Development Level

Tbio 18 | 11,651
Tchem 6 | 1,388
Tclin 4 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 1 | 220
abnormal gait 1 | 69
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating total pr... 1 | 49
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 20 | 8,520
Carcinoma 19 | 11,493
osteosarcoma 15 | 7,950
lung cancer 14 | 4,740
medulloblastoma, large-cell 14 | 6,241
Cancer 13 | 2,499
glioblastoma 13 | 5,792
psoriasis 12 | 6,694
atypical teratoid / rhabdoid tumor 11 | 5,112
Astrocytoma, Pilocytic 10 | 3,081
adult high grade glioma 10 | 3,801
malignant mesothelioma 10 | 3,232
tuberculosis 10 | 2,010
Breast cancer 9 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
Multiple Sclerosis 8 | 540
cutaneous lupus erythematosus 8 | 1,057
ependymoma 8 | 4,679
lung carcinoma 8 | 2,843
Arthritis 7 | 290
Atopic dermatitis 7 | 952
Hepatitis C 7 | 94
Liver Cirrhosis, Experimental 7 | 769
Rheumatoid arthritis 7 | 1,191
Asthma 6 | 385
Kidney cancer 6 | 2,613
Obesity 6 | 678
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pancreatic cancer 6 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Anemia 5 | 365
Hypersensitivity reaction type II disease 5 | 253
Kidney disease 5 | 430
Liver disease 5 | 237
Multiple myeloma 5 | 1,332
Myocardial Ischemia 5 | 169
Pick disease 5 | 1,894
Systemic lupus erythematosus 5 | 194
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
primary Sjogren syndrome 5 | 735
Atherosclerosis 4 | 291
Autosomal recessive predisposition 4 | 1,442
Crohn's disease 4 | 321
Encephalitis 4 | 64
Hepatitis 4 | 67
Inflammation 4 | 120
Inflammatory bowel disease 4 | 151
Influenza 4 | 142
Liver Cirrhosis 4 | 181
Liver diseases 4 | 87
Microphthalmia with limb anomalies 4 | 40
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
head and neck cancer 4 | 271
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
Brain Injuries 3 | 65
Brain Ischemia 3 | 110
Carcinoma, Hepatocellular 3 | 228
Dermatitis 3 | 157
Dermatitis, Allergic Contact 3 | 67
Fever 3 | 138
Kidney Failure 3 | 111
Liver Neoplasms, Experimental 3 | 59
Liver carcinoma 3 | 240
Lung disease 3 | 142
Mastocytosis 3 | 27
Pneumonia 3 | 174
Polycythemia vera 3 | 27
Primary polycythemia 3 | 8
Prostatic Neoplasms 3 | 495
Reperfusion Injury 3 | 86
Schizophrenia 3 | 1,160
Short stature 3 | 531
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
Wide nose 3 | 35
active Crohn's disease 3 | 922
astrocytic glioma 3 | 2,597
group 3 medulloblastoma 3 | 4,104
hepatocellular carcinoma 3 | 547
non diabetic and post-ischemic heart failure 3 | 200
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Hepatitis B 2 | 108
Major Depressive Disorder 2 | 301
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76

Tissue

Endocrine System 28 | 18,159
Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Cardiovascular System 25 | 15,192
Female tissues 25 | 17,400
Male tissues 25 | 17,142
Urinary Tract 25 | 16,678
Nervous System 24 | 16,725

Target Family

Non-IDG 17 | 12,091
Transcription Factor 7 | 1,400
Enzyme 1 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

JAK-STAT cascade 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.06548 1112.4 530
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Signal transducer and activator of transcription 2 STAT2 Tbio Transcription Factor -2.43127 248.8 691
Signal transducer and activator of transcription 4 STAT4 Tbio Transcription Factor -2.51382 320.4 790
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.05851 1163.8 469
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.93311 79.5 268
Interferon lambda-1 IFNL1 Tbio Non-IDG -1.98058 96.1 168
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620
Interleukin-31 receptor subunit alpha IL31RA Tbio Non-IDG -2.90107 764.5 192
Suppressor of cytokine signaling 6 SOCS6 Tbio Non-IDG -1.92284 79.5 154