Development Level

Tbio 49 | 11,651
Tchem 7 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
hypoactivity 3 | 132
decreased body weight 2 | 161
decreased vertical activity 2 | 208
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
decreased B cell number 1 | 5
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased granulocyte number 1 | 1
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total retina thickne... 1 | 4
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 38 | 11,493
ovarian cancer 30 | 8,520
psoriasis 30 | 6,694
osteosarcoma 23 | 7,950
glioblastoma 22 | 5,792
lung cancer 22 | 4,740
Cancer 20 | 2,499
atypical teratoid / rhabdoid tumor 20 | 5,112
medulloblastoma, large-cell 18 | 6,241
Breast cancer 17 | 3,578
ependymoma 17 | 4,679
group 3 medulloblastoma 16 | 4,104
adult high grade glioma 14 | 3,801
malignant mesothelioma 14 | 3,232
Astrocytoma, Pilocytic 13 | 3,081
cystic fibrosis 12 | 1,696
interstitial cystitis 12 | 2,312
invasive ductal carcinoma 12 | 2,951
oligodendroglioma 12 | 2,850
breast carcinoma 11 | 1,638
diabetes mellitus 11 | 1,728
lung adenocarcinoma 11 | 2,716
pancreatic cancer 11 | 2,398
Liver Cirrhosis, Experimental 10 | 769
Osteoarthritis 10 | 184
ductal carcinoma in situ 10 | 1,745
group 4 medulloblastoma 10 | 1,855
lung carcinoma 10 | 2,843
non-small cell lung cancer 10 | 2,890
pituitary cancer 10 | 1,972
Kidney cancer 9 | 2,613
colon cancer 9 | 1,478
Autosomal recessive predisposition 8 | 1,442
Pick disease 8 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Acquired scoliosis 7 | 281
Brachydactyly 7 | 156
Breast Neoplasms 7 | 445
Curvature of spine 7 | 282
Hypertensive disease 7 | 292
Mammary Neoplasms 7 | 425
Orbital separation excessive 7 | 244
Rheumatoid arthritis 7 | 1,191
acute quadriplegic myopathy 7 | 1,158
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
juvenile dermatomyositis 7 | 1,187
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Carcinoma, Hepatocellular 6 | 228
Cleft Palate 6 | 271
Kidney disease 6 | 430
Liver carcinoma 6 | 240
Schizophrenia 6 | 1,160
Short stature 6 | 531
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Acquired flat foot 5 | 72
Amyotrophic lateral sclerosis 5 | 451
Bilateral fifth finger clinodactyly 5 | 110
Cognitive delay 5 | 608
Congenital deafness 5 | 185
Coronary artery disease 5 | 268
Craniofacial Abnormalities 5 | 151
Curvature of little finger 5 | 110
Deafness 5 | 198
Degenerative polyarthritis 5 | 115
Down syndrome 5 | 499
Dull intelligence 5 | 645
Exophthalmos 5 | 112
Flatfoot 5 | 73
Global developmental delay 5 | 608
Hearing Loss, Partial 5 | 185
Hypertension 5 | 396
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Osteoporosis 5 | 363
Parkinson's disease 5 | 392
Poor school performance 5 | 645
Pre-Eclampsia 5 | 68
Prominent eyes 5 | 96
Prominent globes 5 | 96
Protruding eyes 5 | 96
Pulmonary Fibrosis 5 | 106
Right atrial isomerism 5 | 29
Stomach Neoplasms 5 | 300
Ureteral obstruction 5 | 33
fibroadenoma 5 | 559
gastric carcinoma 5 | 807
hearing impairment 5 | 199
Prostatic Neoplasms 4 | 495
acute myeloid leukemia 4 | 783
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989

Tissue

Endocrine System 57 | 18,159
Female tissues 55 | 17,400
Liver and Pancreas 54 | 16,750
Digestive Tract 53 | 17,369
Male tissues 52 | 17,142
Skin and soft tissues 52 | 17,230
Nervous System 51 | 16,725
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909
Respiratory system 49 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 40 | 12,091
Transcription Factor 11 | 1,400
Enzyme 2 | 4,145
Kinase 2 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

SMAD protein signal transducti... 57 | 57
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone morphogenetic protein 15 BMP15 Tbio Non-IDG -2.33917 221.7 200
Cbp/p300-interacting transactivator 1 CITED1 Tbio Non-IDG -1.74130 57.5 210
Leucyl-cystinyl aminopeptidase LNPEP Tchem Enzyme -2.57244 394.0 103
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.88065 80.4 419
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Nodal homolog NODAL Tbio Non-IDG -3.00545 981.7 245
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Mothers against decapentaplegic homolog 5 SMAD5 Tbio Transcription Factor -2.16078 121.7 359
Hepatocyte nuclear factor 4-alpha HNF4A Tchem Nuclear Receptor -3.19918 1373.3 664