Development Level

Tbio 27 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal heart morphology 5 | 162
enlarged heart 5 | 210
abnormal behavior 3 | 298
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
decreased body weight 2 | 161
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
increased monocyte cell number 2 | 63
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
hydrometra 1 | 53
hydrops fetalis 1 | 1
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cellular hemoglobin ... 1 | 1
increased circulating creatini... 1 | 38
increased circulating insulin ... 1 | 3
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
macrophthalmia 1 | 2
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74

Disease

Carcinoma 31 | 11,493
ovarian cancer 23 | 8,520
osteosarcoma 22 | 7,950
atypical teratoid / rhabdoid tumor 21 | 5,112
ependymoma 21 | 4,679
psoriasis 20 | 6,694
medulloblastoma, large-cell 19 | 6,241
glioblastoma 18 | 5,792
lung cancer 15 | 4,740
primitive neuroectodermal tumor 15 | 3,035
Astrocytoma, Pilocytic 14 | 3,081
Pick disease 14 | 1,894
Breast cancer 13 | 3,578
astrocytic glioma 13 | 2,597
group 4 medulloblastoma 13 | 1,855
malignant mesothelioma 12 | 3,232
oligodendroglioma 12 | 2,850
Kidney cancer 10 | 2,613
adult high grade glioma 10 | 3,801
Cancer 9 | 2,499
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
subependymal giant cell astrocytoma 9 | 2,287
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung carcinoma 8 | 2,843
pancreatic cancer 8 | 2,398
Autosomal recessive predisposition 7 | 1,442
Intellectual disability 7 | 1,016
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
tuberculosis 7 | 2,010
Congenital hypoplasia of penis 6 | 176
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
colon cancer 6 | 1,478
juvenile dermatomyositis 6 | 1,187
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Abnormality of retinal pigmentation 5 | 111
Anteverted nostril 5 | 191
Broad flat nasal bridge 5 | 236
Colonic Neoplasms 5 | 142
Nasal bridge wide 5 | 236
Obesity 5 | 678
Retinal pigment epithelial abnormality 5 | 111
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Blind Vision 4 | 111
Blindness, Legal 4 | 110
Cognitive delay 4 | 608
Conductive hearing loss 4 | 123
Electroretinogram abnormal 4 | 95
Global developmental delay 4 | 608
Keratoconus 4 | 113
Liver cancer 4 | 604
Long philtrum 4 | 137
Mental and motor retardation 4 | 608
Nystagmus 4 | 317
Orbital separation excessive 4 | 244
Photodysphoria 4 | 121
Photophobia 4 | 121
Sensorineural Hearing Loss (disorder) 4 | 284
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
pediatric high grade glioma 4 | 1,064
Atopic dermatitis 3 | 952
Atrial Fibrillation 3 | 124
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Epilepsy 3 | 792
Glaucoma 3 | 239
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Neurodevelopmental Disorders 3 | 70
Prostatic Neoplasms 3 | 495
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
progressive supranuclear palsy 3 | 676

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Cardiovascular System 35 | 15,192
Urinary Tract 35 | 16,678

Target Family

Non-IDG 16 | 12,091
Enzyme 9 | 4,145
GPCR 5 | 408
Kinase 4 | 634
Transcription Factor 3 | 1,400

GO Process

Wnt signaling pathway, calcium... 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.60752 391.4 125
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 PLCB3 Tbio Enzyme -1.88444 66.2 265
Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Tbio Non-IDG -2.24331 158.7 195
Frizzled-6 FZD6 Tbio GPCR -1.63747 44.5 260