Development Level

Tbio 11 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased total body fat amoun... 2 | 207
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased lactate dehydrogenas... 1 | 16
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hyperactivity 1 | 148
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
persistence of hyaloid vascula... 1 | 33

Disease

ovarian cancer 11 | 8,520
osteosarcoma 10 | 7,950
glioblastoma 7 | 5,792
psoriasis 7 | 6,694
Carcinoma 6 | 11,493
cystic fibrosis 6 | 1,696
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic cancer 5 | 2,398
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
Liver Cirrhosis, Experimental 4 | 769
astrocytic glioma 4 | 2,597
cutaneous lupus erythematosus 4 | 1,057
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
adult high grade glioma 3 | 3,801
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Autosomal recessive predisposition 2 | 1,442
Chronic Lymphocytic Leukemia 2 | 262
Macular degeneration 2 | 65
Major Depressive Disorder 2 | 301
Myocardial Infarction 2 | 151
Pick disease 2 | 1,894
Unipolar Depression 2 | 250
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
Adenocarcinoma of lung 1 | 142
Anemia 1 | 365
Arts syndrome 1 | 26
Barrett's esophagus 1 | 182
Blindness 1 | 88
Breast Neoplasms 1 | 445
Brugada Syndrome (disorder) 1 | 15
Brugada syndrome 1 | 29
COPD 1 | 118
Carcinoma, Renal Cell 1 | 124
Cardiomyopathies 1 | 110
Creatine phosphokinase serum increased 1 | 110
Disease Models, Animal 1 | 155
Elevated creatine kinase 1 | 110
Fatty Liver 1 | 70
Glycogen storage disease 1 | 39
Huntington's disease 1 | 76
Impaired exercise tolerance 1 | 42
Increased serum lactate 1 | 60
Increased serum pyruvate 1 | 9
Kidney Failure 1 | 111
Leber congenital amaurosis 1 | 69
Lung diseases 1 | 50
Mammary Neoplasms 1 | 425
Mood Disorders 1 | 184
Myoglobinuria 1 | 15
Narcolepsy 1 | 72
Neoplasm Invasiveness 1 | 161
Parkinson Disease 1 | 64
Parkinson's disease 1 | 392
Pellagra 1 | 26
Rectal prolapse 1 | 19
Renal Cell Carcinoma 1 | 214
Renal Insufficiency 1 | 90
Renal failure in adulthood 1 | 76
Retinal Degeneration 1 | 106
Rhabdomyolysis 1 | 15
Rickets 1 | 49
Stomach Neoplasms 1 | 300
Systemic lupus erythematosus 1 | 194
Thrombocytopenia 1 | 197
Ventricular Fibrillation 1 | 17
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
non-small cell lung carcinoma 1 | 317
nutritional deficiency disease 1 | 9
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Nervous System 15 | 16,725

Target Family

Enzyme 12 | 4,145
Kinase 4 | 634

GO Process

NAD metabolic process 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide riboside kinase 1 NMRK1 Tbio Kinase -0.84939 6.66 143
Glutamine-dependent NAD(+) synthetase NADSYN1 Tbio Enzyme -1.21917 15.2 60
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 NMNAT2 Tbio Enzyme -1.54038 36.0 111
NAD kinase 2, mitochondrial NADK2 Tbio Kinase -0.81808 8.08 110
Glycerol-3-phosphate dehydrogenase 1-like protein GPD1L Tbio Enzyme -1.31283 20.2 132
NAD kinase NADK Tbio Kinase -1.49880 29.8 98
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 BST1 Tbio Enzyme -1.86410 73.3 284
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 NMNAT3 Tbio Enzyme -1.31765 20.1 141
L-lactate dehydrogenase A chain LDHA Tchem Enzyme -3.03454 1030.5 577