Development Level

Tclin 2 | 613
Tbio 1 | 11,445

IMPC Phenotype

abnormal heart morphology 2 | 162
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal whole-body plethysmog... 1 | 4
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased cellular hemoglobin ... 1 | 1
increased circulating potassiu... 1 | 29
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
macrophthalmia 1 | 2
prolonged PR interval 1 | 15

Disease

Abnormality of retinal pigmentation 2 | 111
Abnormality of the retinal vasculature 2 | 59
Anteverted nostril 2 | 191
Atrial Fibrillation 2 | 124
Atypical scarring of skin 2 | 62
Autosomal recessive predisposition 2 | 1,442
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Broad flat nasal bridge 2 | 236
Carcinoma 2 | 11,493
Cataract 2 | 297
Chronic heart failure 2 | 46
Conductive hearing loss 2 | 123
Congenital anomaly of testis 2 | 52
Congenital hypoplasia of penis 2 | 176
Difficulties with night vision 2 | 87
Dull intelligence 2 | 645
Electroretinogram abnormal 2 | 95
Glaucoma 2 | 239
Hyperinsulinism 2 | 133
Hypogonadism 2 | 173
Intellectual disability 2 | 1,016
Keratoconus 2 | 113
Lens Opacities 2 | 231
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Myocardial Perfusion Imaging Adjunct 2 | 25
Nasal bridge wide 2 | 236
Night Blindness 2 | 101
Night blindness, progressive 2 | 51
Nystagmus 2 | 317
Obesity 2 | 678
Ophthalmoplegia 2 | 106
Optic Atrophy 2 | 242
Photodysphoria 2 | 121
Photophobia 2 | 121
Platelet Aggregation Inhibition 2 | 22
Poor school performance 2 | 645
Prevention of Cerebral Thrombosis 2 | 29
Retinal pigment epithelial abnormality 2 | 111
Retinitis Pigmentosa 2 | 226
Sensorineural Hearing Loss (disorder) 2 | 284
Abnormal rod and cone electroretinograms 1 | 2
Abnormality of macular pigmentation 1 | 16
Adenocarcinoma 1 | 122
Attenuation of retinal blood vessels 1 | 16
Blindness 1 | 88
Congenital stationary night blindness 1 | 29
Congenital stationary night blindness, autosomal dominant 2 1 | 1
Disease Models, Animal 1 | 155
Fundus dystrophy 1 | 83
Gastric adenocarcinoma 1 | 3
Hypoplasia of optic disc 1 | 12
Loss of peripheral vision 1 | 5
Low Vision 1 | 174
Macular pigmentary changes 1 | 16
Macular retinal edema 1 | 13
Multiple myeloma 1 | 1,332
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 1 | 1
Night blindness, congenital stationary 1 | 16
Night blindness, congenital stationary, complete 1 | 10
Night blindness, stationary 1 | 10
Oguchi disease 1 | 10
Pallor of optic disc 1 | 39
RETINITIS PIGMENTOSA 40 (disorder) 1 | 1
RETINITIS PIGMENTOSA 43 1 | 4
Reduced visual acuity 1 | 63
Retinal Degeneration 1 | 106
Retinitis pigmentosa 40 1 | 2
Severe myopia 1 | 22
Stomach Neoplasms 1 | 300
Tularemia 1 | 23
Tunnel visual field constriction 1 | 5
Visual Impairment 1 | 174
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
fibroadenoma 1 | 559
inflammatory breast cancer 1 | 286
lung adenocarcinoma 1 | 2,716
ovarian cancer 1 | 8,520
posterior fossa group B ependymoma 1 | 416
psoriasis 1 | 6,694
tuberculosis 1 | 2,010

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

GO Process

GMP metabolic process 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta PDE6B Tclin Enzyme -2.70127 507.4 69
GMP reductase 2 GMPR2 Tbio Enzyme -0.30103 1.94 84