Development Level

Tbio 127 | 11,651
Tdark 33 | 6,593
Tchem 9 | 1,388

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 22 | 979
abnormal behavior 5 | 298
embryonic lethality prior to t... 5 | 278
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
abnormal coat-hair pigmentatio... 3 | 64
decreased grip strength 3 | 116
hyperactivity 3 | 148
increased startle reflex 3 | 112
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased neutrophil cell numb... 2 | 42
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased vertical activity 2 | 24
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
aorta dilation 1 | 3
cataract 1 | 92
decreased IgE level 1 | 6
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased circulating phosphat... 1 | 27
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
hydrometra 1 | 53
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 111 | 11,493
ovarian cancer 104 | 8,520
osteosarcoma 73 | 7,950
medulloblastoma, large-cell 65 | 6,241
glioblastoma 57 | 5,792
group 3 medulloblastoma 54 | 4,104
atypical teratoid / rhabdoid tumor 52 | 5,112
psoriasis 52 | 6,694
lung cancer 49 | 4,740
ependymoma 42 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
oligodendroglioma 33 | 2,850
Kidney cancer 32 | 2,613
adult high grade glioma 32 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
acute quadriplegic myopathy 31 | 1,158
astrocytic glioma 31 | 2,597
primitive neuroectodermal tumor 30 | 3,035
malignant mesothelioma 29 | 3,232
Breast cancer 27 | 3,578
Multiple myeloma 27 | 1,332
Pick disease 25 | 1,894
dermatomyositis 25 | 966
subependymal giant cell astrocytoma 24 | 2,287
diabetes mellitus 23 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
invasive ductal carcinoma 22 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
non-small cell lung cancer 21 | 2,890
Astrocytoma, Pilocytic 20 | 3,081
astrocytoma 20 | 1,146
lung adenocarcinoma 19 | 2,716
juvenile dermatomyositis 18 | 1,187
Intellectual disability 17 | 1,016
progressive supranuclear palsy 16 | 676
Rheumatoid arthritis 15 | 1,191
Waldenstrons macroglobulinemia 15 | 765
acute myeloid leukemia 14 | 783
Cancer 13 | 2,499
group 4 medulloblastoma 13 | 1,855
pancreatic cancer 12 | 2,398
pediatric high grade glioma 12 | 1,064
pituitary cancer 12 | 1,972
tuberculosis and treatment for 6 months 12 | 409
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
breast carcinoma 11 | 1,638
Amyotrophic lateral sclerosis 9 | 451
colon cancer 9 | 1,478
lung carcinoma 9 | 2,843
non primary Sjogren syndrome sicca 9 | 891
tuberculosis 9 | 2,010
Anteverted nostril 8 | 191
Conductive hearing loss 8 | 123
Gaucher disease type 1 8 | 180
Hypogonadism 8 | 173
Schizophrenia 8 | 1,160
Nystagmus 7 | 317
hereditary spastic paraplegia 7 | 318
nasopharyngeal carcinoma 7 | 1,058
Broad flat nasal bridge 6 | 236
Cataract 6 | 297
Epilepsy 6 | 792
Glaucoma 6 | 239
Lens Opacities 6 | 231
Nasal bridge wide 6 | 236
Obesity 6 | 678
Short stature 6 | 531
aldosterone-producing adenoma 6 | 665
primary pancreatic ductal adenocarcinoma 6 | 1,109
Abnormality of retinal pigmentation 5 | 111
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
Blind Vision 5 | 111
Blindness, Legal 5 | 110
Cleft Palate 5 | 271
Cognitive delay 5 | 608
Congenital hypoplasia of penis 5 | 176
Down syndrome 5 | 499
Electroretinogram abnormal 5 | 95
Global developmental delay 5 | 608
HIV Infections 5 | 102
Hyperinsulinism 5 | 133
Hypoplastic mandible condyle 5 | 275
Low set ears 5 | 181
Mandibular hypoplasia 5 | 275
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Ophthalmoplegia 5 | 106
Optic Atrophy 5 | 242
Retinal pigment epithelial abnormality 5 | 111
Retinitis Pigmentosa 5 | 226
Sensorineural Hearing Loss (disorder) 5 | 284
Small head 5 | 374
Uranostaphyloschisis 5 | 167
ductal carcinoma in situ 5 | 1,745
spina bifida 5 | 1,074

Tissue

Endocrine System 168 | 18,159
Male tissues 165 | 17,142
Female tissues 164 | 17,400
Urinary Tract 164 | 16,678
Digestive Tract 163 | 17,369
Nervous System 163 | 16,725
Respiratory system 163 | 16,393
Skin and soft tissues 162 | 17,230
Liver and Pancreas 161 | 16,750
Blood and immune system 159 | 16,909
Cardiovascular System 158 | 15,192

Target Family

Non-IDG 139 | 12,091
Enzyme 22 | 4,145
Kinase 4 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

GO Process

RNA splicing 169 | 169
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
RNA-binding protein 39 RBM39 Tbio Non-IDG -0.95639 9.80 199
RNA binding protein fox-1 homolog 1 RBFOX1 Tbio Non-IDG -2.00815 99.2 207
Protein ecdysoneless homolog ECD Tbio Non-IDG -0.72245 9.93 113
Corepressor interacting with RBPJ 1 CIR1 Tdark Non-IDG -0.30821 2.08 91
Serine/threonine-protein phosphatase 4 regulatory subunit 2 PPP4R2 Tbio Enzyme -0.78829 5.38 130
Probable ATP-dependent RNA helicase DDX23 DDX23 Tbio Enzyme -1.24669 18.6 167
Splicing regulatory glutamine/lysine-rich protein 1 SREK1 Tbio Non-IDG -0.53095 4.77 51
Protein quaking QKI Tbio Non-IDG -1.88311 75.1 278
Nuclear cap-binding protein subunit 2 NCBP2 Tbio Non-IDG -1.45099 24.2 110