Development Level

Tbio 9 | 11,445
Tchem 7 | 1,598

IMPC Phenotype

decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
abnormal eating behavior 1 | 1
abnormal embryo size 1 | 220
abnormal forced expiratory flo... 1 | 1
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased tidal volume 1 | 1
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 12 | 11,493
Alzheimer's disease 9 | 658
Cancer 9 | 2,499
osteosarcoma 9 | 7,950
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
atypical teratoid / rhabdoid tumor 7 | 5,112
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Astrocytoma, Pilocytic 6 | 3,081
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
primitive neuroectodermal tumor 6 | 3,035
Dementia 5 | 175
Schizophrenia 5 | 1,160
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
pediatric high grade glioma 5 | 1,064
Breast cancer 4 | 3,578
Carcinoma, Pancreatic Ductal 4 | 20
Neurodegenerative disease 4 | 414
adrenocortical carcinoma 4 | 1,428
diabetes mellitus 4 | 1,728
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
Alzheimer Disease 3 | 83
Amyloidosis 3 | 67
Cadasil 3 | 10
Cerebrovascular disease 3 | 238
Hidradenitis suppurativa 3 | 13
Hidradenitis suppurativa, familial 3 | 3
Kidney cancer 3 | 2,613
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Acne 2 | 52
Adult onset 2 | 82
Aphasia 2 | 26
Asthma 2 | 385
Bipolar Disorder 2 | 666
Brachydactyly 2 | 156
Carcinoma, Squamous Cell 2 | 110
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
Cerebral atrophy 2 | 178
Cerebrovascular accident 2 | 63
Congestive heart failure 2 | 113
Crohn's disease 2 | 321
Depressive disorder 2 | 409
Dilated cardiomyopathy 2 | 56
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Forgetful 2 | 40
Frontotemporal dementia 2 | 51
Heart failure 2 | 162
Hypertension 2 | 396
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Long narrow head 2 | 75
Lung Neoplasms 2 | 232
Memory Loss 2 | 40
Memory impairment 2 | 40
Migraine 2 | 83
Multiple Sclerosis 2 | 540
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Pain agnosia 2 | 104
Pediatric failure to thrive 2 | 365
Pseudobulbar palsy 2 | 11
Seizures 2 | 596
Short distal phalanges 2 | 50
Skin Neoplasms 2 | 69
Strabismus 2 | 270
Syncope 2 | 22
Systemic lupus erythematosus 2 | 194
Tetralogy of Fallot 2 | 63
Turridolichocephaly 2 | 75
Type 1 diabetes mellitus 2 | 109
Ventricular Septal Defects 2 | 119
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Nervous System 15 | 16,725

Target Family

Enzyme 8 | 4,145
Non-IDG 8 | 12,091

GO Process

Notch receptor processing 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypeptide N-acetylgalactosaminyltransferase 11 GALNT11 Tbio Enzyme -0.66996 5.39 88
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
Delta and Notch-like epidermal growth factor-related receptor DNER Tbio Non-IDG -1.65805 49.1 185
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Disintegrin and metalloproteinase domain-containing protein 10 ADAM10 Tchem Enzyme -2.64652 422.4 384
Neurogenic locus notch homolog protein 4 NOTCH4 Tchem Non-IDG -2.75010 557.0 225
Gamma-secretase subunit APH-1B APH1B Tbio Enzyme -1.17035 13.6 56
Protein jagged-1 JAG1 Tbio Non-IDG -3.09216 1190.8 473
Disintegrin and metalloproteinase domain-containing protein 17 ADAM17 Tchem Enzyme -3.55216 3569.0 718
Neurogenic locus notch homolog protein 3 NOTCH3 Tchem Non-IDG -2.67185 458.4 499