Development Level

Tbio 43 | 10,625
Tchem 13 | 1,890
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal seminal vesicle morph... 1 | 47
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
decreased B cell number 1 | 30
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating creatini... 1 | 31
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased respiratory quotient 1 | 12
enlarged heart 1 | 111
enlarged kidney 1 | 7
hydrometra 1 | 13
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased blood uric acid leve... 1 | 5
increased circulating chloride... 1 | 43
increased granulocyte number 1 | 8
increased heart weight 1 | 37
increased kidney weight 1 | 4
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
preweaning lethality, incomple... 1 | 260
prolonged PR interval 1 | 4

Disease

ovarian cancer 31 | 8,484
psoriasis 30 | 6,685
osteosarcoma 24 | 7,933
glioblastoma 23 | 5,572
lung cancer 21 | 4,466
Cancer 19 | 2,346
medulloblastoma, large-cell 19 | 6,234
atypical teratoid / rhabdoid tumor 18 | 4,369
Breast cancer 15 | 3,094
malignant mesothelioma 14 | 3,162
interstitial cystitis 13 | 2,299
pediatric high grade glioma 13 | 2,712
pilocytic astrocytoma 13 | 3,086
cystic fibrosis 12 | 1,665
invasive ductal carcinoma 12 | 2,950
oligodendroglioma 12 | 2,849
breast carcinoma 11 | 1,614
lung adenocarcinoma 11 | 2,713
lung carcinoma 11 | 2,844
non-small cell lung cancer 11 | 2,798
pancreatic cancer 11 | 2,300
ductal carcinoma in situ 10 | 1,745
group 3 medulloblastoma 10 | 2,254
group 4 medulloblastoma 10 | 1,875
pituitary cancer 10 | 1,972
Carcinoma 9 | 2,147
colon cancer 9 | 1,475
diabetes mellitus 9 | 1,663
ependymoma 9 | 2,514
Pick disease 8 | 1,893
astrocytoma 8 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
posterior fossa group A ependymoma 8 | 1,511
Mammary Neoplasms 7 | 410
Osteoarthritis 7 | 96
Rheumatoid Arthritis 7 | 1,160
acute quadriplegic myopathy 7 | 1,157
juvenile dermatomyositis 7 | 1,189
primitive neuroectodermal tumor 7 | 3,031
sonic hedgehog group medulloblastoma 7 | 1,482
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 1,557
ulcerative colitis 7 | 2,087
Cleft palate 6 | 125
Kidney disease 6 | 396
Liver Cirrhosis, Experimental 6 | 108
Liver carcinoma 6 | 217
Obesity 6 | 616
adult high grade glioma 6 | 2,148
astrocytic glioma 6 | 2,241
posterior fossa group B ependymoma 6 | 1,530
primary pancreatic ductal adenocarcinoma 6 | 1,271
spina bifida 6 | 1,064
Amyotrophic Lateral Sclerosis 5 | 431
Craniofacial Abnormalities 5 | 147
Degenerative polyarthritis 5 | 93
Down syndrome 5 | 548
Endometriosis 5 | 535
Osteoporosis 5 | 257
Parkinson's disease 5 | 364
Pulmonary Fibrosis 5 | 66
Stomach Neoplasms 5 | 282
active Crohn's disease 5 | 918
fibroadenoma 5 | 557
gastric carcinoma 5 | 832
pre-eclampsia 5 | 67
Alzheimer's disease 4 | 644
Ankylosis 4 | 25
Aortic aneurysm 4 | 34
Cleft Lip 4 | 91
Congenital heart disease 4 | 63
Heart disease 4 | 279
Hereditary hemorrhagic telangiectasia 4 | 14
Hypertension 4 | 287
Liver disease 4 | 219
Microphthalmia 4 | 78
Pneumonia 4 | 133
Polycystic Ovary Syndrome 4 | 332
Premature ovarian failure 4 | 64
Prostatic Neoplasms 4 | 471
Ureteral disease 4 | 23
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567
Arthritis 3 | 248
Atopic dermatitis 3 | 944
Craniosynostosis 3 | 47
Duchenne muscular dystrophy 3 | 602
Juvenile arthritis 3 | 124
Proliferative vitreoretinopathy 3 | 17
Reperfusion Injury 3 | 84
esophageal adenocarcinoma 3 | 737
head and neck cancer 3 | 270
nephrosclerosis 3 | 329
tuberculosis and treatment for 6 months 3 | 686

Tissue

Nervous System 57 | 18,561
Endocrine System 56 | 18,512
Male tissues 56 | 17,969
Digestive Tract 55 | 18,473
Female tissues 55 | 18,647
Skin and soft tissues 55 | 18,115
Cardiovascular System 54 | 17,958
Liver and Pancreas 54 | 18,136
Urinary Tract 54 | 18,444
Respiratory system 53 | 17,484
Blood and immune system 51 | 17,995

Target Family

Non-IDG 41 | 11,971
Transcription Factor 11 | 1,400
Enzyme 2 | 4,146
Kinase 2 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

SMAD protein signal transducti... 58 | 58
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Bone morphogenetic protein 1 BMP1 Tchem Non-IDG -2.32178 220.1 155
Alpha-fetoprotein AFP Tbio Non-IDG -4.04711 11505.1 1715
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.59556 4267.5 575
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.05811 121.9 331
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.16723 1539.5 438
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.48343 339.1 259
Bone morphogenetic protein 5 BMP5 Tbio Non-IDG -1.86833 72.6 301
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.03840 1043.2 1391
Nodal homolog NODAL Tbio Non-IDG -2.95956 930.3 232