Development Level

Tbio 49 | 11,651
Tdark 8 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

abnormal retina morphology 1 | 71
abnormal vibrissa morphology 1 | 25
decreased blood urea nitrogen ... 1 | 51
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased bone mineral content 1 | 108
increased lean body mass 1 | 172

Disease

Carcinoma 50 | 11,493
ovarian cancer 31 | 8,520
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
osteosarcoma 24 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
lung adenocarcinoma 23 | 2,716
psoriasis 22 | 6,694
pancreatic cancer 19 | 2,398
Breast cancer 18 | 3,578
lung cancer 17 | 4,740
pituitary cancer 15 | 1,972
cystic fibrosis 14 | 1,696
Astrocytoma, Pilocytic 13 | 3,081
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
active Crohn's disease 11 | 922
ependymoma 11 | 4,679
malignant mesothelioma 11 | 3,232
nasopharyngeal carcinoma 11 | 1,058
non-small cell lung cancer 11 | 2,890
Kidney cancer 10 | 2,613
active ulcerative colitis 10 | 764
Cancer 9 | 2,499
interstitial cystitis 9 | 2,312
invasive ductal carcinoma 9 | 2,951
breast carcinoma 8 | 1,638
group 4 medulloblastoma 8 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
spina bifida 8 | 1,074
Atopic dermatitis 7 | 952
diabetes mellitus 7 | 1,728
esophageal adenocarcinoma 7 | 737
group 3 medulloblastoma 7 | 4,104
lung carcinoma 7 | 2,843
ulcerative colitis 7 | 1,819
Liver cancer 6 | 604
adult high grade glioma 6 | 3,801
ductal carcinoma in situ 6 | 1,745
oligodendroglioma 6 | 2,850
Large intestine cancer 5 | 126
Multiple myeloma 5 | 1,332
colon cancer 5 | 1,478
primary pancreatic ductal adenocarcinoma 5 | 1,109
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 167
Biliary papillomatosis 4 | 4
Endometrial cancer 4 | 311
Melanoma 4 | 711
Otitis Media 4 | 52
astrocytic glioma 4 | 2,597
cutaneous lupus erythematosus 4 | 1,057
interstitial lung disease 4 | 298
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Gastritis 3 | 47
IGA Glomerulonephritis 3 | 50
Immune system cancer 3 | 140
Lymphoid leukemia 3 | 160
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Systemic scleroderma 3 | 60
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
facioscapulohumeral dystrophy 3 | 288
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 336
Bipolar Disorder 2 | 666
Bronchitis 2 | 43
Cardiovascular system disease 2 | 246
Chronic obstructive pulmonary disease 2 | 184
DOID:2627 2 | 94
Influenza 2 | 142
Liver Cirrhosis, Experimental 2 | 769
Multiple Sclerosis 2 | 540
Pick disease 2 | 1,894
Pneumonia 2 | 174
Schizophrenia 2 | 1,160
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
periodontitis 2 | 293
posterior fossa group A ependymoma 2 | 468

Tissue

Digestive Tract 56 | 17,369
Skin and soft tissues 55 | 17,230
Female tissues 54 | 17,400
Blood and immune system 52 | 16,909
Endocrine System 52 | 18,159
Respiratory system 52 | 16,393
Liver and Pancreas 50 | 16,750
Urinary Tract 50 | 16,678
Male tissues 48 | 17,142
Nervous System 47 | 16,725
Cardiovascular System 37 | 15,192

Target Family

Enzyme 41 | 4,145
Non-IDG 18 | 12,091

GO Process

O-glycan processing 59 | 59
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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