Development Level

Tbio 27 | 11,445
Tchem 18 | 1,598
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal liver size 1 | 5
abnormal outer ear morphology 1 | 3
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
anophthalmia 1 | 33
convulsive seizures 1 | 13
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased startle reflex 1 | 112
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 39 | 11,493
ovarian cancer 27 | 8,520
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 22 | 6,241
glioblastoma 21 | 5,792
ependymoma 16 | 4,679
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 15 | 5,112
Cancer 14 | 2,499
adult high grade glioma 14 | 3,801
lung cancer 14 | 4,740
Kidney cancer 12 | 2,613
astrocytic glioma 12 | 2,597
group 3 medulloblastoma 11 | 4,104
lung carcinoma 11 | 2,843
Astrocytoma, Pilocytic 10 | 3,081
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
group 4 medulloblastoma 9 | 1,855
malignant mesothelioma 9 | 3,232
primitive neuroectodermal tumor 9 | 3,035
acute myeloid leukemia 8 | 783
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
ulcerative colitis 8 | 1,819
Breast cancer 7 | 3,578
Pick disease 7 | 1,894
cystic fibrosis 7 | 1,696
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
Melanoma 6 | 711
Vascular disease 6 | 319
interstitial cystitis 6 | 2,312
tuberculosis 6 | 2,010
Crohn's disease 5 | 321
Dull intelligence 5 | 645
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Osteoporosis 5 | 363
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
Anemia 4 | 365
Arthritis 4 | 290
Blastic phase chronic myeloid leukemia 4 | 58
Cholestasis, Extrahepatic 4 | 25
Chronic Myelocytic Leukemia Accelerated Phase 4 | 59
Coronary artery disease 4 | 268
Diarrhea 4 | 253
Disease Models, Animal 4 | 155
Hypohidrotic ectodermal dysplasia 4 | 15
Kidney disease 4 | 430
Neurodegenerative disease 4 | 414
Parkinson's disease 4 | 392
Reperfusion Injury 4 | 86
Schizophrenia 4 | 1,160
Short stature 4 | 531
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
juvenile dermatomyositis 4 | 1,187
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Arthritis, Rheumatoid 3 | 174
Asthma 3 | 385
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Brain Ischemia 3 | 110
Colitis 3 | 54
Curvature of spine 3 | 282
Depressive disorder 3 | 409
Fatty liver disease 3 | 103
Hyperalgesia 3 | 83
Hyperhomocysteinemia 3 | 37
Hypoplastic mandible condyle 3 | 275
Inflammatory bowel disease 3 | 151
Lung Neoplasms 3 | 232
Mandibular hypoplasia 3 | 275
Mental Depression 3 | 333
Neoplasm Metastasis 3 | 168
Seizures 3 | 596
Toxic encephalopathy 3 | 141
Uveitis 3 | 103
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
esophageal adenocarcinoma 3 | 737
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group A ependymoma 3 | 468
sarcoidosis 3 | 370

Tissue

Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Endocrine System 50 | 18,159
Female tissues 50 | 17,400
Nervous System 50 | 16,725
Urinary Tract 50 | 16,678
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Skin and soft tissues 49 | 17,230
Respiratory system 47 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Kinase 22 | 634
Non-IDG 21 | 12,091
Enzyme 4 | 4,145
GPCR 3 | 408

GO Process

JNK cascade 50 | 50
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 9 DUSP9 Tbio Enzyme -1.15238 17.2 202
Mitogen-activated protein kinase kinase kinase 10 MAP3K10 Tchem Kinase -1.20048 15.1 221
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
SH2 domain-containing protein 3A SH2D3A Tbio Non-IDG -2.47559 291.4 103
Mitogen-activated protein kinase kinase kinase kinase 2 MAP4K2 Tchem Kinase -1.60423 35.3 193
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Mitogen-activated protein kinase kinase kinase 12 MAP3K12 Tchem Kinase -2.06440 121.0 134
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181