Development Level

Tbio 35 | 10,625
Tchem 21 | 1,890
Tclin 5 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased lean body mass 3 | 195
preweaning lethality, complete... 3 | 633
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal skin condition 1 | 6
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating amylase ... 1 | 24
decreased circulating sodium l... 1 | 18
decreased mean corpuscular hem... 1 | 19
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to o... 1 | 148
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased thermal nociceptive ... 1 | 9
tremors 1 | 34

Disease

ovarian cancer 42 | 8,492
Multiple myeloma 32 | 1,328
lung cancer 28 | 4,473
psoriasis 27 | 6,685
osteosarcoma 23 | 7,933
glioblastoma 21 | 5,572
Cancer 17 | 2,346
HIV Infections 17 | 100
dermatomyositis 14 | 967
Waldenstrons macroglobulinemia 10 | 765
malignant mesothelioma 10 | 3,163
Breast cancer 9 | 3,099
medulloblastoma, large-cell 9 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
tuberculosis 9 | 1,563
atypical teratoid / rhabdoid tumor 8 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
Mantle cell lymphoma 7 | 20
astrocytoma 7 | 1,493
non-small cell lung cancer 7 | 2,798
diabetes mellitus 6 | 1,663
lung carcinoma 6 | 2,844
oligodendroglioma 6 | 2,849
ulcerative colitis 6 | 2,087
Pick disease 5 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
juvenile dermatomyositis 5 | 1,189
non primary Sjogren syndrome sicca 5 | 840
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
primary Sjogren syndrome 5 | 789
subependymal giant cell astrocytoma 5 | 2,287
Heat Stroke 4 | 12
acute myeloid leukemia 4 | 785
astrocytic glioma 4 | 2,241
ependymoma 4 | 2,514
esophageal adenocarcinoma 4 | 737
group 3 medulloblastoma 4 | 2,254
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
pilocytic astrocytoma 4 | 3,086
posterior fossa group A ependymoma 4 | 1,511
primary pancreatic ductal adenocarcinoma 4 | 1,271
Alzheimer's disease 3 | 644
Atopic dermatitis 3 | 944
IGA Glomerulonephritis 3 | 454
Rheumatoid Arthritis 3 | 1,171
active Crohn's disease 3 | 918
cutaneous lupus erythematosus 3 | 1,056
lung adenocarcinoma 3 | 2,714
medulloblastoma 3 | 1,524
progressive supranuclear palsy 3 | 674
Animal Mammary Neoplasms 2 | 136
Bladder Neoplasm 2 | 109
Common variable immunodeficiency 2 | 98
Crohn's disease 2 | 304
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Histoplasmosis 2 | 22
Leukemia 2 | 88
Mammary Neoplasms, Experimental 2 | 150
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Osteoporosis 2 | 259
Parkinson's disease 2 | 364
Peripheral Neuropathy 2 | 303
Pick's disease 2 | 14
Squamous cell carcinoma of esophagus 2 | 82
Stevens-Johnson syndrome 2 | 91
acute quadriplegic myopathy 2 | 1,157
chronic kidney disease 2 | 90
cystic fibrosis 2 | 1,670
group 4 medulloblastoma 2 | 1,875
hepatocellular carcinoma 2 | 550
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686
Acquired metabolic disease 1 | 267
Amyotrophic Lateral Sclerosis 1 | 432
Anemia 1 | 252
Ankylosing spondylitis 1 | 138
Barrett's esophagus 1 | 185
Bipolar Disorder 1 | 266
Brain Ischemia 1 | 87
Cleft palate 1 | 125
Cockayne syndrome 1 | 54
Colonic Neoplasms 1 | 126
Degenerative polyarthritis 1 | 93
Edwards syndrome 1 | 15
Hypertensive retinopathy 1 | 9
Inflammatory bowel disease 1 | 142
Inflammatory dermatosis 1 | 38
Kidney Diseases 1 | 86
Liver diseases 1 | 66
Liver neoplasms 1 | 109
Narcolepsy 1 | 69
Patau syndrome 1 | 15
Stomach Neoplasms 1 | 282
head and neck cancer 1 | 270
sarcoidosis 1 | 368
substance-related disorder 1 | 105

Tissue

Blood and immune system 62 | 17,995
Digestive Tract 62 | 18,473
Endocrine System 62 | 18,512
Female tissues 62 | 18,647
Liver and Pancreas 62 | 18,136
Male tissues 62 | 17,969
Nervous System 62 | 18,561
Urinary Tract 62 | 18,444
Cardiovascular System 61 | 17,958
Respiratory system 61 | 17,484
Skin and soft tissues 61 | 18,115

Target Family

Enzyme 40 | 4,146
Non-IDG 16 | 11,969
Transcription Factor 4 | 1,400
Kinase 2 | 634

GO Process

NIK/NF-kappaB signaling 62 | 62
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Baculoviral IAP repeat-containing protein 3 BIRC3 Tchem Non-IDG -2.60501 360.4 372
Baculoviral IAP repeat-containing protein 2 BIRC2 Tchem Non-IDG -2.51198 295.0 303
Polyubiquitin-C UBC Tbio Non-IDG -2.87696 56.7 130
Polyubiquitin-B UBB Tbio Non-IDG -1.96206 92.3 370
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.86105 71.4 158
26S protease regulatory subunit 6A PSMC3 Tbio Enzyme -1.26468 18.5 271
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.44048 25.4 280
Cullin-1 CUL1 Tbio Non-IDG -2.33531 167.2 343
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.59489 39.3 30
F-box/WD repeat-containing protein 11 FBXW11 Tbio Non-IDG -0.70213 5.61 153