Development Level

Tchem 8 | 1,598
Tbio 4 | 11,445

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Cancer 11 | 2,499
ovarian cancer 10 | 8,520
diabetes mellitus 8 | 1,728
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
psoriasis 7 | 6,694
Obesity 6 | 678
Alzheimer's disease 5 | 658
Bipolar Disorder 5 | 666
Carcinoma 5 | 11,493
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Multiple myeloma 5 | 1,332
Vascular disease 5 | 319
cystic fibrosis 5 | 1,696
osteosarcoma 5 | 7,950
pancreatic cancer 5 | 2,398
tuberculosis 5 | 2,010
Fatty Liver 4 | 70
Hyperglycemia 4 | 137
Prostatic Neoplasms 4 | 495
hepatocellular carcinoma 4 | 547
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
non primary Sjogren syndrome sicca 4 | 891
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Squamous Cell 3 | 110
Cerebrovascular disease 3 | 238
Depressive disorder 3 | 409
Endometrial Neoplasms 3 | 55
Endometriosis 3 | 540
Eye disease 3 | 62
Hypertension 3 | 396
Influenza 3 | 142
Liver Cirrhosis 3 | 181
Liver carcinoma 3 | 240
Liver disease 3 | 237
Liver neoplasms 3 | 130
Mental Depression 3 | 333
Pulmonary Fibrosis 3 | 106
Schizophrenia 3 | 1,160
Squamous cell carcinoma 3 | 129
Status Epilepticus 3 | 98
Toxic encephalopathy 3 | 141
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
non-small cell lung carcinoma 3 | 317
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
periodontitis 3 | 293
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Acute kidney injury 2 | 70
Adverse reaction to drug 2 | 61
Alcoholic Intoxication, Chronic 2 | 289
Allergic hypersensitivity disease 2 | 126
Arthritis 2 | 290
Atherosclerosis 2 | 291
Brain Ischemia 2 | 110
Breast Neoplasms 2 | 445
Chemical and Drug Induced Liver Injury 2 | 195
Cholestasis 2 | 155
Coronary artery disease 2 | 268
Dermatitis 2 | 157
Down syndrome 2 | 499
Heart disease 2 | 306
Hyperalgesia 2 | 83
Hypersensitivity reaction type II disease 2 | 253
Infertility 2 | 188
Inflammation 2 | 120
Inflammatory bowel disease 2 | 151
Influenza, Human 2 | 51
Lung disease 2 | 142
Malaria 2 | 160
Mammary Neoplasms 2 | 425
Multiple Sclerosis 2 | 540
Myocardial Ischemia 2 | 169
Necrosis 2 | 53
Parkinson's disease 2 | 392
Peritonitis 2 | 43
Polycystic ovary syndrome 2 | 360
Reperfusion Injury 2 | 86
Vasculitis 2 | 80
adrenocortical adenoma 2 | 131
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
head and neck cancer 2 | 271
nasopharyngeal carcinoma 2 | 1,058

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 6 | 12,091
Transcription Factor 4 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

PERK-mediated unfolded protein... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Asparagine synthetase [glutamine-hydrolyzing] ASNS Tchem Enzyme -2.40144 244.3 223
Nuclear factor erythroid 2-related factor 2 NFE2L2 Tchem Transcription Factor -3.14284 1506.7 552
Cyclic AMP-dependent transcription factor ATF-3 ATF3 Tbio Transcription Factor -2.67021 520.8 401
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.35010 2184.4 1074
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
Insulin-like growth factor-binding protein 1 IGFBP1 Tchem Non-IDG -3.07028 1156.1 425
Cyclic AMP-dependent transcription factor ATF-4 ATF4 Tbio Transcription Factor -2.80910 618.1 809