Development Level

Tbio 108 | 10,625
Tdark 36 | 7,003
Tchem 14 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
abnormal behavior 4 | 226
embryonic lethality prior to t... 4 | 187
decreased grip strength 3 | 123
hyperactivity 3 | 108
abnormal coat/hair pigmentatio... 2 | 54
embryonic lethality prior to o... 2 | 148
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
thrombocytosis 2 | 23
abnormal bone structure 1 | 131
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal neural tube morpholog... 1 | 8
abnormal sleep behavior 1 | 63
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
aorta dilation 1 | 3
decreased IgG2b level 1 | 1
decreased body length 1 | 108
decreased circulating alkaline... 1 | 41
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased memory-marker CD4-ne... 1 | 4
decreased neutrophil cell numb... 1 | 37
immune system phenotype 1 | 17
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased CD4-negative NK T ce... 1 | 4
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased coping response 1 | 3
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38

Disease

ovarian cancer 101 | 8,484
osteosarcoma 68 | 7,933
medulloblastoma, large-cell 57 | 6,234
glioblastoma 52 | 5,572
psoriasis 46 | 6,685
lung cancer 45 | 4,466
group 3 medulloblastoma 41 | 2,254
atypical teratoid / rhabdoid tumor 40 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,988
oligodendroglioma 32 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
ependymoma 30 | 2,514
acute quadriplegic myopathy 28 | 1,157
malignant mesothelioma 28 | 3,162
primitive neuroectodermal tumor 27 | 3,031
Multiple myeloma 26 | 1,327
astrocytoma 25 | 1,493
pediatric high grade glioma 25 | 2,712
Pick disease 24 | 1,893
astrocytic glioma 24 | 2,241
dermatomyositis 24 | 933
Breast cancer 22 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
Carcinoma 21 | 2,147
non-small cell lung cancer 21 | 2,798
subependymal giant cell astrocytoma 21 | 2,287
diabetes mellitus 20 | 1,663
invasive ductal carcinoma 20 | 2,950
lung adenocarcinoma 18 | 2,713
adult high grade glioma 17 | 2,148
pilocytic astrocytoma 17 | 3,086
juvenile dermatomyositis 16 | 1,189
progressive supranuclear palsy 16 | 674
Waldenstrons macroglobulinemia 15 | 765
Rheumatoid Arthritis 14 | 1,160
acute myeloid leukemia 14 | 780
Cancer 13 | 2,346
group 4 medulloblastoma 13 | 1,875
tuberculosis and treatment for 6 months 13 | 686
Intellectual disability 12 | 573
atypical teratoid/rhabdoid tumor 12 | 1,095
pituitary cancer 12 | 1,972
pancreatic cancer 11 | 2,300
sonic hedgehog group medulloblastoma 11 | 1,482
breast carcinoma 10 | 1,614
non primary Sjogren syndrome sicca 9 | 840
posterior fossa group A ependymoma 9 | 1,511
Amyotrophic Lateral Sclerosis 8 | 431
colon cancer 8 | 1,475
lung carcinoma 8 | 2,844
Gaucher disease type 1 7 | 171
hereditary spastic paraplegia 7 | 313
nasopharyngeal carcinoma 7 | 1,056
tuberculosis 7 | 1,557
Down syndrome 6 | 548
aldosterone-producing adenoma 6 | 664
posterior fossa group B ependymoma 6 | 1,530
primary pancreatic ductal adenocarcinoma 6 | 1,271
HIV Infections 5 | 100
Retinitis pigmentosa 5 | 153
Schizophrenia 5 | 501
ductal carcinoma in situ 5 | 1,745
spina bifida 5 | 1,064
Alzheimer's disease 4 | 644
Atopic dermatitis 4 | 944
Azoospermia 4 | 89
Duchenne muscular dystrophy 4 | 602
Epilepsy 4 | 346
Lupus erythematosus 4 | 80
Muscular atrophy 4 | 67
Neurodegenerative disease 4 | 383
adrenocortical carcinoma 4 | 1,427
cystic fibrosis 4 | 1,665
gastric carcinoma 4 | 832
medulloblastoma 4 | 1,524
ulcerative colitis 4 | 2,087
Animal Mammary Neoplasms 3 | 136
Becker muscular dystrophy 3 | 187
Cerebrovascular disease 3 | 231
Fragile X syndrome 3 | 31
Gonadoblastoma 3 | 27
IGA Glomerulonephritis 3 | 454
Infertility 3 | 163
Malaria 3 | 140
Mammary Neoplasms, Experimental 3 | 150
Myotonic dystrophy type 1 3 | 16
Oligospermia 3 | 30
Sertoli cell-only syndrome 3 | 36
Stomach Neoplasms 3 | 282
Toxic encephalopathy 3 | 131
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
interstitial cystitis 3 | 2,299
mucosa-associated lymphoid tissue lymphoma 3 | 480
primary Sjogren syndrome 3 | 789
Polycystic Ovary Syndrome 2 | 332
chronic lymphosyte leukemia 2 | 232
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 532
inflammatory breast cancer 2 | 404

Tissue

Blood and immune system 157 | 17,995
Female tissues 157 | 18,647
Male tissues 157 | 17,969
Endocrine System 156 | 18,512
Urinary Tract 154 | 18,444
Digestive Tract 153 | 18,473
Cardiovascular System 152 | 17,958
Liver and Pancreas 152 | 18,136
Nervous System 152 | 18,561
Respiratory system 151 | 17,484
Skin and soft tissues 150 | 18,115

Target Family

Non-IDG 134 | 11,971
Enzyme 16 | 4,146
Kinase 4 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

GO Process

RNA splicing 158 | 158
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.25254 1.81 65
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 1.33 95
Pre-mRNA-splicing factor 38A PRPF38A Tdark Non-IDG -0.69167 4.80 72
Putative RNA-binding protein 15B RBM15B Tbio Non-IDG -0.27107 2.59 18
SURP and G-patch domain-containing protein 2 SUGP2 Tdark Non-IDG 0.12 0.80 116
Complement component 1 Q subcomponent-binding protein, mitochondrial C1QBP Tbio Non-IDG -2.51978 332.6 298
Small nuclear ribonucleoprotein-associated protein N SNURF Tbio Non-IDG -1.63253 44.6 100
THO complex subunit 2 THOC2 Tbio Non-IDG -1.88285 76.8 47
U11/U12 small nuclear ribonucleoprotein 48 kDa protein SNRNP48 Tdark Non-IDG 0.00000 57
Eukaryotic initiation factor 4A-III EIF4A3 Tbio Non-IDG -2.21804 176.4 137