Development Level

Tbio 88 | 11,445
Tchem 17 | 1,598
Tdark 12 | 6,588
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 6 | 125
Kinase: IDG Consortium (Comple... 3 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal embryo size 6 | 220
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to t... 5 | 278
abnormal bone structure 4 | 187
abnormal behavior 3 | 298
abnormal cranium morphology 3 | 36
abnormal retina morphology 3 | 71
decreased bone mineral content 3 | 151
decreased mean corpuscular vol... 3 | 79
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
hyperactivity 3 | 148
increased circulating alkaline... 3 | 122
abnormal maxilla morphology 2 | 17
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
edema 2 | 59
enlarged spleen 2 | 41
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased mean corpuscular hem... 2 | 36
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal duodenum morphology 1 | 4
abnormal embryo turning 1 | 31
abnormal kidney morphology 1 | 65
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
enlarged uterus 1 | 11
fused cornea and lens 1 | 5
head bobbing 1 | 5
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased caudal vertebrae num... 1 | 7
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
male infertility 1 | 123
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 96 | 11,493
osteosarcoma 65 | 7,950
glioblastoma 56 | 5,792
ovarian cancer 56 | 8,520
atypical teratoid / rhabdoid tumor 55 | 5,112
medulloblastoma, large-cell 55 | 6,241
psoriasis 48 | 6,694
ependymoma 46 | 4,679
group 3 medulloblastoma 36 | 4,104
adult high grade glioma 33 | 3,801
lung cancer 32 | 4,740
Astrocytoma, Pilocytic 31 | 3,081
Breast cancer 31 | 3,578
primitive neuroectodermal tumor 30 | 3,035
invasive ductal carcinoma 29 | 2,951
subependymal giant cell astrocytoma 29 | 2,287
Kidney cancer 28 | 2,613
Cancer 27 | 2,499
lung carcinoma 27 | 2,843
pancreatic cancer 27 | 2,398
malignant mesothelioma 26 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
non-small cell lung cancer 24 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
oligodendroglioma 23 | 2,850
ulcerative colitis 21 | 1,819
lung adenocarcinoma 20 | 2,716
astrocytic glioma 19 | 2,597
group 4 medulloblastoma 19 | 1,855
breast carcinoma 16 | 1,638
cystic fibrosis 16 | 1,696
ductal carcinoma in situ 16 | 1,745
primary pancreatic ductal adenocarcinoma 16 | 1,109
Intellectual disability 15 | 1,016
Pick disease 15 | 1,894
Rheumatoid arthritis 15 | 1,191
astrocytoma 15 | 1,146
interstitial cystitis 14 | 2,312
adrenocortical carcinoma 13 | 1,428
spina bifida 13 | 1,074
tuberculosis 13 | 2,010
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
acute quadriplegic myopathy 12 | 1,158
colon cancer 12 | 1,478
juvenile dermatomyositis 12 | 1,187
pediatric high grade glioma 12 | 1,064
Schizophrenia 11 | 1,160
pituitary cancer 11 | 1,972
gastric carcinoma 10 | 807
Liver cancer 9 | 604
Multiple myeloma 9 | 1,332
mucosa-associated lymphoid tissue lymphoma 9 | 484
Attention deficit hyperactivity disorder 8 | 278
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Melanoma 8 | 711
Mental and motor retardation 8 | 608
Short stature 8 | 531
active Crohn's disease 8 | 922
diabetes mellitus 8 | 1,728
Autosomal recessive predisposition 7 | 1,442
Depressive disorder 7 | 409
Hypertension 7 | 396
Muscle hypotonia 7 | 571
Obesity 7 | 678
Waldenstrons macroglobulinemia 7 | 765
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Aarskog syndrome 6 | 12
Acquired flat foot 6 | 72
Breast Neoplasms 6 | 445
Fatigue 6 | 182
Flatfoot 6 | 73
Mammary Neoplasms 6 | 425
Orbital separation excessive 6 | 244
Short nose 6 | 132
Skin cancer 6 | 469
Small nose 6 | 132
active ulcerative colitis 6 | 764
atypical teratoid/rhabdoid tumor 6 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
esophageal adenocarcinoma 6 | 737
pancreatic carcinoma 6 | 562
Alzheimer's disease 5 | 658
Curvature of spine 5 | 282
Duchenne muscular dystrophy 5 | 601
Endometriosis 5 | 540
Epilepsy 5 | 792
Hypoplastic mandible condyle 5 | 275
Immune system cancer 5 | 140
Low-set, posteriorly rotated ears 5 | 110
aldosterone-producing adenoma 5 | 665
gastric cancer 5 | 459
nasopharyngeal carcinoma 5 | 1,058

Tissue

Endocrine System 119 | 18,159
Male tissues 118 | 17,142
Digestive Tract 117 | 17,369
Female tissues 117 | 17,400
Skin and soft tissues 117 | 17,230
Liver and Pancreas 116 | 16,750
Nervous System 116 | 16,725
Blood and immune system 115 | 16,909
Urinary Tract 115 | 16,678
Cardiovascular System 114 | 15,192
Respiratory system 114 | 16,393

Target Family

Non-IDG 78 | 12,091
Enzyme 23 | 4,145
Kinase 17 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
Transporter 1 | 473

GO Process

actin cytoskeleton organizatio... 122 | 122
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
GAS2-like protein 3 GAS2L3 Tbio Non-IDG -0.65733 5.79 78
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Xin actin-binding repeat-containing protein 2 XIRP2 Tbio Non-IDG -0.94115 9.06 17
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Rho guanine nucleotide exchange factor 17 ARHGEF17 Tbio Non-IDG -1.38408 25.0 61
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Xin actin-binding repeat-containing protein 1 XIRP1 Tbio Non-IDG -2.15574 137.9 66
Formin-like protein 3 FMNL3 Tbio Non-IDG -1.05785 13.4 42
Rho guanine nucleotide exchange factor 18 ARHGEF18 Tbio Non-IDG -0.76671 7.19 177