Development Level

Tchem 2 | 1,388
Tbio 1 | 11,651

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased bone mineral content 1 | 151
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Cancer 3 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Adenocarcinoma 2 | 122
Autoimmune lymphoproliferative syndrome 2 | 11
Autosomal recessive predisposition 2 | 1,442
Carcinoma 2 | 11,493
Esophageal Neoplasms 2 | 69
glioblastoma 2 | 5,792
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Addison's disease 1 | 31
Age related macular degeneration 1 | 72
Alopecia 1 | 115
Anemia 1 | 365
Ankylosing spondylitis 1 | 140
Anorexia 1 | 43
Arthropathy 1 | 43
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Breast Neoplasms 1 | 445
Carcinoma, Hepatocellular 1 | 228
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, squamous cell of head and neck 1 | 31
Cerebral Hemorrhage 1 | 42
Cerebral atrophy 1 | 178
Chronic diarrhea 1 | 29
Colonic Neoplasms 1 | 142
Colorectal Neoplasms 1 | 243
Craniofacial Abnormalities 1 | 151
Decreased T cell activation 1 | 4
Decreased liver function 1 | 24
Defective B cell activation 1 | 1
Degenerative brain disorder 1 | 100
Dermatitis, Allergic Contact 1 | 67
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Dilated cardiomyopathy 1 | 56
Drug Hypersensitivity 1 | 34
Drug allergy 1 | 36
Eczema 1 | 45
Edema 1 | 81
Encephalopathies 1 | 43
Epilepsy 1 | 792
Failure to gain weight 1 | 365
Fatigue 1 | 182
Felty's syndrome 1 | 7
Hypersensitivity reaction type II disease 1 | 253
Increased hepatocellular carcinoma risk 1 | 27
Increased incidence of hepatocellular carcinoma 1 | 27
Liver Dysfunction 1 | 99
Liver carcinoma 1 | 240
Liver disease 1 | 237
Liver dysfunction, mild 1 | 24
Lung Neoplasms 1 | 232
Lymphadenopathy 1 | 62
Macular degeneration 1 | 65
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Micronodular cirrhosis 1 | 12
Mixed connective tissue disease 1 | 16
Multiple Sclerosis 1 | 540
Mumps 1 | 10
Myocardial Reperfusion Injury 1 | 37
Nausea 1 | 20
Neoplasm Metastasis 1 | 168
Neoplasms 1 | 63
Neurodegenerative disease 1 | 414
Neutropenia 1 | 72
Palindromic rheumatism 1 | 4
Papillomavirus Infections 1 | 3
Pediatric failure to thrive 1 | 365
Pemphigus 1 | 23
Peripheral Nervous System Diseases 1 | 52
Peripheral Neuropathy 1 | 134
Pneumonia 1 | 174
Polymyalgia rheumatica 1 | 10
Reactive airway disease 1 | 21
Recurrent infections 1 | 48
Recurrent sinopulmonary infections 1 | 6
Reperfusion Injury 1 | 86
Seizures 1 | 596
Sensorineural Hearing Loss (disorder) 1 | 284
Skin Neoplasms 1 | 69
Somatic mutation 1 | 61
Squamous cell carcinoma of the head and neck 1 | 29
Status Epilepticus 1 | 98
Stomach Neoplasms 1 | 300
Stomach cancer 1 | 30
Subacute progressive viral hepatitis 1 | 9
Supratentorial atrophy 1 | 94
Thrombocytopenia 1 | 197
Toxic encephalopathy 1 | 141
Type 2 diabetes mellitus 1 | 272
Uterine Cervical Neoplasm 1 | 25
Uterine Cervical Neoplasms 1 | 26
Uveitis 1 | 103
Vasculitis 1 | 80
Ventricular Septal Defects 1 | 119
esophageal cancer 1 | 22
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Enzyme 1 | 4,145

GO Process

TRAIL-activated apoptotic sign... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Tumor necrosis factor receptor superfamily member 10A TNFRSF10A Tchem Non-IDG -3.41373 2664.2 812
FAS-associated death domain protein FADD Tbio Non-IDG -2.70083 469.8 708