Development Level

Tdark 442 | 6,593
Tbio 354 | 11,651
Tchem 135 | 1,388
Tclin 122 | 612

Collection

GPCR: IDG Consortium (Targets) 89 | 126
RFA-RM-18-021 63 | 328
GPCR: IDG Consortium (Complete... 20 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased vertical activity 20 | 208
preweaning lethality, incomple... 20 | 499
preweaning lethality, complete... 19 | 979
abnormal behavior 14 | 298
enlarged heart 12 | 210
increased total body fat amoun... 12 | 134
decreased total body fat amoun... 11 | 207
abnormal heart morphology 10 | 162
decreased bone mineral content 10 | 151
hyperactivity 10 | 148
decreased lean body mass 8 | 135
prolonged QT interval 8 | 38
prolonged ST segment 8 | 36
decreased prepulse inhibition 7 | 82
hypoactivity 7 | 132
increased lean body mass 7 | 172
abnormal bone structure 6 | 187
abnormal kidney morphology 6 | 65
decreased grip strength 6 | 116
improved glucose tolerance 6 | 79
abnormal seminal vesicle morph... 5 | 114
decreased body weight 5 | 161
decreased bone mineral density 5 | 126
decreased circulating insulin ... 5 | 76
decreased fasted circulating g... 5 | 65
increased bone mineral content 5 | 108
increased circulating sodium l... 5 | 71
increased startle reflex 5 | 112
abnormal behavioral response t... 4 | 66
decreased circulating alanine ... 4 | 47
decreased hematocrit 4 | 46
decreased hemoglobin content 4 | 68
impaired glucose tolerance 4 | 75
increased circulating alkaline... 4 | 122
increased circulating calcium ... 4 | 34
increased circulating choleste... 4 | 66
increased fasted circulating g... 4 | 76
increased hemoglobin content 4 | 45
small superior vagus ganglion 4 | 74
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
decreased neutrophil cell numb... 3 | 42
decreased startle reflex 3 | 75
decreased threshold for audito... 3 | 26
female infertility 3 | 60
impaired pupillary reflex 3 | 26
increased circulating HDL chol... 3 | 80
increased circulating chloride... 3 | 41
increased circulating total pr... 3 | 28
increased circulating triglyce... 3 | 42
increased heart weight 3 | 62
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
male infertility 3 | 123
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal coat-hair pigmentatio... 2 | 64
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal skin coloration 2 | 25
abnormal skin morphology 2 | 50
abnormal testis morphology 2 | 43
abnormal vibrissa morphology 2 | 25
absent startle reflex 2 | 24
absent testes 2 | 6
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased IgE level 2 | 6
decreased T cell number 2 | 15
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating amylase ... 2 | 28
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
edema 2 | 59
embryonic lethality prior to t... 2 | 278
enlarged uterus 2 | 11
hydrometra 2 | 53
increased bone mineral density 2 | 72
increased circulating bilirubi... 2 | 16
increased circulating creatini... 2 | 38
increased circulating free fat... 2 | 20
increased circulating phosphat... 2 | 26
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
polycystic kidney 2 | 15
prolonged RR interval 2 | 8
small testis 2 | 58
tremors 2 | 39

Disease

Carcinoma 712 | 11,493
psoriasis 285 | 6,694
osteosarcoma 249 | 7,950
ovarian cancer 245 | 8,520
medulloblastoma, large-cell 237 | 6,241
glioblastoma 207 | 5,792
atypical teratoid / rhabdoid tumor 187 | 5,112
lung cancer 185 | 4,740
ependymoma 184 | 4,679
adult high grade glioma 170 | 3,801
diabetes mellitus 167 | 1,728
Cancer 152 | 2,499
lung carcinoma 148 | 2,843
Astrocytoma, Pilocytic 143 | 3,081
interstitial cystitis 132 | 2,312
group 3 medulloblastoma 127 | 4,104
Breast cancer 122 | 3,578
malignant mesothelioma 121 | 3,232
invasive ductal carcinoma 120 | 2,951
non-small cell lung cancer 120 | 2,890
Schizophrenia 119 | 1,160
lung adenocarcinoma 119 | 2,716
Kidney cancer 115 | 2,613
primitive neuroectodermal tumor 114 | 3,035
oligodendroglioma 113 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 108 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 107 | 2,989
astrocytic glioma 106 | 2,597
ulcerative colitis 105 | 1,819
tuberculosis 100 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 99 | 3,291
Obesity 93 | 678
Depressive disorder 88 | 409
Bipolar Disorder 87 | 666
pancreatic cancer 87 | 2,398
pituitary cancer 85 | 1,972
ductal carcinoma in situ 77 | 1,745
breast carcinoma 76 | 1,638
subependymal giant cell astrocytoma 76 | 2,287
cystic fibrosis 75 | 1,696
colon cancer 74 | 1,478
Asthma 73 | 385
Hypertension 71 | 396
Mental Depression 68 | 333
group 4 medulloblastoma 67 | 1,855
Alcoholic Intoxication, Chronic 66 | 289
Pick disease 62 | 1,894
cutaneous lupus erythematosus 62 | 1,057
Major Depressive Disorder 57 | 301
Rheumatoid arthritis 55 | 1,191
Mood Disorders 53 | 184
adrenocortical carcinoma 53 | 1,428
Multiple Sclerosis 49 | 540
Autosomal recessive predisposition 47 | 1,442
Epilepsy 44 | 792
Hypertensive disease 44 | 292
Parkinson's disease 44 | 392
Unipolar Depression 44 | 250
primary Sjogren syndrome 44 | 735
astrocytoma 42 | 1,146
Atopic dermatitis 41 | 952
Liver Cirrhosis, Experimental 41 | 769
Kidney disease 40 | 430
Atherosclerosis 39 | 291
Melanoma 39 | 711
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,962
Alzheimer's disease 37 | 658
juvenile dermatomyositis 37 | 1,187
Pain 36 | 103
Seizures 36 | 596
Migraine 35 | 83
mucosa-associated lymphoid tissue lymphoma 35 | 484
Coronary artery disease 34 | 268
Pain agnosia 34 | 104
Arthritis 33 | 290
Cerebrovascular disease 33 | 238
Vascular disease 33 | 319
pediatric high grade glioma 33 | 1,064
Autistic Disorder 32 | 364
Liver cancer 32 | 604
active Crohn's disease 32 | 922
esophageal adenocarcinoma 32 | 737
Allergic rhinitis 31 | 95
Skin cancer 31 | 469
fibroadenoma 31 | 559
gastric carcinoma 31 | 807
hepatocellular carcinoma 31 | 547
non primary Sjogren syndrome sicca 31 | 891
Endometriosis 30 | 540
Heart disease 30 | 306
Hyperalgesia 30 | 83
Hypotension 30 | 82
active ulcerative colitis 30 | 764
medulloblastoma 30 | 720
primary pancreatic ductal adenocarcinoma 30 | 1,109
Adenoma 29 | 167
Alcohol dependence 29 | 107
Down syndrome 29 | 499
Intellectual disability 29 | 1,016
spina bifida 28 | 1,074

Tissue

Endocrine System 712 | 18,159
Female tissues 618 | 17,400
Digestive Tract 598 | 17,369
Skin and soft tissues 583 | 17,230
Blood and immune system 581 | 16,909
Male tissues 581 | 17,142
Nervous System 577 | 16,725
Liver and Pancreas 548 | 16,750
Urinary Tract 547 | 16,678
Respiratory system 534 | 16,393
Cardiovascular System 450 | 15,192

Target Family

oGPCR 409 | 421
GPCR 334 | 408
Non-IDG 241 | 12,091
Enzyme 47 | 4,145
Kinase 17 | 634
Ion Channel 2 | 344
Transcription Factor 2 | 1,400
Transporter 1 | 473

GO Process

G-protein coupled receptor sig... 1,053 | 1,053
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
Olfactory receptor 7D2 OR7D2 Tdark oGPCR 0.00000 2
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Olfactory receptor 5B21 OR5B21 Tdark oGPCR 0.00000 4