Development Level

Tbio 76 | 11,445
Tclin 5 | 613
Tdark 5 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
abnormal bone structure 2 | 187
abnormal kidney morphology 2 | 65
corneal opacity 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased startle reflex 2 | 75
hydrometra 2 | 53
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal eyelid morphology 1 | 7
abnormal head morphology 1 | 10
abnormal head size 1 | 6
abnormal heart shape 1 | 5
abnormal iris morphology 1 | 13
abnormal placement of pupils 1 | 6
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged seminal vesicle 1 | 10
fused cornea and lens 1 | 5
hydrops fetalis 1 | 1
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating amylase ... 1 | 25
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating insulin ... 1 | 3
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
irregularly shaped pupil 1 | 7
mammalian phenotype 1 | 17
microphthalmia 1 | 26
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
trunk curl 1 | 16

Disease

ovarian cancer 63 | 8,520
Carcinoma 51 | 11,493
osteosarcoma 38 | 7,950
lung cancer 37 | 4,740
psoriasis 37 | 6,694
glioblastoma 34 | 5,792
Multiple myeloma 32 | 1,332
Breast cancer 25 | 3,578
ependymoma 25 | 4,679
atypical teratoid / rhabdoid tumor 24 | 5,112
Cancer 21 | 2,499
medulloblastoma, large-cell 20 | 6,241
group 3 medulloblastoma 18 | 4,104
non-small cell lung cancer 18 | 2,890
HIV Infections 16 | 102
malignant mesothelioma 16 | 3,232
subependymal giant cell astrocytoma 16 | 2,287
Astrocytoma, Pilocytic 15 | 3,081
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
Waldenstrons macroglobulinemia 12 | 765
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
oligodendroglioma 12 | 2,850
dermatomyositis 11 | 966
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung adenocarcinoma 11 | 2,716
lung carcinoma 11 | 2,843
Kidney cancer 10 | 2,613
Pick disease 10 | 1,894
astrocytoma 10 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
tuberculosis 10 | 2,010
astrocytic glioma 9 | 2,597
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
Rheumatoid arthritis 8 | 1,191
acute myeloid leukemia 8 | 783
diabetes mellitus 8 | 1,728
ductal carcinoma in situ 8 | 1,745
non primary Sjogren syndrome sicca 8 | 891
pituitary cancer 8 | 1,972
acute quadriplegic myopathy 7 | 1,158
breast carcinoma 7 | 1,638
primary pancreatic ductal adenocarcinoma 7 | 1,109
Intellectual disability 6 | 1,016
Liver Cirrhosis, Experimental 6 | 769
cystic fibrosis 6 | 1,696
esophageal adenocarcinoma 6 | 737
pediatric high grade glioma 6 | 1,064
spina bifida 6 | 1,074
Cleft Palate 5 | 271
Cognitive delay 5 | 608
Cryptorchidism 5 | 296
Frontal bossing 5 | 157
Global developmental delay 5 | 608
Hypoplastic mandible condyle 5 | 275
Long philtrum 5 | 137
Mandibular hypoplasia 5 | 275
Mantle cell lymphoma 5 | 23
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Orbital separation excessive 5 | 244
Robinow syndrome 5 | 11
Schizophrenia 5 | 1,160
active Crohn's disease 5 | 922
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
group 4 medulloblastoma 5 | 1,855
primary Sjogren syndrome 5 | 735
ulcerative colitis 5 | 1,819
Autosomal recessive predisposition 4 | 1,442
Broad flat nasal bridge 4 | 236
Congenital hypoplasia of penis 4 | 176
Curvature of digit 4 | 57
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Epilepsy 4 | 792
Gingival Hyperplasia 4 | 34
Gingival Hypertrophy 4 | 34
Gingival Overgrowth 4 | 36
Hernia, Inguinal 4 | 89
Increased head circumference 4 | 147
Low intelligence 4 | 645
Macroglossia 4 | 65
Mental deficiency 4 | 645
Nasal bridge wide 4 | 236
Neurodegenerative disease 4 | 414
Pectus excavatum 4 | 100
Poor school performance 4 | 645
Radially deviated fingers 4 | 38
Umbilical hernia 4 | 93
Vascular disease 4 | 319
Wide anterior fontanel 4 | 44
adrenocortical carcinoma 4 | 1,428
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720

Tissue

Endocrine System 90 | 18,159
Blood and immune system 89 | 16,909
Digestive Tract 89 | 17,369
Female tissues 89 | 17,400
Nervous System 89 | 16,725
Urinary Tract 89 | 16,678
Male tissues 88 | 17,142
Respiratory system 88 | 16,393
Liver and Pancreas 87 | 16,750
Skin and soft tissues 87 | 17,230
Cardiovascular System 86 | 15,192

Target Family

Enzyme 46 | 4,145
Non-IDG 33 | 12,091
GPCR 10 | 408
Kinase 1 | 634

GO Process

Wnt signaling pathway, planar ... 90 | 90
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Cadherin EGF LAG seven-pass G-type receptor 3 CELSR3 Tbio GPCR -1.38072 25.3 190
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43