Development Level

Tbio 7 | 11,445
Tclin 5 | 613
Tchem 3 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal behavior 2 | 298
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased startle reflex 1 | 112
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

psoriasis 11 | 6,694
Carcinoma 9 | 11,493
glioblastoma 9 | 5,792
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
Schizophrenia 7 | 1,160
atypical teratoid / rhabdoid tumor 7 | 5,112
adult high grade glioma 6 | 3,801
colon cancer 6 | 1,478
ependymoma 6 | 4,679
group 4 medulloblastoma 6 | 1,855
Astrocytoma, Pilocytic 5 | 3,081
Biliary dyskinesia 5 | 7
Chronic gastritis 5 | 5
Chronic obstructive lung disease 5 | 6
Epilepsy 5 | 792
Excessive salivation 5 | 5
Gastric ulcer 5 | 33
General anesthesia 5 | 53
Peptic Ulcer 5 | 27
Urinary Incontinence 5 | 50
Vagal Reflex Bradycardia 5 | 5
ulcerative colitis 5 | 1,819
Breast cancer 4 | 3,578
Depressive disorder 4 | 409
Melanoma 4 | 711
Rheumatoid arthritis 4 | 1,191
Skin cancer 4 | 469
astrocytic glioma 4 | 2,597
diabetes mellitus 4 | 1,728
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Bipolar Disorder 3 | 666
Bladder muscle dysfunction - overactive 3 | 4
Cholinesterase Inhibitors Toxicity 3 | 4
Congenital Heart Defects 3 | 58
Dysuria 3 | 26
Gastrointestinal Radiography Adjunct 3 | 11
Increased Urinary Frequency 3 | 11
Major Depressive Disorder 3 | 301
Muscarine Toxicity 3 | 3
Perioperative Mydriasis 3 | 3
Pick disease 3 | 1,894
Sinus bradycardia 3 | 7
Urge incontinence of urine 3 | 3
Urgent desire to urinate 3 | 11
Urinary Tract Irritation 3 | 24
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Abnormal vision 2 | 52
Acute cystitis 2 | 35
Allergic rhinitis 2 | 94
Autosomal recessive predisposition 2 | 1,442
Bradycardia 2 | 36
Cancer 2 | 2,499
Cycloplegia 2 | 12
DOID:2415 2 | 5
Dilated pupil 2 | 6
Enterocolitis 2 | 8
Heart Defects, Congenital 2 | 37
Hyperreflexia 2 | 209
Intellectual disability 2 | 1,016
Irritable bowel syndrome 2 | 60
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
MYELODYSPLASTIC SYNDROME 2 | 53
Malignant melanoma of choroid 2 | 3
Malignant melanoma of ciliary body 2 | 3
Malignant melanoma of iris 2 | 4
Mental Depression 2 | 333
Mood Disorders 2 | 184
Nasal discharge 2 | 24
Neurogenic bladder 2 | 16
Ocular cancer 2 | 7
Parkinson's disease 2 | 392
Phakomatosis cesioflammea 2 | 2
Retention of urine 2 | 3
Retinal Detachment 2 | 51
Seizures 2 | 596
Unipolar Depression 2 | 250
Uveal melanoma 2 | 20
Xerostomia Secondary to Sjogren's Syndrome 2 | 2
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
group 3 medulloblastoma 2 | 4,104
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
Extrapyramidal disease 1 | 8
Hypocalciuric hypercalcemia, familial, type II 1 | 1
Marijuana Abuse 1 | 31
Pain 1 | 103

Tissue

Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Nervous System 15 | 16,725
Skin and soft tissues 15 | 17,230
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Male tissues 14 | 17,142
Respiratory system 14 | 16,393
Urinary Tract 13 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 7 | 12,091
GPCR 5 | 408
Enzyme 2 | 4,145
Kinase 1 | 634

GO Process

G-protein coupled acetylcholin... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Agrin AGRN Tbio Non-IDG -2.73844 569.8 122
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Muscarinic acetylcholine receptor M2 CHRM2 Tclin GPCR -2.70017 498.2 391
Muscarinic acetylcholine receptor M3 CHRM3 Tclin GPCR -2.65353 447.9 234
Beta-adrenergic receptor kinase 1 GRK2 Tchem Kinase -2.61043 428.8 455
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Muscarinic acetylcholine receptor M1 CHRM1 Tclin GPCR -2.16159 140.8 222
Muscarinic acetylcholine receptor M4 CHRM4 Tclin GPCR -1.90995 79.8 130
Cyclin-dependent kinase 5 activator 1 CDK5R1 Tchem Enzyme -1.77914 52.4 217