Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal vocalization 1 | 21
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
increased body length 1 | 32
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
Cockayne syndrome 5 | 60
Hypogonadism 5 | 173
Melanoma 5 | 711
Xeroderma pigmentosum 5 | 43
osteosarcoma 5 | 7,950
Autosomal recessive predisposition 4 | 1,442
Basal cell carcinoma 4 | 54
Cataract 4 | 297
Cryptorchidism 4 | 296
Dry skin 4 | 75
Electroencephalogram abnormal 4 | 101
Freckles 4 | 33
Lens Opacities 4 | 231
Photodysphoria 4 | 121
Photophobia 4 | 121
Photosensitivity of skin 4 | 51
Sensorineural Hearing Loss (disorder) 4 | 284
Strabismus 4 | 270
Xerosis 4 | 75
lung cancer 4 | 4,740
Arthralgia 3 | 90
Atrophic condition of skin 3 | 25
Conjunctival telangiectasis 3 | 14
Conjunctivitis 3 | 53
Conjunctivitis, recurrent 3 | 37
Defective DNA repair after ultraviolet radiation damage 3 | 7
Dental abnormalities 3 | 60
Developmental regression 3 | 95
Ectropion 3 | 38
Entropion 3 | 22
Erythema 3 | 58
Failure to gain weight 3 | 365
Fatigue 3 | 182
Fever 3 | 138
Flushing 3 | 60
Hyperkeratosis 3 | 50
Hyperpigmented macules 3 | 42
Impaired cognition 3 | 96
Keratitis 3 | 62
Loss of developmental milestones 3 | 95
Mental deterioration in childhood 3 | 95
Mental impairment 3 | 95
Neoplasm Metastasis 3 | 168
Neurodevelopmental regression 3 | 95
Optic Atrophy 3 | 242
Papilloma 3 | 44
Pediatric failure to thrive 3 | 365
Poikiloderma 3 | 14
Progressive mental retardation 3 | 37
Psychomotor regression 3 | 95
Psychomotor regression beginning in infancy 3 | 95
Psychomotor regression in infants 3 | 95
Psychomotor regression, progressive 3 | 95
Spider Veins 3 | 17
Telangiectasia of the skin 3 | 39
Telangiectasis 3 | 36
Thin skin 3 | 47
Tooth Abnormalities 3 | 69
group 3 medulloblastoma 3 | 4,104
hypopigmented skin patch 3 | 59
malignant mesothelioma 3 | 3,232
Adenocarcinoma of lung 2 | 142
Adenocarcinoma of lung (disorder) 2 | 60
Basal cell nevi 2 | 23
Blepharophimosis 2 | 70
Breast cancer 2 | 3,578
Carcinoma, Basal Cell 2 | 28
Carcinoma, Non-Small-Cell Lung 2 | 107
Chromosome Aberrations 2 | 16
Disease Progression 2 | 136
Dull intelligence 2 | 645
Epilepsy 2 | 792
Intellectual disability 2 | 1,016
Liver neoplasms 2 | 130
Low Vision 2 | 174
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Nystagmus 2 | 317
Obesity 2 | 678
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Seizures 2 | 596
Short neck 2 | 140
Short philtrum 2 | 53
Short stature 2 | 531
Small head 2 | 374
Squamous cell carcinoma of skin 2 | 11
Stomach Neoplasms 2 | 300
Visual Impairment 2 | 174
inflammatory breast cancer 2 | 286
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

UV-damage excision repair 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Actin-related protein 5 ACTR5 Tbio Non-IDG 0.08 0.95 92
Histone H2A type 3 HIST3H2A Tbio Non-IDG 0.00000 35
DNA damage-binding protein 1 DDB1 Tbio Non-IDG -2.34719 202.5 353
Cullin-4B CUL4B Tbio Non-IDG -1.68710 54.9 251
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.21142 154.0 208
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.87504 739.6 379
DNA damage-binding protein 2 DDB2 Tbio Non-IDG -2.07539 123.8 172
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.50639 3413.7 733