Development Level

Tbio 39 | 10,625
Tchem 9 | 1,890
Tdark 7 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
embryonic lethality prior to t... 3 | 187
abnormal bone mineralization 2 | 55
decreased body weight 2 | 174
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
short tibia 2 | 82
abnormal bone structure 1 | 131
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal seminal vesicle morph... 1 | 47
absent vibrissae 1 | 14
decreased IgG1 level 1 | 4
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
enlarged heart 1 | 111
hyperactivity 1 | 108
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
vertebral fusion 1 | 23

Disease

ovarian cancer 38 | 8,484
osteosarcoma 33 | 7,933
glioblastoma 26 | 5,572
psoriasis 23 | 6,685
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
medulloblastoma, large-cell 19 | 6,234
lung cancer 18 | 4,466
atypical teratoid / rhabdoid tumor 16 | 4,369
Multiple myeloma 15 | 1,327
diabetes mellitus 14 | 1,663
pediatric high grade glioma 14 | 2,712
lung adenocarcinoma 12 | 2,713
non-small cell lung cancer 12 | 2,798
Breast cancer 11 | 3,094
astrocytoma 11 | 1,493
ependymoma 11 | 2,514
acute quadriplegic myopathy 10 | 1,157
group 3 medulloblastoma 10 | 2,254
lung carcinoma 10 | 2,844
pancreatic cancer 10 | 2,300
pilocytic astrocytoma 10 | 3,086
invasive ductal carcinoma 9 | 2,950
subependymal giant cell astrocytoma 9 | 2,287
active Crohn's disease 8 | 918
tuberculosis 8 | 1,557
Cancer 7 | 2,346
group 4 medulloblastoma 7 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
juvenile dermatomyositis 7 | 1,189
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,031
Neurodegenerative disease 6 | 383
Pick disease 6 | 1,893
malignant mesothelioma 6 | 3,162
posterior fossa group B ependymoma 6 | 1,530
Rheumatoid Arthritis 5 | 1,160
adult high grade glioma 5 | 2,148
astrocytic glioma 5 | 2,241
dermatomyositis 5 | 933
non primary Sjogren syndrome sicca 5 | 840
oligodendroglioma 5 | 2,849
Alzheimer's disease 4 | 644
Obesity 4 | 616
colon cancer 4 | 1,475
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
Carcinoma 3 | 2,147
Cardiomyopathy 3 | 110
Epilepsy 3 | 346
Myopathy 3 | 128
Polycystic Ovary Syndrome 3 | 332
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,427
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
hepatocellular carcinoma 3 | 532
medulloblastoma 3 | 1,524
pancreatic carcinoma 3 | 567
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
ulcerative colitis 3 | 2,087
AMYOTROPHIC LATERAL SCLEROSIS 1 2 | 49
Amyotrophic lateral sclerosis type 8 2 | 8
Barrett's esophagus 2 | 183
Bipolar Disorder 2 | 266
COPD 2 | 113
Cardiomyopathy, Dilated 2 | 47
Charcot-Marie-Tooth disease 2 | 74
Craniofacial Abnormalities 2 | 147
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Duchenne muscular dystrophy 2 | 602
Essential Hypertension 2 | 82
Fatty liver disease 2 | 84
Hyperglycemia 2 | 120
Liver carcinoma 2 | 217
Neuropathy 2 | 210
Parkinson's disease 2 | 364
Prostatic Neoplasms 2 | 471
Rett syndrome 2 | 18
SPINOCEREBELLAR ATAXIA 17 2 | 9
Squamous cell carcinoma of esophagus 2 | 82
Type 2 diabetes mellitus 2 | 189
Vascular disease 2 | 281
X-linked cerebral adrenoleukodystrophy 2 | 115
acute myeloid leukemia 2 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 430
gastric carcinoma 2 | 832
mucosa-associated lymphoid tissue lymphoma 2 | 480
progressive supranuclear palsy 2 | 674
sarcoidosis 2 | 358
tuberculosis and treatment for 6 months 2 | 686
Bacterial vaginosis 1 | 15
Chlamydia 1 | 18
Optic atrophy 1 | 43
Syphilis 1 | 18

Tissue

Blood and immune system 56 | 17,995
Cardiovascular System 56 | 17,958
Digestive Tract 56 | 18,473
Endocrine System 56 | 18,512
Female tissues 56 | 18,647
Liver and Pancreas 56 | 18,136
Male tissues 56 | 17,969
Nervous System 56 | 18,561
Respiratory system 56 | 17,484
Skin and soft tissues 56 | 18,115
Urinary Tract 56 | 18,444

Target Family

Non-IDG 29 | 11,971
Enzyme 20 | 4,146
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Kinase 2 | 634

GO Process

IRE1-mediated unfolded protein... 56 | 56
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein transport protein Sec61 subunit alpha isoform 1 SEC61A1 Tbio Non-IDG -2.43916 280.2 94
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.28487 2003.3 918
Protein transport protein Sec61 subunit gamma SEC61G Tdark Non-IDG -0.37727 2.21 27
Glycogen synthase kinase-3 alpha GSK3A Tclin Kinase -1.81647 52.3 722
Exostosin-like 3 EXTL3 Tbio Enzyme -2.64135 453.0 177
Hepatoma-derived growth factor HDGF Tbio Epigenetic -2.04271 125.7 182
Wolframin WFS1 Tbio Non-IDG -2.36163 250.2 110
Protein transport protein Sec31A SEC31A Tbio Non-IDG -1.13880 12.4 72
Stress-associated endoplasmic reticulum protein 1 SERP1 Tbio Non-IDG -1.35469 29.5 75
Sulfotransferase 1A3 SULT1A3 Tchem Enzyme -2.34317 249.1 106