Development Level

Tbio 84 | 11,445
Tchem 19 | 1,598
Tclin 5 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
decreased mean corpuscular vol... 3 | 79
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal vertebrae morphology 2 | 18
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
enlarged kidney 2 | 14
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
pale yolk sac 2 | 25
pallor 2 | 34
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal cranium morphology 1 | 36
abnormal duodenum morphology 1 | 4
abnormal eating behavior 1 | 1
abnormal esophagus morphology 1 | 5
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal forced expiratory flo... 1 | 1
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
enlarged gallbladder 1 | 2
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hemorrhage 1 | 23
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
male infertility 1 | 123
premature death 1 | 5
respiratory system phenotype 1 | 2
small spleen 1 | 19
small superior vagus ganglion 1 | 74
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 72 | 11,493
ovarian cancer 57 | 8,520
osteosarcoma 53 | 7,950
medulloblastoma, large-cell 49 | 6,241
psoriasis 49 | 6,694
glioblastoma 48 | 5,792
Cancer 46 | 2,499
ependymoma 46 | 4,679
atypical teratoid / rhabdoid tumor 43 | 5,112
lung cancer 37 | 4,740
Breast cancer 33 | 3,578
malignant mesothelioma 33 | 3,232
group 3 medulloblastoma 32 | 4,104
Astrocytoma, Pilocytic 28 | 3,081
adult high grade glioma 27 | 3,801
lung carcinoma 27 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
astrocytic glioma 25 | 2,597
lung adenocarcinoma 25 | 2,716
primitive neuroectodermal tumor 25 | 3,035
interstitial cystitis 24 | 2,312
oligodendroglioma 24 | 2,850
invasive ductal carcinoma 23 | 2,951
non-small cell lung cancer 23 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Breast Neoplasms 20 | 445
Mammary Neoplasms 20 | 425
pancreatic cancer 19 | 2,398
Kidney cancer 18 | 2,613
Alzheimer's disease 17 | 658
ductal carcinoma in situ 17 | 1,745
cystic fibrosis 16 | 1,696
pituitary cancer 16 | 1,972
acute quadriplegic myopathy 15 | 1,158
pediatric high grade glioma 15 | 1,064
subependymal giant cell astrocytoma 15 | 2,287
Schizophrenia 14 | 1,160
astrocytoma 14 | 1,146
juvenile dermatomyositis 14 | 1,187
Prostatic Neoplasms 13 | 495
Rheumatoid arthritis 13 | 1,191
Short stature 13 | 531
adrenocortical carcinoma 13 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
breast carcinoma 13 | 1,638
diabetes mellitus 13 | 1,728
tuberculosis 13 | 2,010
Pick disease 12 | 1,894
gastric carcinoma 12 | 807
primary pancreatic ductal adenocarcinoma 12 | 1,109
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Lung Neoplasms 11 | 232
colon cancer 11 | 1,478
group 4 medulloblastoma 11 | 1,855
medulloblastoma 11 | 720
Carcinoma, Pancreatic Ductal 10 | 20
Carcinoma, Squamous Cell 10 | 110
Cleft Palate 10 | 271
Failure to gain weight 10 | 365
Pediatric failure to thrive 10 | 365
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Atopic dermatitis 9 | 952
Cataract 9 | 297
Cholestasis 9 | 155
Craniofacial Abnormalities 9 | 151
Duchenne muscular dystrophy 9 | 601
Hypoplastic mandible condyle 9 | 275
Immune system cancer 9 | 140
Lens Opacities 9 | 231
Liver Cirrhosis, Experimental 9 | 769
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Orbital separation excessive 9 | 244
Patent ductus arteriosus 9 | 90
Seizures 9 | 596
Acquired scoliosis 8 | 281
Bipolar Disorder 8 | 666
Brachydactyly 8 | 156
Curvature of spine 8 | 282
Deafness 8 | 198
Epilepsy 8 | 792
Intellectual disability 8 | 1,016
Liver cancer 8 | 604
Liver carcinoma 8 | 240
Lymphoid leukemia 8 | 160
Melanoma 8 | 711
Multiple Sclerosis 8 | 540
Multiple myeloma 8 | 1,332
Skin cancer 8 | 469
Strabismus 8 | 270
acute myeloid leukemia 8 | 783
dermatomyositis 8 | 966
fibroadenoma 8 | 559
Carcinoma, Hepatocellular 7 | 228
Cerebrovascular disease 7 | 238
Ventricular Septal Defects 7 | 119
esophageal adenocarcinoma 7 | 737
spina bifida 7 | 1,074

Tissue

Endocrine System 111 | 18,159
Digestive Tract 110 | 17,369
Skin and soft tissues 110 | 17,230
Urinary Tract 110 | 16,678
Female tissues 109 | 17,400
Liver and Pancreas 108 | 16,750
Male tissues 107 | 17,142
Respiratory system 107 | 16,393
Blood and immune system 106 | 16,909
Nervous System 106 | 16,725
Cardiovascular System 99 | 15,192

Target Family

Non-IDG 52 | 12,091
Transcription Factor 27 | 1,400
Enzyme 25 | 4,145
Epigenetic 3 | 242
Kinase 2 | 634
Nuclear Receptor 2 | 48
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

Notch signaling pathway 113 | 113
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Hairy/enhancer-of-split related with YRPW motif protein 1 HEY1 Tbio Transcription Factor -2.28398 163.4 335
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Notchless protein homolog 1 NLE1 Tbio Non-IDG -2.69934 437.6 162
Probable E3 ubiquitin-protein ligase DTX2 DTX2 Tbio Enzyme -1.74890 58.1 123
Neurogenic differentiation factor 4 NEUROD4 Tbio Transcription Factor -1.14336 11.7 62
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Mesoderm posterior protein 1 MESP1 Tbio Transcription Factor -1.38536 26.8 208
Transcription factor HES-7 HES7 Tbio Transcription Factor -1.36047 22.6 144
Contactin-1 CNTN1 Tbio Non-IDG -1.93017 87.6 211