Development Level

Tbio 18 | 11,445
Tchem 8 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal behavior 2 | 298
decreased body length 2 | 101
decreased lean body mass 2 | 135
increased hemoglobin content 2 | 45
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
absent seminal vesicle 1 | 4
decreased IgG1 level 1 | 8
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lumbar vertebrae num... 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged liver 1 | 2
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small seminal vesicle 1 | 10
small uterus 1 | 3
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 23 | 11,493
osteosarcoma 22 | 7,950
psoriasis 19 | 6,694
Cancer 17 | 2,499
ovarian cancer 15 | 8,520
cutaneous lupus erythematosus 14 | 1,057
glioblastoma 14 | 5,792
interstitial cystitis 12 | 2,312
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
invasive ductal carcinoma 11 | 2,951
ulcerative colitis 11 | 1,819
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
adult high grade glioma 9 | 3,801
lung carcinoma 9 | 2,843
primary Sjogren syndrome 9 | 735
subependymal giant cell astrocytoma 9 | 2,287
Autosomal recessive predisposition 8 | 1,442
Rheumatoid arthritis 8 | 1,191
atypical teratoid / rhabdoid tumor 8 | 5,112
breast carcinoma 8 | 1,638
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
malignant mesothelioma 8 | 3,232
tuberculosis 8 | 2,010
Breast cancer 7 | 3,578
Diarrhea 7 | 253
Kidney cancer 7 | 2,613
Schizophrenia 7 | 1,160
Severe combined immunodeficiency 7 | 51
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Astrocytoma, Pilocytic 6 | 3,081
Failure to gain weight 6 | 365
Hypersensitivity reaction type II disease 6 | 253
Pediatric failure to thrive 6 | 365
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
primitive neuroectodermal tumor 6 | 3,035
sarcoidosis 6 | 370
Breast Neoplasms 5 | 445
Hepatomegaly 5 | 285
Immunologic Deficiency Syndromes 5 | 113
Liver Cirrhosis, Experimental 5 | 769
Lymphopenia 5 | 67
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Prostatic Neoplasms 5 | 495
Splenomegaly 5 | 190
Vascular disease 5 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
Arthritis 4 | 290
Arthritis, Rheumatoid 4 | 174
Atopic dermatitis 4 | 952
Chronic Lymphocytic Leukemia 4 | 262
Fever 4 | 138
Heart disease 4 | 306
Kidney disease 4 | 430
Lymphadenopathy 4 | 62
Multiple Sclerosis 4 | 540
Recurrent respiratory infections 4 | 141
Type 1 diabetes mellitus 4 | 109
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acquired immunodeficiency syndrome 3 | 197
Alopecia 3 | 115
Anemia 3 | 365
Asthma 3 | 385
Autistic Disorder 3 | 364
Autoimmune Diseases 3 | 67
Crohn's disease 3 | 321
Depressive disorder 3 | 409
Eosinophilia 3 | 28
Hypereosinophilic syndrome 3 | 71
Inflammation 3 | 120
Lung disease 3 | 142
Major Depressive Disorder 3 | 301
Nonorganic psychosis 3 | 84
Osteoporosis 3 | 363
Pneumonia 3 | 174
Primary physiologic amenorrhea 3 | 55
Pruritus 3 | 58
Psychotic Disorders 3 | 151
Small testicle 3 | 75
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
fibroadenoma 3 | 559
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Skin and soft tissues 31 | 17,230
Cardiovascular System 30 | 15,192
Endocrine System 30 | 18,159
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Urinary Tract 30 | 16,678

Target Family

Non-IDG 12 | 12,091
Transcription Factor 7 | 1,400
Enzyme 6 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

T cell differentiation 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
POZ-, AT hook-, and zinc finger-containing protein 1 PATZ1 Tbio Transcription Factor -1.98463 95.1 106
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
Transcription factor SOX-4 SOX4 Tbio Transcription Factor -2.22104 164.2 211
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe LFNG Tbio Enzyme -1.50535 29.8 220
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518