Development Level

Tbio 49 | 11,445
Tchem 18 | 1,598
Tclin 16 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased vertical activity 2 | 208
increased blood urea nitrogen ... 2 | 48
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating serum al... 1 | 82
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Cancer 39 | 2,499
Rheumatoid arthritis 37 | 1,191
ovarian cancer 35 | 8,520
osteosarcoma 34 | 7,950
lung carcinoma 33 | 2,843
psoriasis 33 | 6,694
Carcinoma 32 | 11,493
lung cancer 30 | 4,740
interstitial cystitis 29 | 2,312
diabetes mellitus 26 | 1,728
glioblastoma 25 | 5,792
invasive ductal carcinoma 23 | 2,951
medulloblastoma, large-cell 22 | 6,241
sarcoidosis 21 | 370
tuberculosis 20 | 2,010
Hypersensitivity reaction type II disease 19 | 253
Systemic lupus erythematosus 19 | 194
adult high grade glioma 18 | 3,801
breast carcinoma 18 | 1,638
non-small cell lung cancer 18 | 2,890
Breast cancer 17 | 3,578
Multiple Sclerosis 17 | 540
Narcolepsy 17 | 72
cutaneous lupus erythematosus 17 | 1,057
Astrocytoma, Pilocytic 16 | 3,081
Berylliosis 16 | 28
Multiple Sclerosis, Susceptibility to 15 | 15
cystic fibrosis 15 | 1,696
primary Sjogren syndrome 15 | 735
subependymal giant cell astrocytoma 15 | 2,287
ulcerative colitis 15 | 1,819
Diffuse cutaneous systemic sclerosis 14 | 17
Narcolepsy-cataplexy 14 | 21
Schizophrenia 14 | 1,160
follicular lymphoma 14 | 20
limited scleroderma 14 | 19
malignant mesothelioma 14 | 3,232
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
ependymoma 13 | 4,679
pancreatic cancer 13 | 2,398
Autosomal recessive predisposition 12 | 1,442
Celiac disease 12 | 116
atypical teratoid / rhabdoid tumor 12 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
juvenile dermatomyositis 12 | 1,187
group 3 medulloblastoma 11 | 4,104
group 4 medulloblastoma 11 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
Arthritis, Rheumatoid 10 | 174
Asthma 10 | 385
Autoimmune Diseases 10 | 67
Hepatitis B 10 | 108
Immunologic Deficiency Syndromes 10 | 113
Kidney cancer 10 | 2,613
Juvenile rheumatoid arthritis 9 | 111
Proteinuria 9 | 144
ductal carcinoma in situ 9 | 1,745
Hypersensitivity 8 | 63
Waldenstrons macroglobulinemia 8 | 765
active Crohn's disease 8 | 922
astrocytoma 8 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primitive neuroectodermal tumor 8 | 3,035
Atopic dermatitis 7 | 952
Kidney disease 7 | 430
Liver Cirrhosis, Experimental 7 | 769
Liver disease 7 | 237
Melanoma 7 | 711
Pick disease 7 | 1,894
Recurrent respiratory infections 7 | 141
Renal Cell Carcinoma 7 | 214
Splenomegaly 7 | 190
Type 1 diabetes mellitus 7 | 109
Vasculitis 7 | 80
astrocytic glioma 7 | 2,597
dermatomyositis 7 | 966
Adult T-Cell Lymphoma/Leukemia 6 | 30
Arthritis 6 | 290
Breast Neoplasms 6 | 445
Crohn's disease 6 | 321
Diarrhea 6 | 253
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Hepatomegaly 6 | 285
Infantile onset 6 | 238
Intellectual disability 6 | 1,016
Leukemia-Lymphoma, Adult T-Cell 6 | 30
Mammary Neoplasms 6 | 425
Multiple myeloma 6 | 1,332
active ulcerative colitis 6 | 764
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
pancreatic carcinoma 6 | 562
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,109

Tissue

Blood and immune system 66 | 16,909
Liver and Pancreas 66 | 16,750
Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Respiratory system 65 | 16,393
Skin and soft tissues 65 | 17,230
Urinary Tract 65 | 16,678
Male tissues 64 | 17,142
Nervous System 62 | 16,725
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 68 | 12,091
Kinase 15 | 634
Enzyme 6 | 4,145

GO Process

T cell costimulation 89 | 89
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
T-cell receptor beta chain V region CTL-L17 TCRB Tdark Non-IDG 0.00000 0
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.53824 32.8 425
Signal transducer CD24 CD24 Tbio Non-IDG 0.00000 0
HLA class II histocompatibility antigen, DRB1-9 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0
HERV-H LTR-associating protein 2 HHLA2 Tbio Non-IDG -0.92991 7.39 131
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 489
Ephrin-B1 EFNB1 Tbio Non-IDG -2.26015 197.6 359
T-cell receptor beta-1 chain C region TRBC1 Tbio Non-IDG 0.00000 0