Development Level

Tbio 18 | 11,445
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 1 | 298
abnormal clavicle morphology 1 | 6
abnormal pelvic girdle bone mo... 1 | 12
abnormal rib morphology 1 | 10
abnormal spine curvature 1 | 9
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92

Disease

osteosarcoma 15 | 7,950
ovarian cancer 12 | 8,520
Carcinoma 11 | 11,493
psoriasis 9 | 6,694
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
Kidney cancer 6 | 2,613
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
Aicardi-Goutieres syndrome 5 | 19
Astrocytoma, Pilocytic 5 | 3,081
Multiple myeloma 5 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
Breast cancer 4 | 3,578
astrocytoma 4 | 1,146
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
pancreatic cancer 4 | 2,398
Lung Neoplasms 3 | 232
Pick disease 3 | 1,894
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Allergic hypersensitivity disease 2 | 126
Allergic rhinitis 2 | 94
Asthma 2 | 385
Autosomal recessive predisposition 2 | 1,442
Churg-Strauss syndrome 2 | 5
Endometriosis 2 | 540
Eosinophilic esophagitis 2 | 16
Hypereosinophilic syndrome 2 | 71
Liver cancer 2 | 604
Microphthalmia with limb anomalies 2 | 40
Multiple Sclerosis 2 | 540
Rheumatoid arthritis 2 | 1,191
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
ulcerative colitis 2 | 1,819
Adenocarcinoma of lung 1 | 142
Alopecia 1 | 115
Autistic Disorder 1 | 364
Bronchitis 1 | 43
Cataract 4 multiple types 1 | 14
Congenital myasthenic syndrome 7 1 | 2
Decreased platelet count 1 | 111
Degenerative brain disorder 1 | 100
Dilated ventricles (finding) 1 | 121
Disease Models, Animal 1 | 155
Dystonic disease 1 | 106
Eczema herpeticum 1 | 7
Elevated hepatic transaminases 1 | 81
Global developmental delay, severe 1 | 47
Hepatitis C 1 | 94
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Infantile onset 1 | 238
Influenza 1 | 142
Influenza, Human 1 | 51
Leukodystrophy 1 | 55
Liver Cirrhosis, Experimental 1 | 769
Liver diseases 1 | 87
Microcephaly 1 | 166
Nonsyndromic deafness 1 | 142
Pancytopenia 1 | 45
Pontocerebellar hypoplasia 1 | 36
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Severe psychomotor retardation 1 | 47
Slow progression 1 | 89
Supratentorial atrophy 1 | 94
Systemic lupus erythematosus 1 | 194
Thrombocytopenia 1 | 197
Thyrotoxicosis 1 | 38
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Respiratory system 21 | 16,393
Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Female tissues 20 | 17,400
Nervous System 20 | 16,725
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Enzyme 14 | 4,145
Non-IDG 5 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

RNA catabolic process 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Staphylococcal nuclease domain-containing protein 1 SND1 Tbio Epigenetic -2.35812 225.9 175
Ribonuclease H2 subunit B RNASEH2B Tbio Enzyme -1.44354 27.2 128
SID1 transmembrane family member 2 SIDT2 Tbio Non-IDG -1.01249 13.0 81
5'-3' exoribonuclease 2 XRN2 Tbio Enzyme -1.52792 31.8 121
Nuclear inhibitor of protein phosphatase 1 PPP1R8 Tbio Enzyme -2.70517 500.3 281
Serine/threonine-protein kinase 31 STK31 Tchem Kinase -0.73829 6.09 192
Ribonuclease H2 subunit A RNASEH2A Tbio Enzyme -2.17825 146.7 124
Ribonuclease K6 RNASE6 Tbio Enzyme -0.97895 10.0 59
Heterogeneous nuclear ribonucleoprotein D0 HNRNPD Tbio Non-IDG -2.21226 168.2 325
Polyadenylate-binding protein 4 PABPC4 Tbio Non-IDG -0.92422 8.32 150