Development Level

Tbio 138 | 11,651
Tchem 29 | 1,388
Tdark 5 | 6,593
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 5 | 125
RFA-RM-18-021 5 | 328
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 979
decreased vertical activity 7 | 208
abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
enlarged heart 5 | 210
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
increased startle reflex 4 | 112
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
abnormal facial morphology 3 | 17
abnormal head shape 3 | 10
anophthalmia 3 | 33
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
decreased prepulse inhibition 3 | 82
improved glucose tolerance 3 | 79
increased total body fat amoun... 3 | 134
microphthalmia 3 | 26
small testis 3 | 58
abnormal bone mineralization 2 | 38
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal kidney morphology 2 | 65
abnormal limb morphology 2 | 13
abnormal optic disc morphology 2 | 10
abnormal testis morphology 2 | 43
cleft palate 2 | 8
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
decreased total retina thickne... 2 | 17
edema 2 | 59
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
thrombocytosis 2 | 27
abnormal body wall morphology 1 | 9
abnormal brain morphology 1 | 13
abnormal coat- hair morphology 1 | 19
abnormal eyelid morphology 1 | 7
abnormal head morphology 1 | 10
abnormal head size 1 | 6
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
corneal opacity 1 | 32
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
facial cleft 1 | 3
female infertility 1 | 60
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased T cell number 1 | 6
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
prenatal lethality 1 | 28
prolonged PQ interval 1 | 5
small adrenal glands 1 | 16
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 122 | 11,493
ovarian cancer 94 | 8,520
osteosarcoma 85 | 7,950
medulloblastoma, large-cell 73 | 6,241
psoriasis 66 | 6,694
glioblastoma 64 | 5,792
atypical teratoid / rhabdoid tumor 57 | 5,112
Cancer 55 | 2,499
lung cancer 51 | 4,740
ependymoma 46 | 4,679
Breast cancer 45 | 3,578
adult high grade glioma 42 | 3,801
group 3 medulloblastoma 42 | 4,104
malignant mesothelioma 38 | 3,232
Kidney cancer 35 | 2,613
primitive neuroectodermal tumor 35 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
invasive ductal carcinoma 34 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
non-small cell lung cancer 33 | 2,890
Astrocytoma, Pilocytic 32 | 3,081
oligodendroglioma 32 | 2,850
astrocytic glioma 31 | 2,597
breast carcinoma 31 | 1,638
interstitial cystitis 30 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
lung adenocarcinoma 29 | 2,716
lung carcinoma 27 | 2,843
subependymal giant cell astrocytoma 25 | 2,287
pancreatic cancer 24 | 2,398
cystic fibrosis 23 | 1,696
ulcerative colitis 23 | 1,819
Schizophrenia 20 | 1,160
group 4 medulloblastoma 20 | 1,855
adrenocortical carcinoma 19 | 1,428
medulloblastoma 18 | 720
pituitary cancer 18 | 1,972
ductal carcinoma in situ 17 | 1,745
primary pancreatic ductal adenocarcinoma 17 | 1,109
juvenile dermatomyositis 16 | 1,187
Pick disease 15 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Osteoporosis 14 | 363
astrocytoma 14 | 1,146
dermatomyositis 14 | 966
tuberculosis 14 | 2,010
colon cancer 13 | 1,478
Breast Neoplasms 12 | 445
Intellectual disability 12 | 1,016
Obesity 12 | 678
Rheumatoid arthritis 12 | 1,191
acute myeloid leukemia 12 | 783
acute quadriplegic myopathy 12 | 1,158
cutaneous lupus erythematosus 12 | 1,057
diabetes mellitus 12 | 1,728
Alzheimer's disease 11 | 658
Autosomal recessive predisposition 11 | 1,442
Bipolar Disorder 11 | 666
Mammary Neoplasms 11 | 425
Multiple myeloma 11 | 1,332
non primary Sjogren syndrome sicca 11 | 891
spina bifida 11 | 1,074
Crohn's disease 9 | 321
Parkinson's disease 9 | 392
Stomach Neoplasms 9 | 300
esophageal adenocarcinoma 9 | 737
Colorectal Neoplasms 8 | 243
Liver cancer 8 | 604
Short stature 8 | 531
Waldenstrons macroglobulinemia 8 | 765
fibroadenoma 8 | 559
Atopic dermatitis 7 | 952
Cleft Palate 7 | 271
Cognitive delay 7 | 608
Duchenne muscular dystrophy 7 | 601
Endometrial cancer 7 | 311
Global developmental delay 7 | 608
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Mental and motor retardation 7 | 608
Micrognathism 7 | 275
Renal Cell Carcinoma 7 | 214
progressive supranuclear palsy 7 | 676
tuberculosis and treatment for 6 months 7 | 409
Carcinoma, Hepatocellular 6 | 228
Dull intelligence 6 | 645
Kidney disease 6 | 430
Liver carcinoma 6 | 240
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Vascular disease 6 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric carcinoma 6 | 807
hepatocellular carcinoma 6 | 547
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
primary Sjogren syndrome 6 | 735
sonic hedgehog group medulloblastoma 6 | 467

Tissue

Endocrine System 172 | 18,159
Digestive Tract 171 | 17,369
Female tissues 171 | 17,400
Nervous System 170 | 16,725
Skin and soft tissues 169 | 17,230
Male tissues 168 | 17,142
Blood and immune system 167 | 16,909
Liver and Pancreas 166 | 16,750
Urinary Tract 165 | 16,678
Respiratory system 161 | 16,393
Cardiovascular System 155 | 15,192

Target Family

Non-IDG 107 | 12,091
Enzyme 27 | 4,145
Kinase 21 | 634
Transcription Factor 13 | 1,400
GPCR 4 | 408
Epigenetic 2 | 242
Transporter 1 | 473

GO Process

Wnt signaling pathway 175 | 175
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
Spindlin-1 SPIN1 Tbio Non-IDG -2.02987 109.3 128
Protein APCDD1 APCDD1 Tbio Non-IDG -0.89880 10.7 137
Wnt inhibitory factor 1 WIF1 Tbio Non-IDG -2.11284 143.2 350
F-box/WD repeat-containing protein 11 FBXW11 Tbio Non-IDG -0.75887 5.88 183
Vacuolar protein sorting-associated protein 35 VPS35 Tbio Non-IDG -2.02621 104.1 124
5'-AMP-activated protein kinase catalytic subunit alpha-2 PRKAA2 Tchem Kinase -1.42705 21.1 603
RNA polymerase-associated protein LEO1 LEO1 Tbio Enzyme -2.07251 114.4 293
Pygopus homolog 1 PYGO1 Tdark Epigenetic -0.48368 2.66 135
Frizzled-4 FZD4 Tbio GPCR -2.05508 106.8 313