Development Level

Tbio 121 | 11,178
Tdark 33 | 6,569
Tchem 15 | 1,885

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 22 | 979
abnormal behavior 5 | 298
embryonic lethality prior to t... 5 | 278
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
abnormal coat-hair pigmentatio... 3 | 64
decreased grip strength 3 | 116
hyperactivity 3 | 148
increased startle reflex 3 | 112
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased neutrophil cell numb... 2 | 42
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased vertical activity 2 | 24
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
aorta dilation 1 | 3
cataract 1 | 92
decreased IgE level 1 | 6
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased circulating phosphat... 1 | 27
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
hydrometra 1 | 53
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 110 | 11,192
ovarian cancer 103 | 8,297
osteosarcoma 71 | 7,766
medulloblastoma, large-cell 64 | 6,086
glioblastoma 56 | 5,635
group 3 medulloblastoma 53 | 4,002
atypical teratoid / rhabdoid tumor 51 | 4,971
psoriasis 51 | 6,514
lung cancer 48 | 4,607
ependymoma 42 | 4,559
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,902
Kidney cancer 32 | 2,548
adult high grade glioma 32 | 3,701
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,872
oligodendroglioma 32 | 2,768
astrocytic glioma 31 | 2,530
acute quadriplegic myopathy 30 | 1,133
primitive neuroectodermal tumor 29 | 2,957
malignant mesothelioma 28 | 3,135
Breast cancer 26 | 3,469
Multiple myeloma 26 | 1,296
Pick disease 25 | 1,856
dermatomyositis 24 | 941
subependymal giant cell astrocytoma 24 | 2,230
diabetes mellitus 23 | 1,683
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,204
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,911
invasive ductal carcinoma 21 | 2,867
Astrocytoma, Pilocytic 20 | 3,006
non-small cell lung cancer 20 | 2,799
astrocytoma 19 | 1,113
juvenile dermatomyositis 18 | 1,147
lung adenocarcinoma 18 | 2,627
Intellectual disability 17 | 998
progressive supranuclear palsy 16 | 656
Rheumatoid arthritis 15 | 1,156
Waldenstrons macroglobulinemia 14 | 742
acute myeloid leukemia 14 | 760
Cancer 13 | 2,388
group 4 medulloblastoma 13 | 1,806
pancreatic cancer 12 | 2,322
pituitary cancer 12 | 1,915
Dull intelligence 11 | 634
Low intelligence 11 | 634
Mental Retardation 11 | 634
Mental deficiency 11 | 634
Poor school performance 11 | 634
breast carcinoma 11 | 1,589
pediatric high grade glioma 11 | 1,035
tuberculosis and treatment for 6 months 11 | 399
colon cancer 9 | 1,428
lung carcinoma 9 | 2,755
tuberculosis 9 | 1,963
Amyotrophic lateral sclerosis 8 | 437
Anteverted nostril 8 | 186
Conductive hearing loss 8 | 122
Gaucher disease type 1 8 | 177
Hypogonadism 8 | 169
Schizophrenia 8 | 1,136
non primary Sjogren syndrome sicca 8 | 861
Nystagmus 7 | 309
hereditary spastic paraplegia 7 | 313
nasopharyngeal carcinoma 7 | 1,024
Broad flat nasal bridge 6 | 232
Cataract 6 | 290
Epilepsy 6 | 775
Glaucoma 6 | 232
Lens Opacities 6 | 227
Nasal bridge wide 6 | 232
Obesity 6 | 655
Short stature 6 | 514
aldosterone-producing adenoma 6 | 646
primary pancreatic ductal adenocarcinoma 6 | 1,071
Abnormality of retinal pigmentation 5 | 109
Alzheimer's disease 5 | 640
Autosomal recessive predisposition 5 | 1,407
Blind Vision 5 | 110
Blindness, Legal 5 | 109
Cleft Palate 5 | 265
Cognitive delay 5 | 596
Congenital hypoplasia of penis 5 | 168
Electroretinogram abnormal 5 | 94
Global developmental delay 5 | 596
HIV Infections 5 | 94
Hyperinsulinism 5 | 128
Hypoplastic mandible condyle 5 | 273
Keratoconus 5 | 111
Low set ears 5 | 178
Mandibular hypoplasia 5 | 273
Mental and motor retardation 5 | 596
Micrognathism 5 | 273
Ophthalmoplegia 5 | 105
Optic Atrophy 5 | 239
Retinal pigment epithelial abnormality 5 | 109
Retinitis Pigmentosa 5 | 223
Sensorineural Hearing Loss (disorder) 5 | 281
Small head 5 | 366
Uranostaphyloschisis 5 | 162
ductal carcinoma in situ 5 | 1,686
spina bifida 5 | 1,053

Tissue

Endocrine System 168 | 18,159
Male tissues 165 | 17,142
Female tissues 164 | 17,400
Urinary Tract 164 | 16,678
Digestive Tract 163 | 17,369
Nervous System 163 | 16,725
Respiratory system 163 | 16,393
Skin and soft tissues 162 | 17,230
Liver and Pancreas 161 | 16,750
Blood and immune system 159 | 16,909
Cardiovascular System 158 | 15,192

Target Family

Non-IDG 139 | 12,091
Enzyme 22 | 4,145
Kinase 4 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

GO Process

RNA splicing 169 | 169
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase-binding protein 1 MAPKBP1 Tbio Enzyme -0.46630 4.01 51
RNA-binding motif protein, Y chromosome, family 1 member D RBMY1D Tdark Non-IDG -0.68793 6.70 32
RNA-binding protein 20 RBM20 Tbio Non-IDG -1.40778 24.2 73
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 DHX16 Tbio Enzyme -1.51980 31.4 78
Serine/arginine-rich splicing factor 7 SRSF7 Tbio Non-IDG -1.19691 12.9 177
RNA-binding motif protein, Y chromosome, family 1 member F/J RBMY1J Tdark Non-IDG 0.31 0.53 49
Splicing factor 3B subunit 4 SF3B4 Tbio Non-IDG -1.44416 28.7 222
Splicing factor 3B subunit 3 SF3B3 Tchem Non-IDG -1.28872 19.5 222
Pre-mRNA-processing factor 17 CDC40 Tbio Non-IDG -1.37680 24.3 102