Development Level

Tbio 47 | 11,445
Tchem 9 | 1,598
Tclin 5 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal kidney morphology 1 | 65
abnormal skin condition 1 | 6
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
tremors 1 | 39

Disease

ovarian cancer 43 | 8,520
Multiple myeloma 32 | 1,332
lung cancer 30 | 4,740
Carcinoma 29 | 11,493
psoriasis 27 | 6,694
osteosarcoma 23 | 7,950
glioblastoma 21 | 5,792
Cancer 18 | 2,499
HIV Infections 17 | 102
dermatomyositis 14 | 966
Breast cancer 10 | 3,578
Waldenstrons macroglobulinemia 10 | 765
malignant mesothelioma 10 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
tuberculosis 10 | 2,010
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
Mantle cell lymphoma 7 | 23
astrocytoma 7 | 1,146
diabetes mellitus 7 | 1,728
ependymoma 7 | 4,679
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Anemia 5 | 365
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Pick disease 5 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
non primary Sjogren syndrome sicca 5 | 891
pancreatic cancer 5 | 2,398
primary Sjogren syndrome 5 | 735
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Heat Stroke 4 | 13
Osteoporosis 4 | 363
Splenomegaly 4 | 190
acute myeloid leukemia 4 | 783
astrocytic glioma 4 | 2,597
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Atopic dermatitis 3 | 952
Elevated hepatic transaminases 3 | 81
Hepatic enzyme increased 3 | 81
Liver Dysfunction 3 | 99
Liver enzymes abnormal 3 | 81
Liver function test increased 3 | 81
Liver function tests abnormal finding 3 | 81
Lymphadenopathy 3 | 62
Parkinson's disease 3 | 392
Pneumonia 3 | 174
Rheumatoid arthritis 3 | 1,191
Subclinical abnormal liver function tests 3 | 81
Syndactyly of fingers 3 | 48
Transaminases increased 3 | 81
active Crohn's disease 3 | 922
cutaneous lupus erythematosus 3 | 1,057
lung adenocarcinoma 3 | 2,716
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819
Bladder Neoplasm 2 | 112
Brachycephaly 2 | 88
Broad cranium shape 2 | 88
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Epilepsy 2 | 792
Highly variable severity 2 | 157
Hypothyroidism 2 | 122
Inflammatory bowel disease 2 | 151
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Leukemia 2 | 104
Macroglossia 2 | 65
Macrotia 2 | 87
Mood Disorders 2 | 184
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Urinary Bladder Neoplasms 2 | 114
Variable expressivity 2 | 157
Vascular disease 2 | 319
Wide skull shape 2 | 88
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
spina bifida 2 | 1,074

Tissue

Endocrine System 64 | 18,159
Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Nervous System 63 | 16,725
Respiratory system 63 | 16,393
Urinary Tract 63 | 16,678
Cardiovascular System 62 | 15,192
Liver and Pancreas 62 | 16,750
Skin and soft tissues 62 | 17,230

Target Family

Enzyme 40 | 4,145
Non-IDG 17 | 12,091
Transcription Factor 4 | 1,400
Kinase 3 | 634

GO Process

NIK-NF-kappaB signaling 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
26S proteasome regulatory subunit 10B PSMC6 Tbio Enzyme -2.65165 339.0 214
Proteasome subunit alpha type-7 PSMA7 Tbio Enzyme -2.71627 496.7 288
Proteasome subunit alpha type-6 PSMA6 Tbio Enzyme -2.80973 614.4 288