Development Level

Tbio 33 | 10,625
Tchem 17 | 1,890
Tclin 5 | 602
Tdark 4 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
absent vibrissae 2 | 14
abnormal behavior 1 | 226
abnormal cornea morphology 1 | 24
abnormal lens morphology 1 | 73
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
decreased body weight 1 | 174
decreased circulating amylase ... 1 | 24
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to t... 1 | 187
hydrops fetalis 1 | 22
increased CD4-positive, alpha ... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
tremors 1 | 34

Disease

osteosarcoma 27 | 7,933
ovarian cancer 27 | 8,484
Cancer 24 | 2,346
lung cancer 22 | 4,466
psoriasis 22 | 6,685
medulloblastoma, large-cell 19 | 6,234
glioblastoma 18 | 5,572
tuberculosis 16 | 1,557
lung carcinoma 15 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
interstitial cystitis 12 | 2,299
ulcerative colitis 12 | 2,087
atypical teratoid / rhabdoid tumor 9 | 4,369
group 4 medulloblastoma 9 | 1,875
juvenile dermatomyositis 9 | 1,189
malignant mesothelioma 9 | 3,162
non-small cell lung cancer 9 | 2,798
pilocytic astrocytoma 9 | 3,086
Rheumatoid Arthritis 8 | 1,160
acute myeloid leukemia 8 | 780
dermatomyositis 8 | 933
pancreatic cancer 8 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
subependymal giant cell astrocytoma 8 | 2,287
Carcinoma 7 | 2,147
IGA Glomerulonephritis 7 | 454
astrocytic glioma 7 | 2,241
cystic fibrosis 7 | 1,665
diabetes mellitus 7 | 1,663
ependymoma 7 | 2,514
oligodendroglioma 7 | 2,849
pediatric high grade glioma 7 | 2,712
posterior fossa group A ependymoma 7 | 1,511
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
Arthritis 5 | 248
Atopic dermatitis 5 | 944
Heat Stroke 5 | 12
Inflammatory bowel disease 5 | 142
Multiple myeloma 5 | 1,327
aldosterone-producing adenoma 5 | 664
astrocytoma 5 | 1,493
cutaneous lupus erythematosus 5 | 1,056
invasive ductal carcinoma 5 | 2,950
primitive neuroectodermal tumor 5 | 3,031
Alzheimer's disease 4 | 644
Asthma 4 | 349
Crohn's disease 4 | 304
Dermatitis 4 | 107
Glaucoma 4 | 134
Hypersensitivity reaction type II disease 4 | 235
Hypertension 4 | 287
Hypohidrotic ectodermal dysplasia 4 | 13
Influenza 4 | 142
Kidney disease 4 | 396
Liver disease 4 | 219
Lung disease 4 | 132
adult high grade glioma 4 | 2,148
group 3 medulloblastoma 4 | 2,254
hepatocellular carcinoma 4 | 532
lung adenocarcinoma 4 | 2,713
mucosa-associated lymphoid tissue lymphoma 4 | 480
non primary Sjogren syndrome sicca 4 | 840
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 789
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
Age related macular degeneration 3 | 84
Brain Ischemia 3 | 87
Breast cancer 3 | 3,094
Cleft palate 3 | 125
Colorectal Neoplasms 3 | 217
Coronary artery disease 3 | 240
Crohn Disease 3 | 97
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Fatty Liver 3 | 48
Heart disease 3 | 279
Heart failure 3 | 80
Histoplasmosis 3 | 22
Lung Injury 3 | 20
Lung Neoplasms 3 | 171
Mantle cell lymphoma 3 | 18
Multiple Sclerosis 3 | 498
Neoplasm Metastasis 3 | 138
Obesity 3 | 616
Perinatal necrotizing enterocolitis 3 | 18
Pneumonia 3 | 133
Reperfusion Injury 3 | 84
Spinal cord disease 3 | 22
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
atypical teratoid/rhabdoid tumor 3 | 1,095
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 430
medulloblastoma 3 | 1,524
pancreatic carcinoma 3 | 567
periodontitis 3 | 269
Cerebrovascular disease 2 | 231
Vasculitis 2 | 64

Tissue

Blood and immune system 59 | 17,995
Digestive Tract 59 | 18,473
Endocrine System 59 | 18,512
Female tissues 59 | 18,647
Liver and Pancreas 59 | 18,136
Nervous System 59 | 18,561
Respiratory system 59 | 17,484
Cardiovascular System 58 | 17,958
Skin and soft tissues 58 | 18,115
Urinary Tract 58 | 18,444
Male tissues 57 | 17,969

Target Family

Non-IDG 31 | 11,971
Kinase 14 | 634
Enzyme 8 | 4,146
Transcription Factor 5 | 1,400
GPCR 1 | 406

GO Process

I-kappaB kinase/NF-kappaB sign... 59 | 59
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.83055 69.0 145
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
TNFAIP3-interacting protein 2 TNIP2 Tbio Non-IDG -1.26538 19.5 139
Protein NLRC3 NLRC3 Tbio Non-IDG 0.00000 24
Toll-like receptor 3 TLR3 Tchem Non-IDG -3.00214 1147.2 751
Rho-associated protein kinase 2 ROCK2 Tclin Kinase -2.39656 248.3 472
Sharpin SHARPIN Tbio Non-IDG -1.20569 20.0 110
Tyrosine-protein kinase BTK BTK Tclin Kinase -2.98909 1061.8 721