Development Level

Tbio 6 | 11,445
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
preweaning lethality, complete... 2 | 979
embryonic lethality prior to t... 1 | 278
increased fasted circulating g... 1 | 76

Disease

Carcinoma 6 | 11,493
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Kidney cancer 3 | 2,613
Liver cancer 2 | 604
acute quadriplegic myopathy 2 | 1,158
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
spina bifida 2 | 1,074
Abnormal blistering of the skin 1 | 54
Abnormal pigmentation 1 | 25
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Abnormality of the pharynx 1 | 19
Adult onset 1 | 82
Alopecia 1 | 115
Amyotrophic lateral sclerosis 1 | 451
Anemia 1 | 365
Anorectal Malformations 1 | 8
Aplasia/Hypoplasia of the skin 1 | 16
Atrophic condition of skin 1 | 25
Blister of skin 1 | 54
Blood Coagulation Disorders 1 | 42
Bone marrow hypocellularity 1 | 20
Cellular immunodeficiency 1 | 17
Cerebral atrophy 1 | 178
Coagulation abnormalities 1 | 27
Decreased platelet count 1 | 111
Dental caries 1 | 164
Dilated ventricles (finding) 1 | 121
Dyskeratosis congenita 1 | 24
Dystrophia unguium 1 | 53
Esophageal Stenosis 1 | 15
Excessive wrinkled skin 1 | 16
Failure to gain weight 1 | 365
Frequent fractures 1 | 53
Generalized hyperpigmentation 1 | 22
Generalized hypopigmentation of hair 1 | 5
Gingival Diseases 1 | 19
HOYERAAL-HREIDARSSON SYNDROME 1 | 6
Heart conduction disease 1 | 83
Hemoglobin low 1 | 124
Hemorrhagic Disorders 1 | 30
Hyperhidrosis disorder 1 | 81
Hyperpigmented macules 1 | 42
Hypodontia 1 | 81
Hypoplastic-absent toenails 1 | 11
Idiopathic pulmonary fibrosis 1 | 23
Immunologic Deficiency Syndromes 1 | 113
Increased fracture rate 1 | 53
Increased sweating 1 | 81
Infantile onset 1 | 238
Intermittent claudication 1 | 20
Large elongated pulp chamber 1 | 14
Leukokeratosis 1 | 19
Leukoplakia, Oral 1 | 20
Malabsorption 1 | 82
Microphthalmia with limb anomalies 1 | 40
Muscle Hypertonia 1 | 88
Myocardial stunning 1 | 8
Neurodegenerative disease 1 | 414
Neutrophil abnormality 1 | 20
Pediatric failure to thrive 1 | 365
Periodontal Diseases 1 | 21
Pharyngitis 1 | 17
Pontocerebellar hypoplasia 1 | 36
Premature canities 1 | 24
Pulmonary Fibrosis 1 | 106
Pulmonary Fibrosis, Idiopathic 1 | 12
Recurrent respiratory infections 1 | 141
Respiratory Syncytial Virus Infections 1 | 5
Rotting teeth 1 | 73
Rough bone trabeculation 1 | 11
Skin Ulcer 1 | 48
Skin bulla 1 | 54
Sparse hair 1 | 59
Sparse scalp hair 1 | 42
Sweating 1 | 81
Taurodontism 1 | 14
Telangiectasia of the skin 1 | 39
Thin, sparse hair 1 | 59
Thrombocytopenia 1 | 197
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
Varying degree of multiple fractures 1 | 53
astrocytoma 1 | 1,146
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
hypopigmented skin patch 1 | 59
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
periodontitis 1 | 293
primary pancreatic ductal adenocarcinoma 1 | 1,109
psoriasis 1 | 6,694
tuberculosis 1 | 2,010

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 3 | 4,145
Non-IDG 3 | 12,091
Kinase 1 | 634

GO Process

RNA phosphodiester bond hydrol... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CCR4-NOT transcription complex subunit 1 CNOT1 Tbio Non-IDG -2.10799 119.0 37
CCR4-NOT transcription complex subunit 2 CNOT2 Tbio Non-IDG -2.83887 627.5 303
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.13482 125.3 51
2',5'-phosphodiesterase 12 PDE12 Tbio Enzyme -1.46115 31.6 90
Target of EGR1 protein 1 TOE1 Tbio Non-IDG -1.37536 23.1 140
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
PAN2-PAN3 deadenylation complex subunit PAN3 PAN3 Tdark Kinase 0.18 0.87 116