protein ESPNL Tdark Non-IDG 0.04 0.97 65
Unconventional myosin-Ib MYO1B Tbio Non-IDG -1.76878 60.8 85
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
PRKC apoptosis WT1 regulator protein PAWR Tbio Non-IDG -1.93678 105.8 292