Development Level

Tbio 12 | 11,651
Tchem 2 | 1,388
Tclin 1 | 612

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating LDL chol... 1 | 13
increased mean corpuscular hem... 1 | 96
preweaning lethality, complete... 1 | 979

Disease

Cancer 10 | 2,499
Carcinoma 10 | 11,493
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Kidney cancer 6 | 2,613
medulloblastoma, large-cell 6 | 6,241
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
group 4 medulloblastoma 5 | 1,855
primitive neuroectodermal tumor 5 | 3,035
Alzheimer's disease 4 | 658
Intellectual disability 4 | 1,016
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Birt-Hogg-Dube syndrome 3 | 11
Breast cancer 3 | 3,578
Epilepsy 3 | 792
Inflammation 3 | 120
Lymphangioleiomyomatosis 3 | 16
Major Depressive Disorder 3 | 301
Muscular atrophy 3 | 71
Obesity 3 | 678
Renal Cell Carcinoma 3 | 214
Schizophrenia 3 | 1,160
Vascular disease 3 | 319
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
oligodendroglioma 3 | 2,850
progressive supranuclear palsy 3 | 676
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Asthma 2 | 385
Autistic Disorder 2 | 364
Breast Neoplasms 2 | 445
Carcinoma of colon 2 | 32
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Renal Cell 2 | 124
Colorectal Neoplasms 2 | 243
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Globe disease 2 | 67
Hyperglycemia 2 | 137
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypertrophy, Left Ventricular 2 | 24
Kidney angiomyolipoma 2 | 8
Kidney disease 2 | 430
Left Ventricular Hypertrophy 2 | 47
Liver carcinoma 2 | 240
Lymphoma, Mantle-Cell 2 | 11
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 2 | 12
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Mood Disorders 2 | 184
Neurofibromatosis 2 | 40
Open mouth 2 | 45
Ovarian Neoplasms 2 | 102
Oxyphilic adenoma 2 | 22
Pain 2 | 103
Parkinson's disease 2 | 392
Pneumothorax 2 | 23
Precancerous Conditions 2 | 80
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Toxic encephalopathy 2 | 141
Unipolar Depression 2 | 250
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
ovarian neoplasm 2 | 99
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Anxiety disorder 1 | 23
Autosomal dominant polycystic kidney disease 1 | 31
Cafe au lait spots, multiple 1 | 17
Compression of spinal cord 1 | 10
Congenital bronchogenic cyst 1 | 3
Ebstein anomaly 1 | 16
Fissured tongue 1 | 25
Marfanoid body habitus 1 | 11
Neurotoxicity Syndromes 1 | 26
Papule 1 | 43
Renal clear cell carcinoma 1 | 6
Spinal canal stenosis 1 | 12
Tuberous sclerosis 1 | 19

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Nervous System 14 | 16,725

Target Family

Non-IDG 10 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

TOR signaling 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 4E-binding protein 1 EIF4EBP1 Tbio Non-IDG -2.83637 578.9 1455
Trans-acting T-cell-specific transcription factor GATA-3 GATA3 Tbio Transcription Factor -3.20678 1568.2 636
Folliculin FLCN Tbio Non-IDG -2.60609 412.5 235
40S ribosomal protein S6 RPS6 Tbio Non-IDG -2.76789 501.6 920
GTPase RhebL1 RHEBL1 Tbio Enzyme -0.70141 4.79 102
Eukaryotic translation initiation factor 4E-binding protein 2 EIF4EBP2 Tbio Non-IDG -1.55776 33.4 189
Girdin CCDC88A Tbio Non-IDG -1.86485 83.3 197
Rapamycin-insensitive companion of mTOR RICTOR Tbio Non-IDG -2.79454 597.0 440
Ribosomal protein S6 kinase beta-1 RPS6KB1 Tchem Kinase -3.18361 0.00000 1818
Folliculin-interacting protein 1 FNIP1 Tbio Non-IDG -0.92010 6.73 74