Development Level

Tbio 67 | 11,445
Tchem 24 | 1,598
Tclin 6 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 9 | 278
abnormal embryo size 6 | 220
increased mean corpuscular vol... 3 | 92
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
decreased blood urea nitrogen ... 2 | 51
decreased circulating magnesiu... 2 | 13
decreased mean corpuscular hem... 2 | 31
edema 2 | 59
enlarged heart 2 | 210
female infertility 2 | 60
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
small testis 2 | 58
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal midbrain morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
brachydactyly 1 | 19
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
syndactyly 1 | 23
thrombocytopenia 1 | 56

Disease

Carcinoma 66 | 11,493
ovarian cancer 65 | 8,520
osteosarcoma 53 | 7,950
psoriasis 52 | 6,694
Cancer 51 | 2,499
medulloblastoma, large-cell 51 | 6,241
glioblastoma 50 | 5,792
lung cancer 49 | 4,740
group 3 medulloblastoma 48 | 4,104
atypical teratoid / rhabdoid tumor 46 | 5,112
malignant mesothelioma 41 | 3,232
Breast cancer 39 | 3,578
non-small cell lung cancer 39 | 2,890
primitive neuroectodermal tumor 39 | 3,035
adrenocortical carcinoma 31 | 1,428
adult high grade glioma 31 | 3,801
ependymoma 31 | 4,679
lung adenocarcinoma 29 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
invasive ductal carcinoma 25 | 2,951
oligodendroglioma 24 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
Astrocytoma, Pilocytic 22 | 3,081
ductal carcinoma in situ 21 | 1,745
nasopharyngeal carcinoma 19 | 1,058
colon cancer 18 | 1,478
tuberculosis 17 | 2,010
astrocytic glioma 15 | 2,597
Multiple myeloma 14 | 1,332
astrocytoma 14 | 1,146
pancreatic cancer 14 | 2,398
pediatric high grade glioma 14 | 1,064
breast carcinoma 13 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Kidney cancer 12 | 2,613
lung carcinoma 12 | 2,843
pituitary cancer 12 | 1,972
subependymal giant cell astrocytoma 12 | 2,287
Atopic dermatitis 11 | 952
Endometriosis 11 | 540
ulcerative colitis 11 | 1,819
Waldenstrons macroglobulinemia 10 | 765
acute quadriplegic myopathy 10 | 1,158
Autosomal recessive predisposition 9 | 1,442
Liver carcinoma 9 | 240
group 4 medulloblastoma 9 | 1,855
Carcinoma, Hepatocellular 8 | 228
Pick disease 8 | 1,894
Small head 8 | 374
Stomach Neoplasms 8 | 300
cystic fibrosis 8 | 1,696
dermatomyositis 8 | 966
interstitial cystitis 8 | 2,312
primary pancreatic ductal adenocarcinoma 8 | 1,109
Breast Neoplasms 7 | 445
Fetal Growth Retardation 7 | 189
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Mammary Neoplasms 7 | 425
Mammary Neoplasms, Experimental 7 | 154
Meier-Gorlin syndrome 7 | 10
Rheumatoid arthritis 7 | 1,191
Seckel syndrome 7 | 34
acute myeloid leukemia 7 | 783
diabetes mellitus 7 | 1,728
primary Sjogren syndrome 7 | 735
Animal Mammary Neoplasms 6 | 136
Dull intelligence 6 | 645
EAR, PATELLA, SHORT STATURE SYNDROME 6 | 7
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mammary Neoplasms, Animal 6 | 136
Melanoma 6 | 711
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
medulloblastoma 6 | 720
non primary Sjogren syndrome sicca 6 | 891
Adenoma 5 | 167
Cryptorchidism 5 | 296
Delayed bone age 5 | 136
Hypoplastic mandible condyle 5 | 275
Isolated growth hormone deficiency 5 | 30
Liver Cirrhosis, Experimental 5 | 769
Lung Neoplasms 5 | 232
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Prostatic Neoplasms 5 | 495
Vascular disease 5 | 319
juvenile dermatomyositis 5 | 1,187
tuberculosis and treatment for 6 months 5 | 409
Failure to gain weight 4 | 365
Schizophrenia 4 | 1,160
gastric cancer 4 | 459
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074

Tissue

Endocrine System 99 | 18,159
Blood and immune system 97 | 16,909
Female tissues 97 | 17,400
Nervous System 97 | 16,725
Respiratory system 97 | 16,393
Urinary Tract 97 | 16,678
Digestive Tract 96 | 17,369
Liver and Pancreas 96 | 16,750
Male tissues 96 | 17,142
Skin and soft tissues 96 | 17,230
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 45 | 12,091
Enzyme 30 | 4,145
Kinase 17 | 634
Transcription Factor 6 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

G1-S transition of mitotic cel... 100 | 100
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CDK2-associated and cullin domain-containing protein 1 CACUL1 Tbio Non-IDG -0.58734 5.65 98
Speedy protein A SPDYA Tbio Non-IDG -1.58097 42.8 145
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Origin recognition complex subunit 1 ORC1 Tbio Non-IDG -1.42573 28.0 148
Origin recognition complex subunit 2 ORC2 Tbio Non-IDG -0.68275 4.92 168
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A GSPT1 Tbio Enzyme -1.35573 22.8 99
Origin recognition complex subunit 5 ORC5 Tbio Non-IDG -1.50983 31.3 71
Probable G-protein coupled receptor 132 GPR132 Tchem GPCR -2.72228 494.8 185
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620