Development Level

Tbio 44 | 11,445
Tchem 21 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 2 | 298
decreased startle reflex 2 | 75
increased circulating glucose ... 2 | 24
prenatal lethality 2 | 28
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased body temperature 1 | 9
increased circulating iron lev... 1 | 30
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
limb grasping 1 | 41
small seminal vesicle 1 | 10
small testis 1 | 58
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 51 | 11,493
ovarian cancer 47 | 8,520
osteosarcoma 40 | 7,950
medulloblastoma, large-cell 35 | 6,241
Cancer 33 | 2,499
glioblastoma 33 | 5,792
lung cancer 31 | 4,740
psoriasis 31 | 6,694
ependymoma 30 | 4,679
atypical teratoid / rhabdoid tumor 26 | 5,112
malignant mesothelioma 22 | 3,232
Breast cancer 21 | 3,578
group 3 medulloblastoma 20 | 4,104
invasive ductal carcinoma 20 | 2,951
oligodendroglioma 19 | 2,850
adult high grade glioma 17 | 3,801
pancreatic cancer 17 | 2,398
Kidney cancer 16 | 2,613
astrocytic glioma 16 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung adenocarcinoma 15 | 2,716
primitive neuroectodermal tumor 15 | 3,035
group 4 medulloblastoma 14 | 1,855
Intellectual disability 13 | 1,016
Schizophrenia 13 | 1,160
adrenocortical carcinoma 13 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
non-small cell lung cancer 13 | 2,890
subependymal giant cell astrocytoma 13 | 2,287
breast carcinoma 12 | 1,638
ductal carcinoma in situ 12 | 1,745
ulcerative colitis 12 | 1,819
Astrocytoma, Pilocytic 11 | 3,081
Short stature 11 | 531
acute quadriplegic myopathy 11 | 1,158
astrocytoma 11 | 1,146
lung carcinoma 11 | 2,843
Lung Neoplasms 10 | 232
Rheumatoid arthritis 10 | 1,191
diabetes mellitus 10 | 1,728
juvenile dermatomyositis 10 | 1,187
tuberculosis 10 | 2,010
Autosomal recessive predisposition 9 | 1,442
Blepharoptosis 9 | 231
Dull intelligence 9 | 645
Low intelligence 9 | 645
Melanoma 9 | 711
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
interstitial cystitis 9 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pediatric high grade glioma 9 | 1,064
pituitary cancer 9 | 1,972
Adenoma 8 | 167
Congenital Epicanthus 8 | 177
Low set ears 8 | 181
Muscle hypotonia 8 | 571
Noonan syndrome 8 | 34
Orbital separation excessive 8 | 244
Parkinson's disease 8 | 392
Short neck 8 | 140
Stomach Neoplasms 8 | 300
Bladder Neoplasm 7 | 112
Breast Neoplasms 7 | 445
Cryptorchidism 7 | 296
Delayed bone age 7 | 136
Endometriosis 7 | 540
Epilepsy 7 | 792
Hypertrophic Cardiomyopathy 7 | 117
Hypoplastic mandible condyle 7 | 275
Liver cancer 7 | 604
Mammary Neoplasms 7 | 425
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Neck webbing 7 | 35
Strabismus 7 | 270
Urinary Bladder Neoplasms 7 | 114
Waldenstrons macroglobulinemia 7 | 765
primary Sjogren syndrome 7 | 735
primary pancreatic ductal adenocarcinoma 7 | 1,109
spina bifida 7 | 1,074
Alzheimer's disease 6 | 658
Attention deficit hyperactivity disorder 6 | 278
Cognitive delay 6 | 608
Depressive disorder 6 | 409
Global developmental delay 6 | 608
Heart disease 6 | 306
Low-set, posteriorly rotated ears 6 | 110
Mental and motor retardation 6 | 608
Multiple myeloma 6 | 1,332
Prostatic Neoplasms 6 | 495
Seizures 6 | 596
Vascular disease 6 | 319
Ventricular Septal Defects 6 | 119
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
hepatocellular carcinoma 6 | 547
nasopharyngeal carcinoma 6 | 1,058

Tissue

Digestive Tract 67 | 17,369
Endocrine System 67 | 18,159
Female tissues 67 | 17,400
Nervous System 67 | 16,725
Skin and soft tissues 67 | 17,230
Blood and immune system 66 | 16,909
Cardiovascular System 66 | 15,192
Liver and Pancreas 66 | 16,750
Male tissues 66 | 17,142
Respiratory system 66 | 16,393
Urinary Tract 66 | 16,678

Target Family

Non-IDG 29 | 12,091
Enzyme 23 | 4,145
Kinase 9 | 634
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
TF/Epigenetic 1 | 38

GO Process

Ras protein signal transductio... 68 | 68
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Insulin-like growth factor I IGF1 Tbio Non-IDG -4.32790 22748.0 913
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -4.00542 10573.5 798
Transcription factor AP-1 JUN Tchem Transcription Factor -3.83935 6236.4 2664
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574