Development Level

Tbio 31 | 10,625
Tchem 13 | 1,890
Tclin 2 | 602
Tdark 1 | 7,003

Collection

Kinase: IDG Consortium (Targets) 3 | 125
Kinase: IDG Consortium (Complete/Control) 2 | 37
GPCR: IDG Consortium (Complete/Control) 1 | 24

IMPC Phenotype

decreased lean body mass 4 | 195
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased kidney weight 2 | 7
impaired pupillary reflex 2 | 14
preweaning lethality, complete... 2 | 633
abnormal bone mineralization 1 | 55
abnormal coat-hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal digestive system phys... 1 | 1
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris pigmentation 1 | 3
abnormal pelvic girdle bone mo... 1 | 11
abnormal posture 1 | 5
abnormal response to new envir... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
absent startle reflex 1 | 15
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lymphocyte cell numb... 1 | 9
decreased mature B cell number 1 | 25
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
enlarged heart 1 | 111
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating iron lev... 1 | 25
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
mydriasis 1 | 9
narrow eye opening 1 | 15
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20

Disease

ovarian cancer 30 | 8,491
osteosarcoma 27 | 7,933
medulloblastoma, large-cell 23 | 6,234
glioblastoma 22 | 5,572
psoriasis 21 | 6,685
atypical teratoid / rhabdoid tumor 19 | 4,369
lung cancer 19 | 4,473
Cancer 18 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
lung carcinoma 16 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
malignant mesothelioma 14 | 3,163
pancreatic cancer 14 | 2,300
pediatric high grade glioma 14 | 2,712
subependymal giant cell astrocytoma 14 | 2,287
astrocytic glioma 13 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
invasive ductal carcinoma 13 | 2,950
non-small cell lung cancer 13 | 2,798
pilocytic astrocytoma 13 | 3,086
interstitial cystitis 12 | 2,299
oligodendroglioma 12 | 2,849
Breast cancer 11 | 3,098
diabetes mellitus 11 | 1,663
primitive neuroectodermal tumor 11 | 3,031
Carcinoma 10 | 2,147
lung adenocarcinoma 10 | 2,714
primary pancreatic ductal adenocarcinoma 10 | 1,271
tuberculosis 10 | 1,563
group 4 medulloblastoma 9 | 1,875
Pick disease 8 | 1,893
acute quadriplegic myopathy 8 | 1,157
ulcerative colitis 8 | 2,087
Rheumatoid Arthritis 7 | 1,170
breast carcinoma 7 | 1,614
cutaneous lupus erythematosus 7 | 1,056
ependymoma 7 | 2,514
juvenile dermatomyositis 7 | 1,189
mucosa-associated lymphoid tissue lymphoma 7 | 480
posterior fossa group B ependymoma 7 | 1,530
primary Sjogren syndrome 7 | 788
astrocytoma 6 | 1,493
gastric carcinoma 6 | 832
group 3 medulloblastoma 6 | 2,254
medulloblastoma 6 | 1,524
pituitary cancer 6 | 1,972
spina bifida 6 | 1,064
adrenocortical carcinoma 5 | 1,427
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,670
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
posterior fossa group A ependymoma 5 | 1,511
sonic hedgehog group medulloblastoma 5 | 1,482
Amyotrophic Lateral Sclerosis 4 | 432
Duchenne muscular dystrophy 4 | 602
Mammary Neoplasms 4 | 410
Prostatic Neoplasms 4 | 471
Renal Cell Carcinoma 4 | 199
acute myeloid leukemia 4 | 785
adult high grade glioma 4 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
pancreatic carcinoma 4 | 567
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Animal Mammary Neoplasms 3 | 135
Bipolar Disorder 3 | 266
Blastic phase chronic myeloid leukemia 3 | 58
Chronic Myelocytic Leukemia Accelerated Phase 3 | 59
Crohn's disease 3 | 304
Gastrointestinal stromal tumor 3 | 61
Heart disease 3 | 279
IGA Glomerulonephritis 3 | 454
Intellectual disability 3 | 573
Juvenile arthritis 3 | 124
Kidney disease 3 | 397
Mammary Neoplasms, Experimental 3 | 149
Multiple Sclerosis 3 | 498
Neoplasm Invasiveness 3 | 127
Nonsyndromic deafness 3 | 121
Obesity 3 | 616
Pancreatic Neuroendocrine Tumor 3 | 45
Polycystic Ovary Syndrome 3 | 334
Proteinuria 3 | 63
Schizophrenia 3 | 503
Waldenstrons macroglobulinemia 3 | 764
active Crohn's disease 3 | 918
atypical teratoid/rhabdoid tumor 3 | 1,095
chronic lymphosyte leukemia 3 | 232
fibroadenoma 3 | 557
gastric cancer 3 | 436
nasopharyngeal carcinoma 3 | 1,056
progressive supranuclear palsy 3 | 674
Alzheimer's disease 2 | 644
Becker muscular dystrophy 2 | 187
Down syndrome 2 | 548
aldosterone-producing adenoma 2 | 664
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 550
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 47 | 17,994
Cardiovascular System 47 | 17,957
Digestive Tract 47 | 18,472
Endocrine System 47 | 18,511
Liver and Pancreas 47 | 18,135
Nervous System 47 | 18,560
Urinary Tract 47 | 18,443
Female tissues 46 | 18,646
Male tissues 46 | 17,968
Respiratory system 46 | 17,483
Skin and soft tissues 46 | 18,114

Target Family

Non-IDG 23 | 11,969
Kinase 13 | 634
Enzyme 6 | 4,146
GPCR 3 | 408
Ion Channel 1 | 341
Transporter 1 | 473

GO Process

actin cytoskeleton reorganizat... 47 | 47
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Muskelin MKLN1 Tbio Non-IDG -1.02215 14.1 90
Tyrosine-protein kinase Fer FER Tchem Kinase -1.84299 53.1 358
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tdark Non-IDG -0.54525 4.54 37
FERM, RhoGEF and pleckstrin domain-containing protein 2 FARP2 Tbio Non-IDG -0.69662 6.73 83
Phosphatase and actin regulator 1 PHACTR1 Tbio Enzyme -1.75360 59.1 34
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.27458 228.6 993
Myosin-9 MYH9 Tbio Non-IDG -2.98804 996.7 305
Ras-related protein Rap-2a RAP2A Tbio Enzyme -2.06534 111.8 96
Serine/threonine-protein kinase MRCK alpha CDC42BPA Tchem Kinase -1.28162 21.4 151
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.52825 345.1 271